Search Results - "Bunker, Eric N"
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Nix interacts with WIPI2 to induce mitophagy
Published in The EMBO journal (15-11-2023)“…Nix is a membrane-anchored outer mitochondrial protein that induces mitophagy. While Nix has an LC3-interacting (LIR) motif that binds to ATG8 proteins, it…”
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2
Suppression of α-catenin and adherens junctions enhances epithelial cell proliferation and motility via TACE-mediated TGF-α autocrine/paracrine signaling
Published in Molecular biology of the cell (15-02-2021)“…Sustained cell migration is essential for wound healing and cancer metastasis. The epidermal growth factor receptor (EGFR) signaling cascade is known to drive…”
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3
Bok regulates mitochondrial fusion and morphology
Published in Cell death and differentiation (01-12-2019)“…Bok (Bcl-2-related ovarian killer) is a member of the Bcl-2 protein family that governs the intrinsic apoptosis pathway, but the cellular role that Bok plays…”
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TNIP1 inhibits selective autophagy via bipartite interaction with LC3/GABARAP and TAX1BP1
Published in Molecular cell (16-03-2023)“…Mitophagy is a form of selective autophagy that disposes of superfluous and potentially damage-inducing organelles in a tightly controlled manner. While the…”
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Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers
Published in Nucleic acids research (28-02-2018)“…Abstract Histone deacetylase inhibitors (HDACIs) are known to alter gene expression by both up- and down-regulation of protein-coding genes in normal and…”
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Protocol for Analysis and Consolidation of TrackMate Outputs for Measuring Two-Dimensional Cell Motility using Nuclear Tracking
Published in Journal of visualized experiments (18-12-2021)“…Collective cellular migration plays a key role in many fundamental biological processes including development, wound healing, and cancer metastasis. To…”
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