Search Results - "Bunkowski, S."

Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation by Bitsch, A, Schuchardt, J, Bunkowski, S, Kuhlmann, T, Brück, W

“…Damage to axons is taken as a key factor of disability in multiple sclerosis, but its pathogenesis is largely unknown. Axonal injury is believed to occur as a…”
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HIV encephalopathy: glial activation and hippocampal neuronal apoptosis, but limited neural repair by Tauber, SC, Staszewski, O, Prinz, M, Weis, J, Nolte, K, Bunkowski, S, Brück, W, Nau, R

“…Objectives HIV infection affects the central nervous system (CNS), frequently causing cognitive impairment. Hippocampal injury impedes the ability to transfer…”
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P-320: Course of Streptococcus pneumoniae meningitis in young and aged mice by Schütze, S, Manig, A, Ribes, S, Bunkowski, S, Nau, R

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Septic metastatic encephalitis: coexistence of brain damage and repair by Tauber, S. C., Bunkowski, S., Brück, W., Nau, R.

“…S. C. Tauber, S. Bunkowski, W. Brück and R. Nau (2011) Neuropathology and Applied Neurobiology37, 768–776 Septic metastatic encephalitis: coexistence of brain…”
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Oligodendrocyte and axon pathology in clinically silent multiple sclerosis lesions by Mews, I, Bergmann, M, Bunkowski, S, Gullotta, F, Brück, W

“…Oligodendrocyte and axon pathology was studied in 11 autopsy cases of clinically silent multiple sclerosis. A total of 54 lesions, either demyelinated or late…”
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S100B in the cerebrospinal fluid—A marker for glial damage in the rabbit model of pneumococcal meningitis by Schmidt, H., Gerber, J., Stuertz, K., Djukic, M., Bunkowski, S., Fischer, F.R., Otto, M., Nau, R.

“…The rabbit model provides an important experimental setting for the evaluation of antibiotic agents against pneumococcal meningitis. One of the primary targets…”
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Decreased serum levels of IL-6 and KC and faster clinical decline in aged mice during the acute phase of E. coli meningitis by Schütze, S, Manig, A, Ribes, S, Bunkowski, S, Nau, R

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Evidence for frequent focal and diffuse acute axonal injury in human bacterial meningitis by Gerber, J, Seitz, R-C, Bunkowski, S, Brück, W, Nau, R

“…We aimed at quantifying acute axonal injury in victims of bacterial meningitis. The brains of 26 autopsies with bacterial meningitis and of 10 control cases…”
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Lesion development in Marburg's type of acute multiple sclerosis: from inflammation to demyelination by Bitsch, A, Wegener, C, da Costa, C, Bunkowski, S, Reimers, C D, Prange, H W, Brück, W

“…We report a patient who suffered from acute inflammatory CNS demyelination and underwent two consecutive diagnostic stereotactic brain biopsies during the…”
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Follistatin (FS) in human cerebrospinal fluid and regulation of FS expression in a mouse model of meningitis by MICHEL, Uwe, EBERT, Sandra, SCHNEIDER, Olaf, SHINTANI, Yasumi, BUNKOWSKI, Stefanie, SMIRNOV, Alexandr, STRINGARIS, Argyrios K, GERBER, Joachim, BRÜCK, Wolfgang, NAU, Roland

“…Follistatin (FS) is the specific binding protein of activin and expression of both factors is regulated by inflammatory agents. Therefore, FS concentrations…”
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Lesion development in Marburg's type of acute multiple sclerosis: from inflammation to demyelination by Bitsch, A., Wegener, C., da Costa, C., Bunkowski, S., Reimers, C.D., Prange, H.W., Brück, W.

“…We report a patient who suffered from acute inflammatory CNS demyelination and underwent two consecutive diagnostic stereotactic brain biopsies during the…”
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Fungal encephalitis in human autopsy cases is associated with extensive neuronal damage but only minimal repair by Tauber, Simone C., Eiffert, Helmut, Kellner, Silvia, Lugert, Raimond, Bunkowski, Stephanie, Schütze, Sandra, Perske, Christina, Brück, Wolfgang, Nau, Roland

“…Aims The present study aimed at examining neuronal injury and repair in post mortem brain sections of humans who died from fungal central nervous system…”
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Axonal injury, a neglected cause of CNS damage in bacterial meningitis by NAU, Roland, GERBER, Joachim, BUNKOWSKI, Stephanie, BRÜCK, Wolfgang

“…The contribution of axonal injury to CNS damage in bacterial meningitis was studied by histology and immunohistochemistry for amyloid-beta precursor protein in…”
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Increased mortality and spatial memory deficits in TNF-α-deficient mice in ceftriaxone-treated experimental pneumococcal meningitis by Gerber, Joachim, Böttcher, Tobias, Hahn, Michael, Siemer, Alexander, Bunkowski, Stephanie, Nau, Roland

“…Tumor necrosis factor-α (TNF-α) is critically involved in inflammation and may participate in hippocampal injury in bacterial meningitis. In a mouse model of…”
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Tumour necrosis factor alpha mRNA expression in early multiple sclerosis lesions: Correlation with demyelinating activity and oligodendrocyte pathology by Bitsch, Andreas, Kuhlmann, Tanja, Da Costa, Christiane, Bunkowski, Stephanie, Polak, Thomas, Brück, Wolfgang

“…The precise role of tumour necrosis factor alpha (TNFα) in multiple sclerosis (MS) is still controversial. Most findings from the animal model experimental…”
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Rifampin Followed by Ceftriaxone for Experimental Meningitis Decreases Lipoteichoic Acid Concentrations in Cerebrospinal Fluid and Reduces Neuronal Damage in Comparison to Ceftriaxone Alone by GERBER, Joachim, POHL, Karin, SANDER, Valeska, BUNKOWSKI, Stephanie, NAU, Roland

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Decreased Virulence of a Pneumolysin-Deficient Strain of Streptococcus pneumoniae in Murine Meningitis by WELLMER, Andreas, ZYSK, Gregor, GERBER, Joachim, KUNST, Tammo, VON MERING, Matthias, BUNKOWSKI, Stefanie, EIFFERT, Helmut, NAU, Roland

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Clindamycin is neuroprotective in experimental Streptococcus pneumoniae meningitis compared with ceftriaxone by Böttcher, Tobias, Ren, Hao, Goiny, Michel, Gerber, Joachim, Lykkesfeldt, Jens, Kuhnt, Ulrich, Lotz, Miriam, Bunkowski, Stephanie, Werner, Carola, Schau, Ingmar, Spreer, Annette, Christen, Stephan, Nau, Roland

“…In animal models of Streptococcus pneumoniae meningitis, rifampin is neuroprotective in comparison to ceftriaxone. So far it is not clear whether this can be…”
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Increased activin levels in cerebrospinal fluid of rabbits with bacterial meningitis are associated with activation of microglia by Michel, Uwe, Gerber, Joachim, E. O'Connor, Anne, Bunkowski, Stephanie, Brück, Wolfgang, Nau, Roland, Phillips, David J.

“…Activin, a member of the transforming growth factor superfamily, is upregulated in a number of inflammatory episodes such as septicemia and rheumatoid…”
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The relative number of macrophages/microglia expressing macrophage colony-stimulating factor and its receptor decreases in multiple sclerosis lesions by Werner, Katrin, Bitsch, Andreas, Bunkowski, Stephanie, Hemmerlein, Bernhard, Brück, Wolfgang

“…The activation of macrophages/microglia in multiple sclerosis (MS) lesions plays a central role in the effector phase of myelin breakdown. The precise patterns…”
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