Clinical studies with the NOVA ISE for IMg2

The Nova ISE for IMg2+ was utilized to examine IMg2+ in plasma and serum of patients with a variety of pathophysiologic and disease syndromes (e.g., long-term renal transplants [LTRT], during and before cardiac surgery, migraine headaches, head trauma, pregnancy, chronic fatigue syndrome [CFS], non-...

Full description

Saved in:

Bibliographic Details
Published in:	Scandinavian journal of clinical & laboratory investigation. Supplement Vol. 217; p. 53
Main Authors:	Altura, B T, Burack, J L, Cracco, R Q, Galland, L, Handwerker, S M, Markell, M S, Mauskop, A, Memon, Z S, Resnick, L M, Zisbrod, Z
Format:	Journal Article
Language:	English
Published:	Norway 1994
Subjects:	Calcium - blood Critical Care Disease Female Humans Ion-Selective Electrodes Magnesium - blood Male Pregnancy
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The Nova ISE for IMg2+ was utilized to examine IMg2+ in plasma and serum of patients with a variety of pathophysiologic and disease syndromes (e.g., long-term renal transplants [LTRT], during and before cardiac surgery, migraine headaches, head trauma, pregnancy, chronic fatigue syndrome [CFS], non-insulin dependent diabetes mellitus [NIDDM], asthma and after excessive dietary intake of Mg). The results indicate that LTRT treated with cyclosporin A, migraine, head trauma, pregnancy, NIDDM, diseased pregnant, and asthmatic patients all on the average, exhibit significant depression in IMg2+ but not total Mg (TMg). Patients with CFS failed to exhibit changes in serum IMg2+ or TMg levels. Increased dietary load of Mg, for only 6 days, resulted in significant elevations of serum IMg2+ but not TMg. Correlations between the clinical course of several of these syndromes and the fall in IMg2+ were found. The Ca2+/Mg2+ ratio appears to be an important guide for signs of peripheral vasoconstriction and or spasm and possibly enhanced atherogenesis. Overall, the data point to important uses for ISE's for IMg2+ in the diagnosis and treatment of disease states.
ISSN:	0085-591X
DOI:	10.3109/00365519409095211