A brief case series of radiation associated myelopathy

Radiation myelopathy (RM) is a rare but serious complication of radiotherapy. Small vessel ischemia and demyelination are some of the more remarkable indications of RM's pathophysiology. The RM is a diagnosis of exclusion. In the differential diagnosis, infectious causes, tumors, rheumatic dise...

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Bibliographic Details
Published in:Neurosciences (Riyadh, Saudi Arabia) Vol. 26; no. 4; pp. 392 - 395
Main Authors: Bunul, Sena D, Sarikaya, Cansu E, Ozturk, Onural, Sarikaya, Caner
Format: Journal Article
Language:English
Published: Saudi Arabia Saudi Medical Journal 01-10-2021
Riyadh : Armed Forces Hospital
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Summary:Radiation myelopathy (RM) is a rare but serious complication of radiotherapy. Small vessel ischemia and demyelination are some of the more remarkable indications of RM's pathophysiology. The RM is a diagnosis of exclusion. In the differential diagnosis, infectious causes, tumors, rheumatic diseases, and paraneoplastic syndromes are the main diseases that should be excluded. Contrast-enhanced magnetic resonance imaging (MRI) is a useful method for diagnosis. We present a report on 3 patients diagnosed with radiation myelitis. All the patients presented with late paraparasia and paresthesia. Despite high-dose steroids, hyperbaric oxygen, and physical therapy, there was no clinical improvement at the follow-up one year later.
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ISSN:1319-6138
1319-6138
DOI:10.17712/nsj.2021.4.20210071