Search Results - "Burek, C L"

Antibodies to selected minor target antigens in patients with anti-neutrophil cytoplasmic antibodies (ANCA) by Talor, M.V, Stone, J.H, Stebbing, J, Barin, J, Rose, N.R, Burek, C.L

“…In patients with anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis, indirect immunofluorescence (IF) distinguishes between cytoplasmic…”
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Mercury exposure, malaria, and serum antinuclear/antinucleolar antibodies in Amazon populations in Brazil: a cross-sectional study by Silva, Ines A, Nyland, Jennifer F, Gorman, Andrew, Perisse, Andre, Ventura, Ana Maria, Santos, Elizabeth C O, Souza, Jose M de, Burek, C L, Rose, Noel R, Silbergeld, Ellen K

“…Mercury is an immunotoxic metal that induces autoimmune disease in rodents. Highly susceptible mouse strains such as SJL/N, A.SW, B10.S (H-2s) develop multiple…”
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Iodination of human thyroglobulin (Tg) alters its immunoreactivity. I. Iodination alters multiple epitopes of human Tg by SABOORI, A. M, ROSE, N. R, BRESLER, H. S, VLADUT-TALOR, M, BUREK, C. L

“…Human Tg, the site of synthesis of thyroid hormones, thyroxine (T4) and triiodothyronine (T3), is one of the major autoantigens in autoimmune thyroiditis. The…”
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Heterogeneity of the thyroglobulin epitopes associated with circulating thyroid hormone autoantibodies in Hashimoto's thyroiditis and non-autoimmune thyroid diseases by BENVENGA, S, BUREK, C. L, TALOR, M, ROSE, N. R, TRIMARCHI, F

“…We previously implicated TG leakage from fine-needle aspiration biopsy (FNAB) as responsible for circulating thyroid hormone autoantibodies (THAb). However,…”
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Iodination of murine thyroglobulin enhances autoimmune reactivity in the NOD.H2h4 mouse by Barin, J. G., Talor, M. V., Sharma, R. B., Rose, N. R., Burek, C. L.

“…Summary Autoimmune thyroiditis in humans has been linked to excess iodine intake. A causative relationship between dietary iodine and thyroiditis has been…”
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Heritability analysis of IgG4 antibodies in autoimmune thyroid disease by Outschoorn, I. M., Talor, M. V., Burek, C. L., Hoffman, W. H., Rose, N. R.

“…Abstract A study of IgG4 autoantibody levels in juvenile thyroid disease patients showed evidence of heritability using the ROMP screening method. These levels…”
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Iodination of human thyroglobulin (Tg) alters its immunoreactivity. II. Fine specificity of a monoclonal antibody that recognizes iodinated Tg by SABOORI, A. M, ROSE, N. R, BUREK, C. L

“…In a previous investigation, we found that murine MoAb 42C3, raised against human Tg, recognized Tg differently depending upon its level of iodination of Tg. A…”
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IgG subclass distribution of thyroglobulin antibodies in patients with thyroid disease by CATUREGLI, P., KUPPERS, R. C., MARIOTTI, S., BUREK, C. LVNNE, PINCHERA, A., LADENSON, P. W., ROSE, N. R.

“…SUMMARY The IgG subclass distribution of thyroglobulin antibodies (TgAb) has been studied in Hashimoto and Graves’ patients by several investigators with…”
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Evidence for genetic transmission of thyroid peroxidase autoantibody epitopic fingerprints by JAUME, J. C, JIN GUO, MCLACHLAN, S. M, PAULS, D. L, ZAKARIJA, M, MCKENZIE, J. M, EGELAND, J. A, BUREK, C. L, ROSE, N. R, HOFFMAN, W. H, RAPOPORT, B

“…Autoimmune thyroid disease is characterized by the tendency to cluster in families and by IgG class autoantibodies to antigens such as thyroid peroxidase…”
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Circulating heart-reactive antibodies in patients with myocarditis or cardiomyopathy by Neumann, David A., Lynne Burek, C., Baughman, Kenneth L., Rose, Noel R., Herskowitz, Ahvie

“…Heart-reactive antibodies are commonly observed in patients with myocarditis or cardiomyopathy. Such antibodies may be important in the pathogenesis of these…”
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Induction of major histocompatibility complex antigens within the myocardium of patients with active myocarditis: A nonhistologic marker of myocarditis by Herskowitz, Ahvie, Ahmed-ansari, Aftab, Neumann, David A., Beschorner, William E., Rose, Noel R., Soule, Lisa M., Lynne Burek, C., Sell, Kenneth W., Baughman, Kenneth L.

“…The histologic diagnosis of active myocarditis is frequently difficult to establish. A nonhistologic marker of immune activation would be clinically useful in…”
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Whole-blood proliferation assay for autoimmune thyroid disease: comparison to density-gradient separated-peripheral blood lymphocytes by Butscher, W G, Ladenson, P W, Burek, C L

“…Autoimmune thyroid diseases feature prominent cellular infiltration of the thyroid gland as well as autoantibody production to thyroid antigens. The most…”
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Iodine is Essential for Human T Cell Recognition of Human Thyroglobulin by Rasooly, Linda, Rose, Noel R., Saboori, Ali M., Ladenson, Paul W., Burek, C. Lynne

“…Here we describe for the first time that recognition by human T cells of human thyroglobulin depends upon its iodine content. We have examined the…”
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Thyroid peroxidase autoantibody epitopic ‘fingerprints’ in juvenile Hashimoto's thyroiditis: evidence for conservation over time and in families by JAUME, J. C., BUREK, C. L., HOFFMAN, W. H., ROSE, N. R., MCLACHLAN, S. M., RAPOPORT, B.

“…In Hashimoto's thyroiditis, the humoral component is manifest by autoantibodies to thyroid peroxidase (TPO). Epitopic ‘fingerprinting’ of polyclonal serum TPO…”
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Iodination of murine thyroglobulin enhances autoimmune reactivity in the NOD.H2 mouse by Barin, J G, Talor, M V, Sharma, R B, Rose, N R, Burek, C L

“…Autoimmune thyroiditis in humans has been linked to excess iodine intake. A causative relationship between dietary iodine and thyroiditis has been clearly…”
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The detection of antithyroglobulin activity in human serum monoclonal immunoglobulins (monoclonal gammopathies) by YATIV, N, BUSKILA, D, BLANK, M, BUREK, C. L, ROSE, N. R, SHOENFIELD, Y

“…The sera of 159 patients with monoclonal gammopathies were examined for the presence of anti-thyroglobulin (Tg) activity. An enzyme-linked immunosorbent assay…”
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Cyclosporine therapy suppresses ocular and lacrimal gland disease in MRL/Mp-lpr/lpr mice by Jabs, DA, Lee, B, Burek, CL, Saboori, AM, Prendergast, RA

“…MRL/Mp-lpr/lpr (MRL/lpr) mice spontaneously develop an autoimmune disease characterized by lymphoproliferation, vasculitis, glomerulonephritis, autoantibody…”
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Anti-CD4 monoclonal antibody therapy suppresses autoimmune disease in MRL/Mp-lpr/lpr mice by Jabs, D A, Burek, C L, Hu, Q, Kuppers, R C, Lee, B, Prendergast, R A

“…MRL/Mp-lpr/lpr (MRL/lpr) mice spontaneously develop systemic autoimmune disease, characterized by vasculitis, lymphadenopathy, glomerulonephritis, and…”
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Epitopes on thyroglobulin: a study of patients with thyroid disease by Caturegli, P, Mariotti, S, Kuppers, R C, Burek, C L, Pinchera, A, Rose, N R

“…Thyroglobulin antibodies (TgAbs) are typically found in autoimmune thyroid diseases and, more rarely, in nonautoimmune thyroid diseases and healthy subjects…”
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Linking iodine with autoimmune thyroiditis by Rose, N R, Rasooly, L, Saboori, A M, Burek, C L

“…A great deal of circumstantial evidence has linked iodine with the rising incidence of autoimmune thyroiditis in the United States. In our investigations, we…”
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