Search Results - "Bunting, Kristopher"
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CARMN Is an Evolutionarily Conserved Smooth Muscle Cell–Specific LncRNA That Maintains Contractile Phenotype by Binding Myocardin
Published in Circulation (New York, N.Y.) (07-12-2021)“…Vascular homeostasis is maintained by the differentiated phenotype of vascular smooth muscle cells (VSMCs). The landscape of protein coding genes comprising…”
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Long noncoding RNA NEAT1 (nuclear paraspeckle assembly transcript 1) is critical for phenotypic switching of vascular smooth muscle cells
Published in Proceedings of the National Academy of Sciences - PNAS (11-09-2018)“…In response to vascular injury, vascular smooth muscle cells (VSMCs) may switch from a contractile to a proliferative phenotype thereby contributing to…”
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Emotional state alters encoding of long-term spatial episodic memory
Published in Neurobiology of learning and memory (01-01-2022)“…[Display omitted] The neurobiology of emotion and episodic memory are well-researched subjects, as is their intersection: memory of emotional events (i.e…”
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Light-Dark Open Field (LDOF): A novel task for sensitive assessment of anxiety
Published in Journal of neuroscience methods (01-11-2021)“…Pre-clinical studies of psychiatric disorders often include a measure of anxiety-like behavior. Several tasks exist that serve this purpose, but because…”
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Investigating Individual Pre-trauma Susceptibility to a PTSD-Like Phenotype in Animals
Published in Frontiers in systems neuroscience (14-01-2020)“…Post-Traumatic Stress Disorder (PTSD) is a complex condition that develops after experiencing a severe emotional trauma, with or without physical trauma. There…”
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Angiotensin receptor (AT2R) agonist C21 prevents cognitive decline after permanent stroke in aged animals—A randomized double- blind pre-clinical study
Published in Behavioural brain research (01-02-2019)“…•C21 reduced weight loss and enhanced recovery in aged rats post-stroke.•C21 preserved non-spatial and short-term working memory in aged rats post-stroke.•C21…”
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Role of angiotensin system modulation on progression of cognitive impairment and brain MRI changes in aged hypertensive animals – A randomized double- blind pre-clinical study
Published in Behavioural brain research (02-07-2018)“…•RAS modulators preserved cognition in aged SHRs with cerebral hypoperfusion.•C21 reduced accumulation of Aβ1-42 in the prefrontal cortex of aged SHRs.•C21…”
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Altered hippocampal function before emotional trauma in rats susceptible to PTSD-like behaviors
Published in Neurobiology of learning and memory (01-07-2014)“…Posttraumatic stress disorder (PTSD) is an anxiety disorder that occurs after experiencing a traumatic event. Susceptibility to PTSD exists, as only some…”
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Influence of Isoflurane on Immediate-Early Gene Expression
Published in Frontiers in behavioral neuroscience (12-01-2016)“…Anterograde amnesia is a hallmark effect of volatile anesthetics. Isoflurane is known to affect both the translation and transcription of plasticity-associated…”
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Predicting impaired extinction of traumatic memory and elevated startle
Published in PloS one (18-05-2011)“…Emotionally traumatic experiences can lead to debilitating anxiety disorders, such as phobias and Post-Traumatic Stress Disorder (PTSD). Exposure to such…”
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Encoding of emotion-paired spatial stimuli in the rodent hippocampus
Published in Frontiers in behavioral neuroscience (14-06-2012)“…Rats can acquire the cognitive component of CS-US associations between sensory and aversive stimuli without a functional basolateral amygdala (BLA). Thus,…”
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CARMN is an Evolutionarily Conserved Smooth Muscle Cell-specific LncRNA that Maintains Contractile Phenotype by Binding Myocardin
Published in Circulation (New York, N.Y.) (08-11-2021)Get full text
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Abstract TP89: Angiotensin Receptor (AT2R) Agonist C21 Accelerates Cognitive Functional Recovery After Permanent Stroke in Aged Animals
Published in Stroke (1970) (22-01-2018)“…Abstract only Background and objectives: Post stroke cognitive impairment (PSCI) is an understudied, long-term complication of stroke, impacting nearly 30-40%…”
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Tone identification behavior in Rattus norvegicus: muscarinic receptor blockage lowers responsiveness in nontarget selective neurons, while nicotinic receptor blockage selectively lowers target responses
Published in The European journal of neuroscience (01-07-2017)“…Learning to associate a stimulus with reinforcement causes plasticity in primary sensory cortex. Neural activity caused by the associated stimulus is paired…”
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Calcyon Up-regulation in Adolescence Impairs Response Inhibition and Working Memory in Adulthood
Published in Molecular psychiatry (15-03-2011)“…Calcyon regulates activity dependent internalization of AMPA glutamate receptors and long term depression of excitatory synapses. Elevated levels of calcyon…”
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