Search Results - "Bupp, Sujata"

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types by Doyle, Joseph P., Dougherty, Joseph D., Heiman, Myriam, Schmidt, Eric F., Stevens, Tanya R., Ma, Guojun, Bupp, Sujata, Shrestha, Prerana, Shah, Rajiv D., Doughty, Martin L., Gong, Shiaoching, Greengard, Paul, Heintz, Nathaniel

“…Comparative analysis can provide important insights into complex biological systems. As demonstrated in the accompanying paper, translating ribosome affinity…”
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A novel murine in vivo model for acute hereditary angioedema attacks by Bupp, Sujata, Whittaker, Matthew, Lehtimaki, Mari, Park, JuMe, Dement-Brown, Jessica, Zhou, Zhao-Hua, Kozlowski, Steven

“…Hereditary Angioedema (HAE) is a rare genetic disease generally caused by deficiency or mutations in the C1-inhibitor gene, SERPING1, a member of the Serpin…”
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Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer by SZABOVA, Ludmila, CHAOYING YIN, MCDUNN, Jonathan E, MARTIN, Philip L, VAN DYKE, Terry, DIFILIPPANTONIO, Simone, BUPP, Sujata, GUERIN, Theresa M, SCHLOMER, Jerome J, HOUSEHOLDER, Deborah B, BARAN, Maureen L, MING YI, YURONG SONG, WENPING SUN

“…The majority of human high-grade serous epithelial ovarian cancer (SEOC) is characterized by frequent mutations in p53 and alterations in the RB and FOXM1…”
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Phenotype-driven chemical screening in zebrafish for compounds that inhibit collective cell migration identifies multiple pathways potentially involved in metastatic invasion by Gallardo, Viviana E, Varshney, Gaurav K, Lee, Minnkyong, Bupp, Sujata, Xu, Lisha, Shinn, Paul, Crawford, Nigel P, Inglese, James, Burgess, Shawn M

“…In the last decade, high-throughput chemical screening has become the dominant approach for discovering novel compounds with therapeutic properties. Automated…”
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Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer by Szabova, Ludmila, Bupp, Sujata, Kamal, Muhaymin, Householder, Deborah B, Hernandez, Lidia, Schlomer, Jerome J, Baran, Maureen L, Yi, Ming, Stephens, Robert M, Annunziata, Christina M, Martin, Philip L, Van Dyke, Terry A, Weaver Ohler, Zoe, Difilippantonio, Simone

“…The high mortality rate from ovarian cancers can be attributed to late-stage diagnosis and lack of effective treatment. Despite enormous effort to develop…”
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Developing in vitro and in vivo Models to Predict Drug-Induced Acute Allergic Adverse Reactions by Zhou, Zhaohua, Bupp, Sujata, Hoang, Uyen, Kozlowski, Steven

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In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity α6 ∗ Nicotinic Acetylcholine Receptors by Drenan, Ryan M., Grady, Sharon R., Whiteaker, Paul, McClure-Begley, Tristan, McKinney, Sheri, Miwa, Julie M., Bupp, Sujata, Heintz, Nathaniel, McIntosh, J. Michael, Bencherif, Merouane, Marks, Michael J., Lester, Henry A.

“…α6-containing (α6 ∗) nicotinic ACh receptors (nAChRs) are selectively expressed in dopamine (DA) neurons and participate in cholinergic transmission. We…”
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Abstract 4952: Germline variation modulates susceptibility to aggressive disease development in a mouse model of prostate tumorigenesis by Williams, Kendra A., Bupp, Sujata, Patel, Shashank, Andreas, Jonathan, Zhang, Suiyuan, Molinolo, Alfredo, Gutkind, Silvio, Crawford, Nigel

“…Abstract Although prostate cancer is common, with over 238,000 new cases being diagnosed in the US in 2012, it typically runs an indolent course with most men…”
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Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc by Lee, Minnkyong, Beggs, Sarah M, Gildea, Derek, Bupp, Sujata, Lichtenberg, Jens, Trivedi, Niraj S, Hu, Ying, Bodine, David M, Crawford, Nigel P S

“…Metastasis is the primary cause of death in breast cancer. Earlier studies using a mammary tumorigenesis mouse model identified Necdin (Ndn)as a germline…”
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Abstract C21: A germline polymorphism in Necdin causes changes in gene expression and mammary tumor metastasis by Lee, Minnkyong, Beggs, Sarah M., Lichtenberg, Jens, Bupp, Sujata B., Trivedi, Niraj S., Hu, Ying, Bodine, David M., Crawford, Nigel P.S.

“…Abstract Necdin (NDN) is a transcription factor that regulates gene expression by cooperating with chromatin modifying factors. Earlier studies using mouse…”
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Aspirin insensitive thrombophilia: Transcript profiling of blood identifies platelet abnormalities and HLA restriction by Fallahi, Payam, Katz, Richard, Toma, Ian, Li, Ranyang, Reiner, Jonathan, VanHouten, Kiersten, Carpio, Larry, Marshall, Lorraine, Lian, Yi, Bupp, Sujata, Fu, Sidney W., Rickles, Frederick, Leitenberg, David, Lai, Yinglei, Weksler, Babette B., Rebling, Frederik, Yang, Zhaoqing, McCaffrey, Timothy A.

“…Aspirin is the most widely used antiplatelet agent because it is safe, efficient, and inexpensive. However, a significant subset of patients does not exhibit a…”
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Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types by Doyle, Joseph P., Dougherty, Joseph D., Heiman, Myriam, Schmidt, Eric F., Stevens, Tanya R., Ma, Guojun, Bupp, Sujata, Shrestha, Prerana, Shah, Rajiv D., Doughty, Martin L., Gong, Shiaoching, Greengard, Paul, Heintz, Nathaniel

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Application of BACarray for comparative analysis of CNS cell types by Doyle, Joseph P., Dougherty, Joseph D., Heiman, Myriam, Schmidt, Eric F., Stevens, Tanya R., Ma, Guojun, Bupp, Sujata, Shrestha, Prerana, Shah, Rajiv D., Doughty, Martin L., Gong, Shiaoching, Greengard, Paul, Heintz, Nathaniel

“…Comparative analysis of BACarray data can provide important insights into complex biological systems. As demonstrated in the accompanying paper, BACarray…”
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In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity alpha 6 super() Nicotinic Acetylcholine Receptors by Drenan, Ryan M, Grady, Sharon R, Whiteaker, Paul, McClure-Begley, Tristan, McKinney, Sheri, Miwa, Julie M, Bupp, Sujata, Heintz, Nathaniel, McIntosh, JMichael, Bencherif, Merouane, Marks, Michael J, Lester, Henry A

“…alpha 6-containing ( alpha 6 super(*)) nicotinic ACh receptors (nAChRs) are selectively expressed in dopamine (DA) neurons and participate in cholinergic…”
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In Vivo Activation of Midbrain Dopamine Neurons via Sensitized, High-Affinity [alpha]6[low ] Nicotinic Acetylcholine Receptors by Drenan, Ryan M, Grady, Sharon R, Whiteaker, Paul, McClure-Begley, Tristan, McKinney, Sheri, Miwa, Julie M, Bupp, Sujata, Heintz, Nathaniel, McIntosh, J Michael, Bencherif, Merouane, Marks, Michael J, Lester, Henry A

“…α6-containing (α6[low *]) nicotinic ACh receptors (nAChRs) are selectively expressed in dopamine (DA) neurons and participate in cholinergic transmission. We…”
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In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors by Drenan, Ryan M, Grady, Sharon R, Whiteaker, Paul, McClure-Begley, Tristan, McKinney, Sheri, Miwa, Julie M, Bupp, Sujata, Heintz, Nathaniel, McIntosh, J Michael, Bencherif, Merouane, Marks, Michael J, Lester, Henry A

“…Alpha6-containing (alpha6*) nicotinic ACh receptors (nAChRs) are selectively expressed in dopamine (DA) neurons and participate in cholinergic transmission. We…”
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