Search Results - "Burch, John B.E"
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Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart
Published in Developmental biology (15-06-2012)“…The importance of the epicardium for myocardial and valvuloseptal development has been well established; perturbation of epicardial development results in…”
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Differential Notch Signaling in the Epicardium Is Required for Cardiac Inflow Development and Coronary Vessel Morphogenesis
Published in Circulation research (01-04-2011)“…RATIONALE:The proepicardium is a transient structure comprising epicardial progenitor cells located at the posterior limit of the embryonic cardiac inflow. A…”
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Identification and characterization of a novel Schwann and outflow tract endocardial cushion lineage-restricted periostin enhancer
Published in Developmental biology (15-07-2007)“…Periostin is a fasciclin-containing adhesive glycoprotein that facilitates the migration and differentiation of cells that have undergone…”
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Chicken repeat 1 (CR1) elements, which define an ancient family of vertebrate non-LTR retrotransposons, contain two closely spaced open reading frames
Published in Gene (15-09-1997)“…Chicken repeat 1 (CR1) elements comprise a family of non-long terminal repeat (LTR) retrotransposons that have several noteworthy features. For example,…”
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Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor
Published in Circulation (New York, N.Y.) (27-11-2007)“…The atrioventricular (AV) node is essential for the sequential excitation and optimized contraction of the adult multichambered heart; however, relatively…”
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Alk3/Bmpr1a Receptor Is Required for Development of the Atrioventricular Canal Into Valves and Annulus Fibrosus
Published in Circulation research (05-08-2005)“…Endocardial cushions are precursors of mature atrioventricular (AV) valves. Their formation is induced by signaling molecules originating from the AV…”
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Architectural Plan for the Heart: Early Patterning and Delineation of the Chambers and the Nodes
Published in Trends in cardiovascular medicine (01-11-2004)“…During folding of the embryo, lateroanterior visceral mesoderm forms the embryonic tubular heart at the midline, just ventral to the foregut. In mice, this…”
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Epicardial Induction of Fetal Cardiomyocyte Proliferation via a Retinoic Acid-Inducible Trophic Factor
Published in Developmental biology (01-10-2002)“…Mouse embryos lacking the retinoic acid receptor RXRα properly undergo the early steps of heart development, but then fail to initiate a proliferative…”
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Apoptosis in the developing mouse heart
Published in Developmental dynamics (01-09-2006)“…Apoptosis occurs at high frequency in the myocardium of the developing avian cardiac outflow tract (OFT). Up‐ or down‐regulating apoptosis results in defects…”
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Regulation of GATA gene expression during vertebrate development
Published in Seminars in cell & developmental biology (01-02-2005)“…GATA factors regulate critical events in hematopoietic lineages (GATA-1/2/3), the heart and gut (GATA-4/5/6) and various other tissues. Transgenic approaches…”
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The sinus venosus progenitors separate and diversify from the first and second heart fields early in development
Published in Cardiovascular research (01-07-2010)“…Aims During development, the heart tube grows by differentiation of Isl1+/Nkx2-5+ progenitors to the arterial and venous pole and dorsal mesocardium. However,…”
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The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature
Published in Development (Cambridge) (01-12-2005)“…Most internal organs are situated in a coelomic cavity and are covered by a mesothelium. During heart development, epicardial cells (a mesothelium) move to and…”
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A role for bone morphogenetic proteins in the induction of cardiac myogenesis
Published in Genes & development (15-02-1997)“…Little is known about the molecular mechanisms that govern heart specification in vertebrates. Here we demonstrate that bone morphogenetic protein (BMP)…”
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Bone Marrow Cells Transdifferentiate to Cardiomyocytes When Introduced into the Embryonic Heart
Published in Stem cells (Dayton, Ohio) (01-05-2006)“…Since rates of cardiomyocyte generation in the embryo are much higher than within the adult, we explored whether the embryonic heart would serve as useful…”
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GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut
Published in The Journal of biological chemistry (16-09-1994)“…We describe experiments which show that: 1) two previously identified members of the GATA family of transcription factors (both of which were originally called…”
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Common role for each of the cGATA-4/5/6 genes in the regulation of cardiac morphogenesis
Published in Developmental genetics (1998)“…The GATA‐4/5/6 genes encode transcription factors implicated previously in the regulation of cardiac‐specific differentiation programs. However, recent…”
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Subfamilies of CR1 non-LTR retrotransposons have different 5′UTR sequences but are otherwise conserved
Published in Gene (07-03-2001)Get full text
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Modular Regulation of cGATA-5 Gene Expression in the Developing Heart and Gut
Published in Developmental biology (01-01-2000)“…The evolutionarily conserved GATA-5 transcription factor is an early and persistent marker of heart and gut development in diverse vertebrate species. To…”
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The Chicken GATA-6 Locus Contains Multiple Control Regions That Confer Distinct Patterns of Heart Region-specific Expression in Transgenic Mouse Embryos
Published in The Journal of biological chemistry (07-11-1997)“…The GATA-6 transcription factor is expressed in cardiogenic cells and during subsequent stages of heart development in diverse vertebrate species. To gain…”
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