Search Results - "Bullrich, F"
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In vitro Activation of CPP32 and Mch3 by Mch4, a Novel Human Apoptotic Cysteine Protease Containing Two FADD-Like Domains
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-1996)“…Emerging evidence suggests that an amplifiable protease cascade consisting of multiple aspartatespecific cysteine proteases (ASCPs) is responsible for the…”
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2
Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice
Published in Molecular and Cellular Biology (01-10-1995)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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3
Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization
Published in Genes & development (15-07-1996)“…Plectin is a widely expressed high molecular weight protein that is involved in cytoskeleton-membrane attachment in epithelial cells, muscle, and other…”
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4
Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax
Published in Oncogene (31-07-1997)“…The ALL-1 gene is involved in human acute leukemia through chromosome translocations or internal rearrangements. ALL-1 is the human homologue of Drosophila…”
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5
Human MicroRNA Genes Are Frequently Located at Fragile Sites and Genomic Regions Involved in Cancers
Published in Proceedings of the National Academy of Sciences - PNAS (02-03-2004)“…A large number of tiny noncoding RNAs have been cloned and named microRNAs (miRs). Recently, we have reported that miR-15a and miR-16a, located at 13q14, are…”
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6
Chromosome aberrations in atypical chronic lymphocytic leukemia : a cytogenetic and interphase cytogenetic study
Published in Leukemia (01-11-1997)“…To define better the chromosomal profile of atypical chronic lymphocytic leukemia (aCLL), cytogenetic and interphase cytogenetic studies were performed in 43…”
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Frequent Deletions and Down-Regulation of Micro-RNA Genes miR15 and miR16 at 13q14 in Chronic Lymphocytic Leukemia
Published in Proceedings of the National Academy of Sciences - PNAS (26-11-2002)“…Micro-RNAs (miR genes) are a large family of highly conserved noncoding genes thought to be involved in temporal and tissue-specific gene regulation. MiRs are…”
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8
An Oligonucleotide Microchip for Genome-Wide MicroRNA Profiling in Human and Mouse Tissues
Published in Proceedings of the National Academy of Sciences - PNAS (29-06-2004)“…MicroRNAs (miRNAs) are a class of small noncoding RNA genes recently found to be abnormally expressed in several types of cancer. Here, we describe a recently…”
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9
MicroRNA Profiling Reveals Distinct Signatures in B Cell Chronic Lymphocytic Leukemias
Published in Proceedings of the National Academy of Sciences - PNAS (10-08-2004)“…Little is known about the expression levels or function of micro-RNAs (miRNAs) in normal and neoplastic cells, although it is becoming clear that miRNAs play…”
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10
Chromosomal mapping of cell death proteases CPP32, MCH2, and MCH3
Published in Genomics (San Diego, Calif.) (01-09-1996)“…Apoptosis may involve a specialized proteolytic cascade catalyzed by interleukin-1beta-converting enzyme-like proteases. We have recently identified three new…”
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11
Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia : Correlations with In vitro and In vivo chemoresponses
Published in Blood (01-05-1998)“…B-cell chronic lymphocytic leukemia (B-CLL) represents a neoplastic disorder caused primarily by defective programmed cell death (PCD), as opposed to increased…”
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12
Familial Cancer Associated with a Polymorphism in ARLTS1
Published in The New England journal of medicine (21-04-2005)“…ARLTS1 is a member of a large family of genes that encode proteins with a variety of functions, such as membrane and vesicular transport. These investigators…”
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13
Akt Phosphorylates and Regulates the Orphan Nuclear Receptor Nur77
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2001)“…The immediate early gene NUR77 (also called NGFI-B) is required for T cell antigen receptor-mediated cell death and is induced to very high levels in immature…”
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Chromosomal mapping of the genes GPRK5 and GPRK6 encoding G protein-coupled receptor kinases GRK5 and GRK6
Published in Cytogenetics and cell genetics (01-01-1995)“…G protein-coupled receptor kinases (GRKs) play an important role in phosphorylating and regulating the activity of a variety of G protein-coupled receptors…”
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15
ATM mutations in B-cell chronic lymphocytic leukemia
Published in Cancer research (Chicago, Ill.) (1999)“…Mutations in the ATM gene located on the long arm of chromosome 11 at 11q22-23 cause ataxia-telangiectasia, an autosomal recessive disorder that is associated…”
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Emergence of Flat Cells from Glia in Stationary Cultures of Embryonic Chick Neural Retina
Published in In Vitro Cellular & Developmental Biology (01-11-1990)“…When embryonic retina is dissociated into a single cell suspension and maintained in stationary culture, a population of flat cells is found on the culture…”
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Characterization of the 13q14 tumor suppressor locus in CLL : Identification of ALT1, an alternative splice variant of the LEU2 gene
Published in Cancer research (Chicago, Ill.) (15-09-2001)“…Chromosome 13q14 deletions constitute the most common genetic abnormality in chronic lymphocytic leukemia (CLL). To identify the putative tumor suppressor gene…”
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18
FLAME-1, a Novel FADD-like Anti-apoptotic Molecule That Regulates Fas/TNFR1-induced Apoptosis
Published in The Journal of biological chemistry (25-07-1997)“…We identified and cloned a novel human protein that contains FADD/Mort1 death effector domain homology regions, designated FLAME-1. FLAME-1, although most…”
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A novel zinc finger gene is fused to EWS in small round cell tumor
Published in Oncogene (03-08-2000)“…Ewing sarcoma family of tumors share recurrent translocations that fuse EWS from 22q12 to five different members of transcription factors namely FLI-1, ERG,…”
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Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia
Published in Cancer research (Chicago, Ill.) (01-04-2001)“…Chromosome 13q14 deletions constitute the most common structural aberration in B-cell chronic lymphocytic leukemia (B-CLL). We constructed a high-resolution…”
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