Search Results - "Burger, Koert N.J"
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TIP47 functions in the biogenesis of lipid droplets
Published in The Journal of cell biology (18-05-2009)“…TIP47 (tail-interacting protein of 47 kD) was characterized as a cargo selection device for mannose 6-phosphate receptors (MPRs), directing their transport…”
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ER-to-Golgi Carriers Arise through Direct En Bloc Protrusion and Multistage Maturation of Specialized ER Exit Domains
Published in Developmental cell (01-10-2003)“…Protein transport between the ER and the Golgi in mammalian cells occurs via large pleiomorphic carriers, and most current models suggest that these are formed…”
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Nanocapsules: lipid-coated aggregates of cisplatin with high cytotoxicity
Published in Nature medicine (01-01-2002)“…Cisplatin is one of the most widely used agents in the treatment of solid tumors, but its clinical utility is limited by toxicity. The development of less…”
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Biophysics and function of phosphatidic acid: A molecular perspective
Published in Biochimica et biophysica acta (01-09-2009)“…Phosphatidic acid is the simplest (diacyl)glycerophospholipid present in cells and is now a well established second messenger with direct biological functions…”
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Quantitative Label-Free Imaging of Lipid Composition and Packing of Individual Cellular Lipid Droplets Using Multiplex CARS Microscopy
Published in Biophysical journal (15-11-2008)“…Lipid droplets (LDs) are highly dynamic organelles that perform multiple functions, including the regulated storage and release of cholesterol and fatty acids…”
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The effect of immediate breast reconstruction on the timing of adjuvant chemotherapy: a systematic review
Published in Breast cancer research and treatment (01-09-2015)“…Adjuvant chemotherapy is often needed to achieve adequate breast cancer control. The increasing popularity of immediate breast reconstruction (IBR) raises…”
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An Electrostatic/Hydrogen Bond Switch as the Basis for the Specific Interaction of Phosphatidic Acid with Proteins
Published in The Journal of biological chemistry (13-04-2007)“…Phosphatidic acid (PA) is a minor but important phospholipid that, through specific interactions with proteins, plays a central role in several key cellular…”
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Diacylglycerol is required for the formation of COPI vesicles in the Golgi-to-ER transport pathway
Published in Molecular biology of the cell (01-09-2007)“…Diacylglycerol is necessary for trans-Golgi network (TGN) to cell surface transport, but its functional relevance in the early secretory pathway is unclear…”
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Imaging of chemical and physical state of individual cellular lipid droplets using multiplex CARS microscopy
Published in Journal of Raman spectroscopy (01-07-2009)“…Cellular lipid droplets are organelles that carry out important functions such as the regulated storage and release of cholesterol and fatty acids (FAs). Lipid…”
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Small Cargo Proteins and Large Aggregates Can Traverse the Golgi by a Common Mechanism without Leaving the Lumen of Cisternae
Published in The Journal of cell biology (24-12-2001)“…Procollagen (PC)-I aggregates transit through the Golgi complex without leaving the lumen of Golgi cisternae. Based on this evidence, we have proposed that…”
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Sensing Membrane Curvature
Published in Developmental Cell (01-12-2003)“…Transport vesicle formation and fusion are highly regulated processes that require the sequential assembly and disassembly of proteinacious membrane coats…”
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Book Review Journal Article -
12
Dietary fiber, carbohydrate quality and quantity, and mortality risk of individuals with diabetes mellitus
Published in PloS one (23-08-2012)“…Dietary fiber, carbohydrate quality and quantity are associated with mortality risk in the general population. Whether this is also the case among diabetes…”
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13
Guideline on the diagnosis and treatment of primary idiopathic clubfoot
Published in Acta orthopaedica (04-05-2017)“…Abstract - A delegation of 6 pediatric orthopedic surgeons from the Dutch Orthopedic Association (NOV) and 2 members of the board of the Dutch Parents'…”
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Dietary glycemic load and glycemic index and risk of coronary heart disease and stroke in Dutch men and women: the EPIC-MORGEN study
Published in PloS one (05-10-2011)“…The associations of glycemic load (GL) and glycemic index (GI) with the risk of cardiovascular diseases (CVD) are not well-established, particularly in men,…”
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15
Spontaneous Curvature of Phosphatidic Acid and Lysophosphatidic Acid
Published in Biochemistry (Easton) (15-02-2005)“…The formation of phosphatidic acid (PA) from lysophosphatidic acid (LPA), diacylglycerol, or phosphatidylcholine plays a key role in the regulation of…”
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Modulation of Membrane Curvature by Phosphatidic Acid and Lysophosphatidic Acid
Published in Traffic (Copenhagen, Denmark) (01-03-2003)“…The local generation of phosphatidic acid plays a key role in the regulation of intracellular membrane transport through mechanisms which are largely unknown…”
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What Makes the Bioactive Lipids Phosphatidic Acid and Lysophosphatidic Acid So Special?
Published in Biochemistry (Easton) (27-12-2005)“…Phosphatidic acid and lysophosphatidic acid are minor but important anionic bioactive lipids involved in a number of key cellular processes, yet these…”
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Greasing Membrane Fusion and Fission Machineries
Published in Traffic (Copenhagen, Denmark) (01-08-2000)“…Biological membrane fusion is a local‐point event, extremely fast, and under strict control. Proteins are responsible for the mutual recognition of the fusion…”
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Secretory traffic triggers the formation of tubular continuities across Golgi sub-compartments
Published in Nature cell biology (01-11-2004)“…The organization of secretory traffic remains unclear, mainly because of the complex structure and dynamics of the secretory pathway. We have thus studied a…”
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Insertion of apoLp-III into a lipid monolayer is more favorable for saturated, more ordered, acyl-chains
Published in Biochimica et biophysica acta (01-01-2014)“…Neutral lipid transport in mammals is complicated involving many types of apolipoprotein. The exchangeable apolipoproteins mediate the transfer of hydrophobic…”
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