Search Results - "Burdach, Stefan Eg"
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A costimulatory chimeric antigen receptor targeting TROP2 enhances the cytotoxicity of NK cells expressing a T cell receptor reactive to human papillomavirus type 16 E7
Published in Cancer letters (10-07-2023)“…Immune cells modified to express a tumor-reactive T cell receptor (TCR) have shown limited efficacy as stand-alone therapy against solid tumors. Genital and…”
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Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles
Published in The Journal of clinical investigation (01-05-2024)“…Aberrant expression of the E26 transformation-specific (ETS) transcription factors characterizes numerous human malignancies. Many of these proteins, including…”
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Abstract B058: Clusterin overexpression in therapeutic T cell induces resistance to exhaustion
Published in Cancer research (Chicago, Ill.) (05-09-2024)“…Ewing Sarcoma (EwS) is characterized by an immunosuppressive tumor microenvironment (TME), which promotes T cell exhaustion, among other factors by chronic…”
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DNA Microarrays reveal relationship of ewing family tumors to both endothelial and fetal neural crest-derived cells and define novel targets
Published in Cancer research (Chicago, Ill.) (15-11-2004)“…Ewing family tumors (EFTs) are small round blue cell tumors that show features of neuroectodermal differentiation. However, the histogenetic origin of EFTs is…”
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