Search Results - "Bunting, T."

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    Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment by Dong, Lei, Yu, Wen-Mei, Zheng, Hong, Loh, Mignon L., Bunting, Silvia T., Pauly, Melinda, Huang, Gang, Zhou, Muxiang, Broxmeyer, Hal E., Scadden, David T., Qu, Cheng-Kui

    Published in Nature (London) (10-11-2016)
    “…Mutations in the protein tyrosine phosphatase SHP2 affect cells in the bone marrow environment, which leads to aberrant activation of resident haematopoietic…”
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    Journal Article
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    Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8 + T-Cell Activation by Wang, Zhengqi, Vaughan, Tamisha Y, Zhu, Wandi, Chen, Yuhong, Fu, Guoping, Medrzycki, Magdalena, Nishio, Hikaru, Bunting, Silvia T, Hankey-Giblin, Pamela A, Nusrat, Asma, Parkos, Charles A, Wang, Demin, Wen, Renren, Bunting, Kevin D

    Published in Frontiers in immunology (18-03-2019)
    “…Inflammatory Bowel Disease (IBD) is a multi-factorial chronic inflammation of the gastrointestinal tract prognostically linked to CD8 T-cells, but little is…”
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    Utility of Fluorescence In Situ Hybridization Panel for Myelodysplastic Syndrome in Evaluation of Cytopenia in a Pediatric Hospital: A 5-Year Retrospective Review and Utilization Management by Bunting, Cynthia T, Senior, Tal, Susson, Yehuda, Rivera, Alethia, Saxe, Debra, Bunting, Silvia T

    Published in Laboratory medicine (01-08-2017)
    “…Abstract Background MDS FISH was routinely ordered together with chromosome analysis for patients with cytopenia in our hospital. The utility of MDS FISH in…”
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    Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia by Raikar, Sunil S., Scarborough, John D., Sabnis, Himalee, Bergsagel, John, Wu, David, Cooper, Todd M., Keller, Frank G., Wood, Brent L., Bunting, Silvia T.

    Published in Pediatric blood & cancer (01-09-2016)
    “…Early T‐cell precursor acute lymphoblastic leukemia (ETP‐ALL) is a subtype of T‐acute lymphoblastic leukemia (T‐ALL) arising from a primitive precursor. We…”
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    Specific inhibition of ectodomain shedding of glycoprotein Ibα by targeting its juxtamembrane shedding cleavage site by Liang, X., Russell, S. R., Estelle, S., Jones, L. H., Cho, S., Kahn, M. L., Berndt, M. C., Bunting, S. T., Ware, J., Li, R.

    Published in Journal of thrombosis and haemostasis (01-12-2013)
    “…Summary Background Ectodomain shedding of glycoprotein Ibα (GPIbα), a proteolytic event in which metalloprotease ADAM17 cleaves the Gly464‐Val465 bond and…”
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    Acute Myeloid Leukemia in an Infant with t(8;19)(p11.2;q13) Translocation: Case Report and a Review of the Literature by Saxe, Debra, Peterson, Jess F., Bunting, Silvia T., Eason, Ashley C., Sabnis, Himalee S.

    Published in Case reports in hematology (08-09-2019)
    “…Acute myeloid leukemia (AML) patients with t(8;16)(p11.2;p13) constitute a small subgroup with a distinct genetic and clinical profile. We present a unique…”
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    Splenic marginal zone lymphoma with prolymphocytic transformation and cyclin D1 expression in the absence of CCND1 rearrangement by Elbaz Younes, Ismail, Bunting, Silvia T, Zhang, Xiaohui

    Published in International journal of hematology (16-09-2024)
    “…Splenic marginal zone lymphoma (SMZL) is one of the most common B-cell lymphomas that affect the spleen. We report a case with splenomegaly and lymphocytosis…”
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    Density Gradients in Canadian Metropolitan Regions, 1971-96: Differential Patterns of Central Area and Suburban Growth and Change by Bunting, T., Filion, P., Priston, H.

    Published in Urban studies (Edinburgh, Scotland) (01-12-2002)
    “…This paper demonstrates that over the 25-year period, 1971-96, the majority of Canadian cities have undergone transition towards an increasingly decentralised…”
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    Stat5-deficient hematopoiesis is permissive for Myc-induced B-cell leukemogenesis by Wang, Zhengqi, Medrzycki, Magdalena, Bunting, Silvia T, Bunting, Kevin D

    Published in Oncotarget (06-10-2015)
    “…Despite being an attractive molecular target for both lymphoid and myeloid leukemias characterized by activated tyrosine kinases, the molecular and…”
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  13. 13

    A variant c‐KIT mutation, D816H, fundamental to the sequential development of an ovarian mixed germ cell tumor and systemic mastocytosis with chronic myelomonocytic leukemia by Mitchell, Sarah G., Bunting, Silvia T., Saxe, Debra, Olson, Thomas, Keller, Frank G.

    Published in Pediatric blood & cancer (01-04-2017)
    “…An activating point mutation of the c‐KIT tyrosine kinase receptor gene, D816H, has been described in germ cell tumors (GCTs). We report an adolescent…”
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    Capillary nano-immunoassay for Akt 1/2/3 and 4EBP1 phosphorylation in acute myeloid leukemia by Sabnis, Himalee, Bradley, Heath L, Bunting, Silvia T, Cooper, Todd M, Bunting, Kevin D

    Published in Journal of translational medicine (12-06-2014)
    “…Overall cure rates in acute myeloid leukemia (AML) continue to range between 60-65% with disease relapse being a major cause of mortality. The PI3K-Akt-mTOR…”
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    Regulation of Insulin-Like Growth Factor I (IGF-I) Gene Expression in Brain of Transgenic Mice Expressing an IGF-I-Luciferase Fusion Gene by Ye, P., Umayahara, Y., Ritter, D., Bunting, T., Auman, H., Rotwein, P., D’Ercole, A. J.

    Published in Endocrinology (Philadelphia) (01-12-1997)
    “…Abstract Insulin-like growth factor I (IGF-I) plays an important role in the development and function of the central nervous system (CNS). Little is known,…”
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