Search Results - "Bunch, Donna O."

Glyceraldehyde 3-Phosphate Dehydrogenase-S, a Sperm-Specific Glycolytic Enzyme, Is Required for Sperm Motility and Male Fertility by Miki, Kiyoshi, Qu, Weidong, Goulding, Eugenia H., Willis, William D., Bunch, Donna O., Strader, Lillian F., Perreault, Sally D., Eddy, Edward M., O'Brien, Deborah A., Yanagimachi, Ryuzo

“…Although glycolysis is highly conserved, it is remarkable that several unique isozymes in this central metabolic pathway are found in mammalian sperm…”
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Expression of the spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase (GAPDS) in rat testis by Welch, Jeffrey E., Barbee, Randy R., Magyar, Patricia L., Bunch, Donna O., O'Brien, Deborah A.

“…The spermatogenic cell‐specific variant of glyceraldehyde 3‐phosphate dehydrogenase (GAPDS) has been cloned from a rat testis cDNA library and its pattern of…”
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Measuring Circulating Complement Activation Products in Myeloperoxidase– and Proteinase 3–Antineutrophil Cytoplasmic Antibody–Associated Vasculitis by Wu, Eveline Y., McInnis, Elizabeth A., Boyer‐Suavet, Sonia, Mendoza, Carmen E., Aybar, Lydia T., Kennedy, Kristin B., Poulton, Caroline J., Henderson, Candace D., Hu, Yichun, Hogan, Susan L., Hu, Peiqi, Xiao, Hong, Nachman, Patrick H., Jennette, J. Charles, Falk, Ronald J., Bunch, Donna O.

“…Objective There is accumulating evidence that complement activation is important in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV)…”
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Rituximab as an immunosuppressant in antineutrophil cytoplasmic antibody-associated vasculitis by McGregor, JulieAnne G, Hogan, Susan L, Kotzen, Elizabeth S, Poulton, Caroline J, Hu, Yichun, Negrete-Lopez, Roberto, Kidd, Jason M, Katsanos, Suzanne L, Bunch, Donna O, Nachman, Patrick H, Falk, Ronald J

“…Rituximab has been used in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) since 2003. Our objective was to describe outcomes and…”
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Gleaning relapse risk from B cell phenotype: decreased CD5+ B cells portend a shorter time to relapse after B cell depletion in patients with ANCA-associated vasculitis by Bunch, Donna O, Mendoza, Carmen E, Aybar, Lydia T, Kotzen, Elizabeth S, Colby, Kerry R, Hu, Yichun, Hogan, Susan L, Poulton, Caroline J, Schmitz, John L, Falk, Ronald J, Nachman, Patrick H, Pendergraft, William F, McGregor, JulieAnne G

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Human Glyceraldehyde 3‐Phosphate Dehydrogenase‐2 Gene Is Expressed Specifically in Spermatogenic Cells by WELCH, JEFFREY E, BROWN, PAULA L, O'BRIEN, DEBORAH A, MAGYAR, PATRICIA L, BUNCH, DONNA O, MORI, CHISATO, EDDY, EDWARD M

“…Although the process of glycolysis is highly conserved in eukaryotes, several glycolytic enzymes have unique structural or functional features in spermatogenic…”
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Deficits in Reproduction and Pro-Gonadotropin-Releasing Hormone Processing in Male Cpefat Mice by Srinivasan, Sudha, Bunch, Donna O, Feng, Yun, Rodriguiz, Ramona M, Li, Min, Ravenell, Roneka L, Luo, Guo X, Arimura, Akira, Fricker, Lloyd D, Eddy, Edward M, Wetsel, William C

“…Cpefat/fat mice are obese, diabetic, and infertile. These animals have a point mutation in carboxypeptidase E (CPE), an exopeptidase that removes C-terminal…”
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Similar CD19 dysregulation in two autoantibody-associated autoimmune diseases suggests a shared mechanism of B-cell tolerance loss by Culton, Donna A, Nicholas, Matilda W, Bunch, Donna O, Zhen, Quan Li, Kepler, Thomas B, Dooley, Mary Anne, Mohan, Chandra, Nachman, Patrick H, Clarke, Stephen H

“…: We report here that dysregulation of CD19, a coreceptor that augments B-cell receptor (BCR) signaling, occurs at two B-cell differentiative stages in…”
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Prevention of the Polycystic Ovarian Phenotype and Characterization of Ovulatory Capacity in the Estrogen Receptor-α Knockout Mouse by Couse, John F, Bunch, Donna O, Lindzey, Jonathan, Schomberg, David W, Korach, Kenneth S

“…Ovarian-derived estradiol plays a critical endocrine role in the regulation of gonadotropin synthesis and secretion from the hypothalamic-pituitary axis. In…”
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Maintenance of Tolerance by Regulation of Anti-myeloperoxidase B Cells by BUNCH, Donna O, SILVER, Jonathan S, NACHMAN, Patrick H, MAJURE, Melanie C, SULLIVAN, Pamela, ALCORTA, David A, CHIN, Hyunsook, HOGAN, Susan L, LINDSTROM, Yoshi I, CLARKE, Stephen H, FALK, Ronald J

“…Anti-neutrophil cytoplasmic autoantibodies directed toward myeloperoxidase or proteinase 3 are detected in sera of patients with small vessel vasculitis and…”
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Brca1 and Brca2 expression patterns in mitotic and meiotic cells of mice by Blackshear, P E, Goldsworthy, S M, Foley, J F, McAllister, K A, Bennett, L M, Collins, N K, Bunch, D O, Brown, P, Wiseman, R W, Davis, B J

“…The mouse homologues of the breast cancer susceptibility genes, Brca1 and Brca2, are expressed in a cell cycle-dependent fashion in vitro and appear to be…”
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Gut Microbial Variation and Disease Status in IgA Nephropathy: FR-PO677 by Saha, Manish K., Collie, Mary M., Derebail, Vimal K., Mottl, Amy K., Roach, Jeffrey, Bunch, Donna O., Hogan, Susan L., Andermann, Tessa, Falk, Ronald

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Measuring circulating complement activation products in myeloperoxidase and proteinase 3 antineutrophil cytoplasmic antibody vasculitis by Wu, Eveline Y., McInnis, Elizabeth A., Boyer-Suavet, Sonia, Mendoza, Carmen E., Aybar, Lydia T., Kennedy, Kristin B., Poulton, Caroline J., Henderson, Candace D., Hu, Yichun, Hogan, Susan L., Hu, Peiqi, Xiao, Hong, Nachman, Patrick H., Jennette, J. Charles, Falk, Ronald J., Bunch, Donna O.

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Hemodialysis-Related Complement and Contact Pathway Activation and Cardiovascular Risk: A Narrative Review by Skinner, Sarah C., Derebail, Vimal K., Poulton, Caroline J., Bunch, Donna O., Roy-Chaudhury, Prabir, Key, Nigel S.

“…Individuals receiving long-term hemodialysis are at increased risk of developing cardiovascular disease (CVD). Traditional cardiovascular risk factors do not…”
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Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility by Eddy, E M, Washburn, T F, Bunch, D O, Goulding, E H, Gladen, B C, Lubahn, D B, Korach, K S

“…The reproductive system of male mice homozygous for a mutation in the estrogen receptor (ER) gene (ER knock-out; ERKO) appears normal at the anatomical level…”
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Glyceraldehyde 3-phosphate dehydrogenase-S protein distribution during mouse spermatogenesis by BUNCH, D. O, WELCH, J. E, MAGYAR, P. L, EDDY, E. M, O'BRIEN, D. A

“…The spermatogenic cell-specific isoform of glyceraldehyde 3-phosphate dehydrogenase (GAPD-S) may regulate glycolysis and energy production required for sperm…”
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Brca2-Null Embryonic Survival is Prolonged on the BALB/c Genetic Background by Bennett, L. Michelle, McAllister, Kimberly A., Blackshear, Pamela E., Malphurs, Jason, Goulding, Gina, Collins, N. Keith, Ward, Toni, Bunch, Donna O., Eddy, Edward M., Davis, Barbara J., Wiseman, Roger W.

“…Women who inherit mutations in the BRCA2 cancer susceptibility gene have an 85% chance of developing breast cancer. The function of the BRCA2 gene remains…”
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ANCA-associated Vasculitis Patients Have Defective Treg Function Exacerbated by Presence of a Suppression-Resistant Effector Population by Free, Meghan E, Bunch, Donna O, McGregor, JulieAnne, Jones, Britta E, Berg, Elisabeth A, Hogan, Susan L, Hu, Yichun, Preston, Gloria A, Jennette, J. Charles, Falk, Ronald J, Su, Maureen A

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