Search Results - "Bulos, Maya L"
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Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2
Published in eLife (21-12-2023)“…Yes-associated protein (YAP), the downstream effector of the evolutionarily conserved Hippo pathway, promotes cellular proliferation and coordinates certain…”
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Journal Article -
2
Single Ion Pair Is Essential for Stabilizing SHP2’s Open Conformation
Published in Biochemistry (Easton) (06-02-2024)“…Src-homology-2-domain-containing PTP-2 (SHP2) is a widely expressed signaling enzyme whose misregulation is associated with multiple human pathologies. SHP2’s…”
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3
S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling
Published in Proceedings of the National Academy of Sciences - PNAS (16-05-2023)“…KEAP1 (Kelch-like ECH-associated protein), a cytoplasmic repressor of the oxidative stress responsive transcription factor Nuclear factor erythroid 2-related…”
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4
Pharmacological YAP activation promotes regenerative repair of cutaneous wounds
Published in Proceedings of the National Academy of Sciences - PNAS (11-07-2023)“…Chronic cutaneous wounds remain a persistent unmet medical need that decreases life expectancy and quality of life. Here, we report that topical application of…”
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5
Acoustic trapping in the undergraduate laboratory
Published in American journal of physics (01-01-2024)“…Acoustic trapping is used in modern biophysics laboratories to study cell adhesion or aggregation, to sort particles, or to build model tissues. Here, we…”
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Journal Article -
6
Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2
Published in eLife (21-12-2023)“…Yes-associated protein (YAP), the downstream effector of the evolutionarily conserved Hippo pathway, promotes cellular proliferation and coordinates certain…”
Get full text
Journal Article