Search Results - "Burdack, Christoph"

Highly substituted indol-2-ones, quinoxalin-2-ones and benzodiazepin-2,5-diones via a new Ugi(4CR)-Pd assisted N-aryl amidation strategy by Kalinski, Cédric, Umkehrer, Michael, Ross, Günther, Kolb, Jürgen, Burdack, Christoph, Hiller, Wolfgang

“…A new strategy employing an Ugi four-component reaction and a palladium-assisted intramolecular N-aryl amidation reaction is reported. The straight forward…”
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A novel one-pot synthesis of highly diverse indole scaffolds by the Ugi/Heck reaction by Kalinski, Cédric, Umkehrer, Michael, Schmidt, Jürgen, Ross, Günther, Kolb, Jürgen, Burdack, Christoph, Hiller, Wolfgang, Hoffmann, Stephan D.

“…A novel one-pot two-step multi component reaction of acrylic aldehydes, bromoanilines, acids and isocyanides yielding polysubstituted indoles is described. The…”
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Tetramic acid derivatives via Ugi–Dieckmann-reaction by Spatz, Julia H., Welsch, Sebastian J., Duhaut, David-Emmanuel, Jäger, Nadine, Boursier, Thomas, Fredrich, Martin, Allmendinger, Lars, Ross, Günther, Kolb, Jürgen, Burdack, Christoph, Umkehrer, Michael

“…Tetramic acid derivatives constitute an important class of nitrogen containing heterocycles, and are key structural motifs in many natural products of…”
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Pd II/IV catalyzed oxidative cyclization of 1,6-enynes derived by Ugi-4-component reaction by Welsch, Sebastian J., Umkehrer, Michael, Ross, Günther, Kolb, Jürgen, Burdack, Christoph, Wessjohann, Ludger A.

“…A variety of 1,6-enynes were synthesized by an Ugi-reaction and further elaborated by a Pd II/IV catalyzed oxidative cyclization to produce N-substituted…”
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A new and versatile one-pot synthesis of indol-2-ones by a novel Ugi-four-component-Heck reaction by Umkehrer, Michael, Kalinski, Cédric, Kolb, Jürgen, Burdack, Christoph

“…A novel one-pot-synthesis of highly substituted indol-2-ones using a combination of Ugi and Heck reaction (U-4CR-Heck) is described. The synthesized…”
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Synthesis of substituted imidazolines by an Ugi/Staudinger/aza-Wittig sequence by Welsch, Sebastian J., Umkehrer, Michael, Kalinski, Cedric, Ross, Günther, Burdack, Christoph, Kolb, Jürgen, Wild, Martina, Ehrlich, Anja, Wessjohann, Ludger A.

“…[Display omitted] A series of 2-(acetamide-2-yl)-imidazolines (II) with 5 points of diversity were prepared by an Ugi-4CR–Staudinger–aza-Wittig-sequence…”
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On the industrial applications of MCRs: molecular diversity in drug discovery and generic drug synthesis by Kalinski, Cédric, Umkehrer, Michael, Weber, Lutz, Kolb, Jürgen, Burdack, Christoph, Ross, Günther

“…During the last decades, multicomponent chemistry has gained much attention in pharmaceutical research, especially in the context of lead finding and…”
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Palladium and copper catalyzed cyclizations of hydrazine derived Ugi products: facile synthesis of substituted indazolones and hydroxytriazafluorendiones by Welsch, Sebastian J., Kalinski, Cédric, Umkehrer, Michael, Ross, Günther, Kolb, Jürgen, Burdack, Christoph, Wessjohann, Ludger A.

“…Indazolones are medicinally relevant targets. Herein we disclose an improved synthesis to N′-(acetamido-2-yl)-substituted indazolones with four points of…”
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Pd super(II/IV catalyzed oxidative cyclization of 1,6-enynes derived by Ugi-4-component reaction) by Welsch, Sebastian J, Umkehrer, Michael, Ross, Guenther, Kolb, Juergen, Burdack, Christoph, Wessjohann, Ludger A

“…A variety of 1,6-enynes were synthesized by an Ugi-reaction and further elaborated by a Pd super(II/IV catalyzed oxidative cyclization to produce N-substituted…”
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PdII/IV catalyzed oxidative cyclization of 1,6-enynes derived by Ugi-4-component reaction by WELSCH, Sebastian J, UMKEHRER, Michael, ROSS, Günther, KOLB, Jürgen, BURDACK, Christoph, WESSJOHANN, Ludger A

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Expeditious synthesis of imidazo[1,2- c]pyrimidines via a [4+1]-cycloaddition by Umkehrer, Michael, Ross, Günther, Jäger, Nadine, Burdack, Christoph, Kolb, Jürgen, Hu, Hong, Alvim-Gaston, Maria, Hulme, Christopher

“…A new and versatile synthesis of imidazo[1,2- c]pyrimidines via a [4+1]-cycloaddition is described. The reported novel synthetic approach leads to…”
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Synthesis of tetrazolopiperazine building blocks by a novel multi-component reaction by Umkehrer, Michael, Kolb, Jürgen, Burdack, Christoph, Ross, Günther, Hiller, Wolfgang

“…[Display omitted] A novel Ugi-five-centre-four-component reaction (U-5C-4CR) of aldehydes, primary amines, trimethylsilylazide and 2-isocyanoethyltosylate…”
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Combinatorial synthesis of 4-oxo-4H-imidazo[1,5-a]quinoxalines and 4-oxo-4H-pyrazolo[1,5-a]quinoxalines by Spatz, Julia H., Umkehrer, Michael, Kalinski, Cédric, Ross, Günther, Burdack, Christoph, Kolb, Jürgen, Bach, Thorsten

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New cleavable isocyanides for the combinatorial synthesis of α-amino acid analogue tetrazoles by Mayer, Josef, Umkehrer, Michael, Kalinski, Cédric, Ross, Günther, Kolb, Jürgen, Burdack, Christoph, Hiller, Wolfgang

“…3-Substituted 3-isocyano propionates as new cleavable isocyanides in combinatorial tetrazole synthesis via Ugi-reaction are introduced. The obtained…”
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Combinatorial synthesis of 4-oxo-4 H-imidazo[1,5- a]quinoxalines and 4-oxo-4 H-pyrazolo[1,5- a]quinoxalines by Spatz, Julia H., Umkehrer, Michael, Kalinski, Cédric, Ross, Günther, Burdack, Christoph, Kolb, Jürgen, Bach, Thorsten

“…A combinatorial synthetic route yielding imidazo[1,5- a]quinoxalines and pyrazolo[1,5- a]quinoxalines is described. The use of 2-fluoroaniline and 1…”
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Diversity oriented synthesis of benzoxazoles and benzothiazoles by Spatz, Julia H., Bach, Thorsten, Umkehrer, Michael, Bardin, Julien, Ross, Günther, Burdack, Christoph, Kolb, Jürgen

“…A combinatorial synthetic route yielding benzoxazoles and benzothiazoles is described. The use of o-halophenylisocyanides in the Ugi reaction (U-4CR) followed…”
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