Search Results - "Buonanno, Andres"
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Selective populations of hippocampal interneurons express ErbB4 and their number and distribution is altered in ErbB4 knockout mice
Published in Hippocampus (01-06-2010)“…Neuregulins (NRGs) are ligands of ErbB receptor tyrosine kinases. The NRG1‐ErbB4 pathway has been shown to modulate hippocampal synaptic plasticity and network…”
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Correction to: NMDA Receptors Regulate Neuregulin 2 Binding to ER-PM Junctions and Ectodomain Release by ADAM10
Published in Molecular neurobiology (2020)“…The original version of this article unfortunately contained an error in Title as the authors inadvertently deleted during revisions the last two words of…”
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Presynaptic NMDA receptors also make the switch
Published in Nature neuroscience (01-03-2011)“…A study shows that NR3A–containing presynaptic NMDA receptors regulate glutamate release, and that a switch in subunit composition underlies the developmental…”
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Toxic and Phenotypic Effects of AAV_Cre Used to Transduce Mesencephalic Dopaminergic Neurons
Published in International journal of molecular sciences (21-08-2022)“…A popular approach to spatiotemporally target genes using the /Cre recombination system is stereotaxic microinjection of adeno-associated virus (AAV)…”
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ER-PM Junctions on GABAergic Interneurons Are Organized by Neuregulin 2/VAP Interactions and Regulated by NMDA Receptors
Published in International journal of molecular sciences (02-02-2023)“…Neuregulins (NRGs) signal via ErbB receptors to regulate neural development, excitability, synaptic and network activity, and behaviors relevant to psychiatric…”
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Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development
Published in Development (Cambridge) (01-11-2007)“…Specification of cell lineages in mammals begins shortly after fertilization with formation of a blastocyst consisting of trophectoderm, which contributes…”
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Neuregulin-1 Modulates Hippocampal Gamma Oscillations: Implications for Schizophrenia
Published in Cerebral cortex (New York, N.Y. 1991) (01-03-2009)“…Alterations in gamma-frequency oscillations are implicated in psychiatric disorders, and polymorphisms in NRG-1 and ERBB4, genes encoding Neuregulin-1 (NRG-1)…”
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Conserved Interneuron-Specific ErbB4 Expression in Frontal Cortex of Rodents, Monkeys, and Humans: Implications for Schizophrenia
Published in Biological psychiatry (1969) (01-10-2011)“…Background Neuregulin-1 and ErbB4 are genetically associated with schizophrenia, and detailed knowledge of the cellular and subcellular localization of ErbB4…”
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Neuronal correlates of ketamine and walking induced gamma oscillations in the medial prefrontal cortex and mediodorsal thalamus
Published in PloS one (02-11-2017)“…Alterations in the function of the medial prefrontal cortex (mPFC) and its major thalamic source of innervation, the mediodorsal (MD) thalamus, have been…”
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Disruption of the ErbB signaling in adolescence increases striatal dopamine levels and affects learning and hedonic-like behavior in the adult mouse
Published in European neuropsychopharmacology (01-11-2014)“…Abstract The ErbB signaling pathway has been genetically and functionally implicated in schizophrenia. Numerous findings support the dysregulation of…”
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Neuregulin directly decreases voltage-gated sodium current in hippocampal ErbB4-expressing interneurons
Published in The Journal of neuroscience (03-10-2012)“…The Neuregulin 1 (NRG1)/ErbB4 signaling pathway has been genetically and functionally implicated in the etiology underlying schizophrenia, and in the…”
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Neuregulin and dopamine modulation of hippocampal gamma oscillations is dependent on dopamine D4 receptors
Published in Proceedings of the National Academy of Sciences - PNAS (07-08-2012)“…The neuregulin/ErbB signaling network is genetically associated with schizophrenia and modulates hippocampal γ oscillations—a type of neuronal network activity…”
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Neuregulin and ErbB receptor signaling pathways in the nervous system
Published in Current Opinion in Neurobiology (01-06-2001)“…The neuregulins are a complex family of factors that perform many functions during neural development. Recent experiments have shown that neuregulins promote…”
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Neuregulin-1 regulates LTP at CA1 hippocampal synapses through activation of dopamine D4 receptors
Published in Proceedings of the National Academy of Sciences - PNAS (07-10-2008)“…Neuregulin-1 (NRG-1) is genetically linked with schizophrenia, a neurodevelopmental cognitive disorder characterized by imbalances in glutamatergic and…”
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Behavioral analysis of NR2C knockout mouse reveals deficit in acquisition of conditioned fear and working memory
Published in Neurobiology of learning and memory (01-05-2011)“…► NR2C knockout mice exhibit deficit in cued and contextual fear conditioning. ► Conditioning-induced thalamo-amygdala synaptic strengthening is absent in NR2C…”
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NR2C in the thalamic reticular nucleus; effects of the NR2C knockout
Published in PloS one (25-07-2012)“…NMDAR antagonists can evoke delta frequency bursting in the nucleus reticularis of the thalamus (nRT). The mechanism of this oscillation was determined;…”
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The neuregulin signaling pathway and schizophrenia: From genes to synapses and neural circuits
Published in Brain research bulletin (30-09-2010)“…Abstract Numerous genetic linkage and association studies implicate members of the Neuregulin-ErbB receptor (NRG-ErbB) signaling pathway as schizophrenia “at…”
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Neuregulin-1 Reverses Long-Term Potentiation at CA1 Hippocampal Synapses
Published in The Journal of neuroscience (12-10-2005)“…Neuregulin-1 (NRG-1) has been identified genetically as a schizophrenia susceptibility gene, but its function in the adult brain is unknown. Here, we show that…”
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ErbB4 reduces synaptic GABAA currents independent of its receptor tyrosine kinase activity
Published in Proceedings of the National Academy of Sciences - PNAS (26-11-2013)“…ErbB4 signaling in the central nervous system is implicated in neuropsychiatric disorders and epilepsy. In cortical tissue, ErbB4 associates with excitatory…”
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ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors
Published in eNeuro (01-05-2020)“…Natural genetic variants of Neuregulin1 (NRG1) and its cognate receptor ErbB4 are associated with a risk for schizophrenia. Whereas most studies on NRG1-ErbB4…”
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