Search Results - "Bunte, Thomas"
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Thermally induced degradation pathways of three different antibody-based drug development candidates
Published in European journal of pharmaceutical sciences (01-10-2014)“…[Display omitted] Protein-based medicinal products are prone to undergo a variety of chemical and physical degradation pathways. One of the most important…”
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A new bioassay for the immunocytokine L19-IL2 for simultaneous analysis of both functional moieties
Published in Journal of pharmaceutical and biomedical analysis (01-01-2011)“…Currently, cancer directed new biological entities (NBEs) in the pharmaceutical R&D pipelines are derived from monoclonal antibodies in various formats, such…”
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3
Rapid diagnostic method for quantitative testing of <100 microbes in water
Published in PDA journal of pharmaceutical science and technology (01-09-2007)“…A robust, real-time polymerase chain reaction (RT-PCR) system to universally detect microbes at a limit of 10 to 50 colony-forming units within 5-6 h was…”
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Apolipoprotein E2/E2 genotype in combination with mutations in the LDL receptor gene causes type III hyperlipoproteinemia
Published in Clinical chemistry and laboratory medicine (01-05-2002)“…The primary genetic cause of type III hyperlipoproteinemia is the homozygous presence of the apolipoprotein E2 allele. However, only approximately 1% of…”
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The significance of high levels of lipoprotein (a) compared with established risk factors in premature coronary artery disease: differences between men and women
Published in Atherosclerosis (01-05-1999)“…It was shown in a series of studies that increased lipoprotein (a) concentration is a strong and independent risk factor for coronary artery disease. The goal…”
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6
Undulin, an extracellular matrix glycoprotein associated with collagen fibrils
Published in The Journal of biological chemistry (25-05-1990)“…Undulin, a novel noncollagenous extracellular matrix protein, was isolated from skin and placenta. In polyacrylamide gels most of the unreduced protein…”
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7
Influence of restricted food intake on estrous cycles and pseudopregnancies in dogs
Published in American journal of veterinary research (01-07-1999)“…To examine effects of restricted food intake on estrous cycle frequency, interestrus interval, and pseudopregnancy prevalence in dogs. 28 female Labrador…”
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DNA-binding activity is associated with purified myb proteins from AMV and E26 viruses and is temperature-sensitive for E26 ts mutants
Published in Cell (01-04-1985)“…Oncogene protein products from avian myeloblastosis virus, p48v-myb, and from avian leukemia virus E26, p135gag-myb-ets, are located predominantly in the…”
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9
Progression and regression of minor coronary arterial narrowings by quantitative angiography after fenofibrate therapy
Published in The American journal of cardiology (01-05-1991)“…To study the effects of fenofibrate, a lipid-lowering medication, on patients with coronary artery disease, 191 minor coronary narrowings in 42 patients with…”
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Effects of fenofibrate on angiographically examined coronary atherosclerosis and left ventricular function in hypercholesterolemic patients
Published in Atherosclerosis (25-01-1993)“…Within the framework of a prospective lipid-lowering intervention study 44 patients were treated over a period of 3 years with a lipid-lowering diet and…”
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Decreased DNA-binding ability of purified transformation-specific proteins from deletion mutants of the acute avian leukemia virus MC29
Published in Proceedings of the National Academy of Sciences - PNAS (01-05-1983)“…Avian myelocytomatosis virus MC29 is a highly oncogenic replication-defective retrovirus that predominantly affects hematopoietic cells and causes acute…”
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Simple repetitive DNA sequences are transcribed in early embryonal stages of Xenopus laevis
Published in DNA sequence (1994)“…We have isolated and sequenced three cDNA clones from early embryonal stages of Xenopus laevis containing highly repetitive sequences. By means of poly A+ RNA…”
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13
Analysis of Two Phosphoproteins Related to pp60src from Schmidt-ruppin D Virus Particles
Published in Journal of general virology (01-03-1983)“…Max-Planck-Institut für Molekulare Genetik, Ihnestrasse 63-73, D-1000 Berlin 33, F.R.G. During endogenous phosphorylation of partially purified pp60 src from…”
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