Search Results - "Bullmore, Edward"
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1
Small-World Brain Networks Revisited
Published in The Neuroscientist (01-10-2017)“…It is nearly 20 years since the concept of a small-world network was first quantitatively defined, by a combination of high clustering and short path length;…”
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Cortical Thickness and Connectivity in Schizophrenia
Published in The American journal of psychiatry (01-07-2019)“…It is salutary to recall that schizophrenia was generally regarded as a functional psychosis, rather than an organic psychosis like dementia, at that time,…”
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3
Network-based statistic: Identifying differences in brain networks
Published in NeuroImage (Orlando, Fla.) (01-12-2010)“…Large-scale functional or structural brain connectivity can be modeled as a network, or graph. This paper presents a statistical approach to identify…”
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Connectomics: A new paradigm for understanding brain disease
Published in European neuropsychopharmacology (01-05-2015)“…Abstract In recent years, pathophysiological models of brain disorders have shifted from an emphasis on understanding pathology in specific brain regions to…”
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5
Reconciling abnormalities of brain network structure and function in schizophrenia
Published in Current opinion in neurobiology (01-02-2015)“…Highlights • Schizophrenia patients often show reduced structural connectivity. • Despite this, increased functional connectivity is a common finding. •…”
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Microstructural and functional gradients are increasingly dissociated in transmodal cortices
Published in PLoS biology (20-05-2019)“…While the role of cortical microstructure in organising neural function is well established, it remains unclear how structural constraints can give rise to…”
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7
Immune targets for therapeutic development in depression: towards precision medicine
Published in Nature reviews. Drug discovery (01-03-2022)“…Over the past two decades, compelling evidence has emerged indicating that immune mechanisms can contribute to the pathogenesis of major depressive disorder…”
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Schizophrenia, neuroimaging and connectomics
Published in NeuroImage (Orlando, Fla.) (01-10-2012)“…Schizophrenia is frequently characterized as a disorder of brain connectivity. Neuroimaging has played a central role in supporting this view, with nearly two…”
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Brain graphs: graphical models of the human brain connectome
Published in Annual review of clinical psychology (27-04-2011)“…Brain graphs provide a relatively simple and increasingly popular way of modeling the human brain connectome, using graph theory to abstractly define a nervous…”
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10
Micro-connectomics: probing the organization of neuronal networks at the cellular scale
Published in Nature reviews. Neuroscience (01-03-2017)“…Key Points Micro-connectomics provides a promising approach to studying the wiring rules of neuronal network organization at the cellular scale and eventually…”
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11
The Multilayer Connectome of Caenorhabditis elegans
Published in PLoS computational biology (01-12-2016)“…Connectomics has focused primarily on the mapping of synaptic links in the brain; yet it is well established that extrasynaptic volume transmission, especially…”
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12
Modular and hierarchically modular organization of brain networks
Published in Frontiers in neuroscience (01-01-2010)“…Brain networks are increasingly understood as one of a large class of information processing systems that share important organizational principles in common,…”
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The hubs of the human connectome are generally implicated in the anatomy of brain disorders
Published in Brain (London, England : 1878) (01-08-2014)“…Brain networks or 'connectomes' include a minority of highly connected hub nodes that are functionally valuable, because their topological centrality supports…”
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14
Making Connections: Biological Mechanisms of Human Brain (Dys)connectivity
Published in Biological psychiatry (1969) (01-03-2023)Get full text
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Comparative Connectomics
Published in Trends in cognitive sciences (01-05-2016)“…We introduce comparative connectomics, the quantitative study of cross-species commonalities and variations in brain network topology that aims to discover…”
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Annual Research Review: Growth connectomics - the organization and reorganization of brain networks during normal and abnormal development
Published in Journal of child psychology and psychiatry (01-03-2015)“…Background We first give a brief introduction to graph theoretical analysis and its application to the study of brain network topology or connectomics. Within…”
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Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in autism
Published in Molecular psychiatry (01-07-2019)“…Differences in cortical morphology—in particular, cortical volume, thickness and surface area—have been reported in individuals with autism. However, it is…”
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Wiring cost and topological participation of the mouse brain connectome
Published in Proceedings of the National Academy of Sciences - PNAS (11-08-2015)“…Brain connectomes are topologically complex systems, anatomically embedded in 3D space. Anatomical conservation of “wiring cost” explains many but not all…”
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Endogenous human brain dynamics recover slowly following cognitive effort
Published in PloS one (14-08-2009)“…In functional magnetic resonance imaging, the brain's response to experimental manipulation is almost always assumed to be independent of endogenous…”
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Conservative and disruptive modes of adolescent change in human brain functional connectivity
Published in Proceedings of the National Academy of Sciences - PNAS (11-02-2020)“…Adolescent changes in human brain function are not entirely understood. Here, we used multiecho functional MRI (fMRI) to measure developmental change in…”
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