Search Results - "Burbano, R.R"

Genomic and transcriptomic characterization of the human glioblastoma cell line AHOL1 by Ferreira, W A S, Amorim, C K N, Burbano, R R, Villacis, R A R, Marchi, F A, Medina, T S, Lima, M M C de, Oliveira, E H C de

“…Cancer cell lines are widely used as in vitro models of tumorigenesis, facilitating fundamental discoveries in cancer biology and translational medicine…”
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Genotoxic effects of aluminum chloride in cultured human lymphocytes treated in different phases of cell cycle by Lima, P.D.L., Leite, D.S., Vasconcellos, M.C., Cavalcanti, B.C., Santos, R.A., Costa-Lotufo, L.V., Pessoa, C., Moraes, M.O., Burbano, R.R.

“…Aluminum (Al) is the most abundant metal and the third common chemical element on earth. It is known that Al is toxic, especially its trivalent form (Al 3+),…”
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PREVALÊNCIA DO VÍRUS DA DENGUE, ZIKA E CHIKUNGUNYA EM DOADORES DE SANGUE NA REGIÃO METROPOLITANA DE BELÉM by L.N. Lopes, P.M. Jordão, M.S.M. Lima, A.N.D. Santos, N.C. Almeida, A.S.M. Corrêa, M.P. Koury, R.B.H. Castro, R.R. Burbano, L.M. Lamarão

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Genotoxicity evaluation of kaurenoic acid, a bioactive diterpenoid present in Copaiba oil by Cavalcanti, B.C., Costa-lotufo, L.V., Moraes, M.O., Burbano, R.R., Silveira, E.R., Cunha, K.M.A., Rao, V.S.N., Moura, D.J., Rosa, R.M., Henriques, J.A.P., Pessoa, C.

“…Copaiba oil extracted from the Amazon traditional medicinal plant Copaifera langsdorffii is rich in kaurenoic acid (ent-kaur-16-en-19-oic acid), a diterpene…”
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Cytogenetic characterization and evaluation of c-MYC gene amplification in PG100, a new Brazilian gastric cancer cell line by Ribeiro, H F, Alcântara, D F A, Matos, L A, Sousa, J M C, Leal, M F, Smith, M A C, Burbano, R R, Bahia, M O

“…Gastric cancer is the fourth most frequent type of cancer and the second cause of cancer mortality worldwide. The genetic alterations described so far for…”
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Cytotoxicity and genotoxicity of low doses of mercury chloride and methylmercury chloride on human lymphocytes in vitro by Silva-Pereira, L C, Cardoso, P C S, Leite, D S, Bahia, M O, Bastos, W R, Smith, M A C, Burbano, R R

“…Mercury is a xenobiotic metal that is a highly deleterious environmental pollutant. The biotransformation of mercury chloride (HgCl2) into methylmercury…”
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Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer by Lima, E M, Leal, M F, Burbano, R R, Khayat, A S, Assumpção, P P, Bello, M J, Rey, J A, Smith, M A C, Casartelli, C

“…Gastric cancer is the forth most frequent malignancy and the second most common cause of cancer death worldwide. DNA methylation is the most studied epigenetic…”
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Prognostic value of TP53 Pro47Ser and Arg72Pro single nucleotide polymorphisms and the susceptibility to gliomas in individuals from Southeast Brazil by Pinto, G R, Yoshioka, F K N, Silva, R L L, Clara, C A, Santos, M J, Almeida, J R W, Burbano, R R, Rey, J A, Casartelli, C

“…The TP53 tumor suppressor gene codifies a protein responsible for preventing cells with genetic damage from growing and dividing by blocking cell growth or…”
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Conventional cytogenetic characterization of a new cell line, ACP01, established from a primary human gastric tumor by Lima, E M, Rissino, J D, Harada, M L, Assumpção, P P, Demachki, S, Guimarães, A C, Casartelli, C, Smith, M A C, Burbano, R R

“…Gastric cancer is the second most frequent type of neoplasia and also the second most important cause of death in the world. Virtually all the established cell…”
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TP53 codon 72 polymorphism as a risk factor for cardiovascular disease in a Brazilian population by Smith, M A C, Silva, M D A, Cendoroglo, M S, Ramos, L R, Araujo, L M Q, Labio, R W, Burbano, R R, Chen, E S, Payão, S L M

“…TP53, a tumor suppressor gene, has a critical role in cell cycle, apoptosis and cell senescence and participates in many crucial physiological and pathological…”
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Frequency of Werner helicase 1367 polymorphism and age-related morbidity in an elderly Brazilian population by Smith, M A C, Silva, M D A, Araujo, L Q, Ramos, L R, Labio, R W, Burbano, R R, Peres, C A, Andreoli, S B, Payão, S L M, Cendoroglo, M S

“…Werner syndrome (WS) is a premature aging disease caused by a mutation in the WRN gene. The gene was identified in 1996 and its product acts as a DNA helicase…”
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Cytogenetic description of breast fibroadenomas: alterations related solely to proliferation? by Burbano, R R, Lima, E M, Khayat, A S, Barbieri Neto, J, Cabral, I R, Bastos, Jr, L, Bahia, M O, Casartelli, C

“…Twelve breast fibroadenomas were analyzed cytogenetically and only four were found to have clonal alterations. The presence of chromosomal alterations in…”
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Investigation of single-strand conformational polymorphism of the TP53 gene in women with a family history of breast cancer by Burbano, R R, Medeiros, A C, Mello, A A, Lemos, J A, Bahia, M O, Casartelli, C

“…Breast cancer in families with germ line mutations in the TP53 gene has been described in the medical literature. Mutation screening for susceptibility genes…”
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Prevalence of CCR5-Δ32 and CCR2-V64I polymorphisms in a mixed population from northeastern Brazil by Ferreira-Fernandes, H, Santos, A C C, Motta, F J N, Canalle, R, Yoshioka, F K N, Burbano, R R, Rey, J A, da Silva, B B, Pinto, G R

“…Chemokines are low-molecular weight proteins that play a key role in inflammatory processes. Genomic variations in chemokine receptors are associated with the…”
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Short Communication Association of APOA1 and APOA5 polymorphisms and haplotypes with lipid parameters in a Brazilian elderly cohort by Furuya, T.K., Chen, E.S., Ota, V.K., Mazzotti, D.R., Ramos, L.R., Cendoroglo, M.S., Araujo, L.Q., Burbano, R.R., Smith, M.A.C.

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Structure–mutagenicity relationship of kaurenoic acid from Xylopia sericeae (Annonaceae) by Cavalcanti, B.C., Ferreira, J.R.O., Moura, D.J., Rosa, R.M., Furtado, G.V., Burbano, R.R., Silveira, E.R., Lima, M.A.S., Camara, C.A.G., Saffi, J., Henriques, J.A.P., Rao, V.S.N., Costa-Lotufo, L.V., Moraes, M.O., Pessoa, C.

“…Kaurane diterpenes are considered important compounds in the development of new highly effective anticancer chemotherapeutic agents. Genotoxic effects of…”
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Association of the rs7903146 and rs12255372 polymorphisms in the TCF7L2 gene with type 2 diabetes in a population from northeastern Brazil by Barros, C M A R, Araujo-Neto, A P, Lopes, T R, Barros, M A L, Motta, F J N, Canalle, R, Nunes, L C C, Rey, J A, Burbano, R R, Lima-Barros, M A, Yoshioka, F K N, Pinto, G R

“…Approximately 200 million people suffer from type 2 diabetes (T2D) worldwide, and the rapid increase in the prevalence of this disease is likely a result of…”
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Genotoxic and cytotoxic effects of manganese chloride in cultured human lymphocytes treated in different phases of cell cycle by Lima, P.D.L., Vasconcellos, M.C., Bahia, M.O., Montenegro, R.C., Pessoa, C.O., Costa-Lotufo, L.V., Moraes, M.O., Burbano, R.R.

“…Manganese (Mn) has a natural occurrence and is necessary during the initial periods of the development. However, in high concentrations, Mn can be related to…”
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Cellular responses induced in vitro by iron (Fe) in a central nervous system cell line (U343MGa) by Alcântara, D D F A, Ribeiro, H F, Matos, L A, Sousa, J M C, Burbano, R R, Bahia, M O

“…Iron is the most important metallic chemical element on Earth. Poisoning caused by excessive iron in humans has been associated with pulmonary diseases…”
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Cellular responses induced in vitro by pestheic acid, a fungal metabolite, in a gastric adenocarcinoma cell line (PG100) by Sousa, J M C, Matos, L A, Alcântara, D F A, Ribeiro, H F, Santos, L S, Oliveira, M N, Brito-Junior, L C, Khayat, A S, Guimarães, A C, Cunha, L A, Burbano, R R, Bahia, M O

“…There is a constant search for new cancer treatments that are less aggressive and economically affordable. In this context, natural products extracted from…”
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