Search Results - "Buma, P"

Increased risk for knee replacement surgery after arthroscopic surgery for degenerative meniscal tears: a multi-center longitudinal observational study using data from the osteoarthritis initiative by Rongen, Jan J, Rovers, Maroeska M, van Tienen, Tony G, Buma, Pieter, Hannink, Gerjon

“…Summary Objective The primary objective was to assess whether patients with knee osteoarthritis and whom undergo arthroscopic meniscectomy have an increased…”
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Short Term Evaluation of an Anatomically Shaped Polycarbonate Urethane Total Meniscus Replacement in a Goat Model by Vrancken, A C T, Madej, W, Hannink, G, Verdonschot, N, van Tienen, T G, Buma, P

“…Since the treatment options for symptomatic total meniscectomy patients are still limited, an anatomically shaped, polycarbonate urethane (PCU), total meniscus…”
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Tissue adhesives for meniscus tear repair: an overview of current advances and prospects for future clinical solutions by Bochyńska, A. I., Hannink, G., Grijpma, D. W., Buma, P.

“…Menisci are crucial structures in the knee joint as they play important functions in load transfer, maintaining joint stability and in homeostasis of articular…”
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Physiological and excessive mechanical compression of articular cartilage activates Smad2/3P signaling by Madej, W, van Caam, A, Blaney Davidson, E.N, van der Kraan, P.M, Buma, P

“…Summary Objective Transforming growth factor beta (TGF-β) in articular cartilage can signal via two routes, the ALK5/Smad2/3P and the ALK1/Smad1/5/8P route,…”
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Bone ingrowth potential of electron beam and selective laser melting produced trabecular-like implant surfaces with and without a biomimetic coating by Biemond, J. E., Hannink, G., Verdonschot, N., Buma, P.

“…The bone ingrowth potential of trabecular-like implant surfaces produced by either selective laser melting (SLM) or electron beam melting (EBM), with or…”
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The sensitivity of cartilage contact pressures in the knee joint to the size and shape of an anatomically shaped meniscal implant by Khoshgoftar, M, Vrancken, A.C.T, van Tienen, T.G, Buma, P, Janssen, D, Verdonschot, N

“…Abstract Since meniscal geometry affects the cartilage contact pressures, it is essential to carefully define the geometry of the synthetic meniscal implant…”
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Functional biomechanical performance of a novel anatomically shaped polycarbonate urethane total meniscus replacement by Vrancken, A. C. T., Eggermont, F., van Tienen, T. G., Hannink, G., Buma, P., Janssen, D., Verdonschot, N.

“…Purpose To evaluate the functional biomechanical performance of a novel anatomically shaped, polycarbonate urethane total meniscus implant. Methods Five human…”
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Ageing is associated with reduction of mechanically-induced activation of Smad2/3P signaling in articular cartilage by Madej, W, van Caam, A, Blaney Davidson, E.N, Hannink, G, Buma, P, van der Kraan, P.M

“…Summary Objective Mechanical signals control key cellular processes in articular cartilage. Previously we have shown that mechanical compression is an…”
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Arthroscopic meniscectomy for degenerative meniscal tears reduces knee pain but is not cost-effective in a routine health care setting: a multi-center longitudinal observational study using data from the osteoarthritis initiative by Rongen, J.J., Govers, T.M., Buma, P., Rovers, M.M., Hannink, G.

“…It is disputed whether arthroscopic meniscectomy is an (cost-) effective treatment for degenerative meniscus tears in day-to-day clinical practice. The…”
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Unloading results in rapid loss of TGFβ signaling in articular cartilage: role of loading-induced TGFβ signaling in maintenance of articular chondrocyte phenotype? by Madej, W, van Caam, A, Davidson, E.B, Buma, P, van der Kraan, P.M

“…Summary Objective Recently it was shown that loading of articular cartilage explants activates TGFβ signaling. Here we investigated if in vivo chondrocytes…”
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Development of biodegradable hyper-branched tissue adhesives for the repair of meniscus tears by Bochyńska, A.I., Van Tienen, T.G., Hannink, G., Buma, P., Grijpma, D.W.

“…[Display omitted] Meniscus tears are one of the most commonly occurring injuries of the knee joint. Current meniscus repair techniques are challenging and do…”
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Interaction of chondrocytes, extracellular matrix and growth factors: relevance for articular cartilage tissue engineering by van der Kraan, P.M., Buma, P., van Kuppevelt, T., van Den Berg, W.B.

“…The abundant extracellular matrix of articular cartilage has to be maintained by a limited number of chondrocytes. Vice versa, the extracellular matrix has an…”
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Evaluation of novel biodegradable three‐armed‐ and hyper‐branched tissue adhesives in a meniscus explant model by Bochyńska, A. I., Hannink, G., Verhoeven, R., Grijpma, D. W., Buma, P.

“…Current treatment methods to repair meniscal tears do not bring fully satisfactory results. Tissue adhesives are considered promising alternatives, since they…”
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Adhesion of tissue glues to different biological substrates by Bochyńska, A.I., Hannink, G., Buma, P., Grijpma, D.W.

“…Tissue adhesives are attractive materials with potential to replace the use of sutures and staples in the repair of the injured tissues. The research field of…”
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3D geometry analysis of the medial meniscus – a statistical shape modeling approach by Vrancken, A. C. T., Crijns, S. P. M., Ploegmakers, M. J. M., O'Kane, C., Tienen, T. G., Janssen, D., Buma, P., Verdonschot, N.

“…The geometry‐dependent functioning of the meniscus indicates that detailed knowledge on 3D meniscus geometry and its inter‐subject variation is essential to…”
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Tissue engineering of the meniscus by Buma, P., Ramrattan, N.N., van Tienen, T.G., Veth, R.P.H.

“…Meniscus lesions are among the most frequent injuries in orthopaedic practice and they will inevitably lead to degeneration of the knee articular cartilage…”
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Articular cartilage remains healthy by loading-mediated self perpetuatinG TGF-β signaling by Madej, W, van Caam, A, Blaney Davidson, E, Buma, P, van der Kraan, P

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BMP-7 stimulates early diaphyseal fracture healing in estrogen deficient rats by Blokhuis, TJ, Buma, P, Verdonschot, N, Gotthardt, M, Hendriks, T

“…Estrogen deficiency causes postmenopausal osteoporosis. The relationship between estrogen deficiency and the high failure rate after osteoporotic fracture…”
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Polyurethane scaffold formation via a combination of salt leaching and thermally induced phase separation by Heijkants, R. G. J. C., van Calck, R. V., van Tienen, T. G., de Groot, J. H., Pennings, A. J., Buma, P., Veth, R. P. H., Schouten, A. J.

“…Porous scaffolds have been made from twopolyurethanes based on thermally induced phase separation of polymer dissolved in a DMSO/water mixture in combination…”
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Design, synthesis and properties of a degradable polyurethane scaffold for meniscus regeneration by Heijkants, R G J C, van Calck, R V, De Groot, J H, Pennings, A J, Schouten, A J, van Tienen, T G, Ramrattan, N, Buma, P, Veth, R P H

“…Longitudinal lesions in menisci are among the most frequent orthopedic problems of the knee. Repair by simple techniques is only limited to the vascular part…”
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