Search Results - "Bullock, Marc D."
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Exosomal microRNAs derived from colorectal cancer-associated fibroblasts: role in driving cancer progression
Published in Aging (Albany, NY.) (28-12-2017)“…Colorectal cancer is a global disease with increasing incidence. Mortality is largely attributed to metastatic spread and therefore, a mechanistic dissection…”
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Long Non-Coding RNAs in Endometrial Carcinoma
Published in International Journal of Molecular Sciences (04-11-2015)“…Endometrial carcinoma (EC), the second most common form of gynaecological malignancy, can be divided into two distinct sub-types: Type I tumours arise from…”
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MicroRNAs: critical regulators of epithelial to mesenchymal (EMT) and mesenchymal to epithelial transition (MET) in cancer progression
Published in Biology of the cell (01-01-2012)“…MicroRNAs (miRNAs) are a class of small highly conserved RNAs that provide widespread expressional control through the translational repression of mRNA. MiRNAs…”
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MicroRNAs in Testicular Cancer Diagnosis and Prognosis
Published in Urologic clinics of North America (01-02-2016)“…Testicular cancer processes a unique and clear miRNA expression signature. This differentiates testicular cancer from most other cancer types, which are…”
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The significance of pretreatment anemia in the era of R-IPI and NCCN-IPI prognostic risk assessment tools: a dual-center study in diffuse large B-cell lymphoma patients
Published in European journal of haematology (01-12-2015)“…Background Anemia is frequently identified at the time of diagnosis in patients with diffuse large B‐cell lymphoma (DLBCL); however, studies addressing the…”
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Stratifying risk of recurrence in stage II colorectal cancer using deregulated stromal and epithelial microRNAs
Published in Oncotarget (30-03-2015)“…MicroRNAs (miRNAs) enable colonic epithelial cells to acquire malignant characteristics and metastatic capabilities. Recently, cancer relevant miRNAs…”
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A top-down view of the tumor microenvironment: structure, cells and signaling
Published in Frontiers in cell and developmental biology (29-05-2015)“…It is well established that the tumor microenvironment (TME) contributes to cancer progression. Stromal cells can be divided into mesenchymal, vascular, and…”
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Exosomal microRNAs (exomiRs): Small molecules with a big role in cancer
Published in Cancer letters (28-04-2018)“…Exosomes are secreted vesicles which can transmit molecular cargo between cells. Exosomal microRNAs (exomiRs) have drawn much attention in recent years because…”
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Molecular Targeted Therapies in Hepatocellular Carcinoma: Past, Present and Future
Published in Anticancer research (01-11-2015)“…Hepatocellular carcinoma (HCC) is an aggressive tumor and the sixth most common form of cancer worldwide. Surgery is the gold-standard treatment for local…”
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miR-153 Supports Colorectal Cancer Progression via Pleiotropic Effects That Enhance Invasion and Chemotherapeutic Resistance
Published in Cancer research (Chicago, Ill.) (01-11-2013)“…Although microRNAs (miRNA) have been broadly studied in cancer, comparatively less is understood about their role in progression. Here we report that miR-153…”
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The clinical and biological significance of MIR-224 expression in colorectal cancer metastasis
Published in Gut (01-06-2016)“…MicroRNA (miRNA) expression profile can be used as prognostic marker for human cancers. We aim to explore the significance of miRNAs in colorectal cancer (CRC)…”
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The clinical significance of fibrinogen plasma levels in patients with diffuse large B cell lymphoma
Published in Journal of clinical pathology (01-04-2016)“…Fibrinogen plays a crucial role in the pathophysiology of tumour cell growth, invasion and metastasis. The aim of this study was to evaluate the prognostic…”
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Exosomal Non-Coding RNAs: Diagnostic, Prognostic and Therapeutic Applications in Cancer
Published in Non-coding RNA (03-06-2015)“…Non-coding RNAs, such as microRNAs and long non-coding RNAs, are important regulatory molecules which are corrupted in cancer, often in a tissue and stage…”
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Estrogen and breast cancer: can less mean more?
Published in Cell cycle (Georgetown, Tex.) (18-07-2015)Get full text
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Molecular profiling of the invasive tumor microenvironment in a 3-dimensional model of colorectal cancer cells and ex vivo fibroblasts
Published in Journal of visualized experiments (29-04-2014)“…Invading colorectal cancer (CRC) cells have acquired the capacity to break free from their sister cells, infiltrate the stroma, and remodel the extracellular…”
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Abstract 3075: Dysregulated stromal microRNAs promote metastatic progression in colorectal cancer
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Background MicroRNAs, which are key drivers of colorectal cancer (CRC) tumorogenesis, are also increasingly implicated in metastatic progression. Equally…”
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