Search Results - "Bullido, Maria"

Oxidative stress enhances neurodegeneration markers induced by herpes simplex virus type 1 infection in human neuroblastoma cells by Santana, Soraya, Sastre, Isabel, Recuero, Maria, Bullido, Maria J, Aldudo, Jesus

“…Mounting evidence suggests that Herpes simplex virus type 1 (HSV-1) is involved in the pathogenesis of Alzheimer's disease (AD). Previous work from our…”
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Herpes simplex virus type 2 infection induces AD-like neurodegeneration markers in human neuroblastoma cells by Kristen, Henrike, Santana, Soraya, Sastre, Isabel, Recuero, Maria, Bullido, Maria J, Aldudo, Jesus

“…Abstract Herpes simplex virus (HSV) types 1 and 2 are neurotropic viruses that establish lifelong latent infections in neurons. Mounting evidence suggests that…”
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Metabolic Overlap between Alzheimer's Disease and Metabolic Syndrome Identifies the PVRL2 Gene as a New Modulator of Diabetic Dyslipidemia by Guardiola, Montse, Muntané, Gerard, Martínez, Iris, Martorell, Lourdes, Girona, Josefa, Ibarretxe, Daiana, Plana, Núria, Bullido, María J, Vilella, Elisabet, Ribalta, Josep

“…Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) share metabolic alterations such as abnormal insulin and lipid metabolism and have some common…”
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Herpes simplex virus type I induces the accumulation of intracellular β-amyloid in autophagic compartments and the inhibition of the non-amyloidogenic pathway in human neuroblastoma cells by Santana, Soraya, Recuero, Maria, Bullido, Maria Jesús, Valdivieso, Fernando, Aldudo, Jesus

“…Abstract Mounting evidence suggests that herpes simplex virus type 1 (HSV-1) is involved in the pathogenesis of Alzheimer's disease (AD). Epidemiological…”
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Microbes and Alzheimer's Disease by Itzhaki, Ruth F, Lathe, Richard, Balin, Brian J, Ball, Melvyn J, Bearer, Elaine L, Braak, Heiko, Bullido, Maria J, Carter, Chris, Clerici, Mario, Cosby, S Louise, Del Tredici, Kelly, Field, Hugh, Fulop, Tamas, Grassi, Claudio, Griffin, W Sue T, Haas, Jürgen, Hudson, Alan P, Kamer, Angela R, Kell, Douglas B, Licastro, Federico, Letenneur, Luc, Lövheim, Hugo, Mancuso, Roberta, Miklossy, Judith, Otth, Carola, Palamara, Anna Teresa, Perry, George, Preston, Christopher, Pretorius, Etheresia, Strandberg, Timo, Tabet, Naji, Taylor-Robinson, Simon D, Whittum-Hudson, Judith A

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Human in vivo evidence of associations between herpes simplex virus and cerebral amyloid-beta load in normal aging by Cantero, Jose L, Atienza, Mercedes, Sastre, Isabel, Bullido, María Jesús

“…Mounting data suggests that herpes simplex virus type 1 (HSV-1) is involved in the pathogenesis of AD, possibly instigating amyloid-beta (Aβ) accumulation…”
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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease by Jaillard, Céline, Bettens, Karolien, Alpérovitch, Annick, Van Broeckhoven, Christine, Ritchie, Karen, Mancuso, Michelangelo, Fiévet, Nathalie, Annoni, Giorgio, Galimberti, Daniela, Alvarez, Victoria, Tzourio, Christophe, Gut, Ivo, Leveillard, Thierry, Licastro, Federico, Zelenika, Diana, Panza, Francesco, Soininen, Hilkka, Barberger-Gateau, Pascale, Pasquier, Florence, Lendon, Corinne, De Deyn, Peter, Bullido, Maria J, Hiltunen, Mikko, Dufouil, Carole, Piccardi, Paola, Lambert, Jean-Charles, Seripa, Davide, Blanché, Hélène, Dartigues, Jean-François, Nacmias, Benedetta, de Pancorbo, Marian M, Lathrop, Mark, Hannequin, Didier, Franck, Ana, Heath, Simon, Hanon, Olivier, Tavernier, Béatrice, Bosco, Paolo, Porcellini, Elisa, Letenneur, Luc, Engelborghs, Sebastiaan, Even, Gael, Berr, Claudine, Amouyel, Philippe, Campion, Dominique, Mateo, Ignacio, Combarros, Onofre, Helisalmi, Seppo, Sleegers, Kristel, Bossù, Paola

“…The gene encoding apolipoprotein E (APOE) on chromosome 19 is the only confirmed susceptibility locus for late-onset Alzheimer's disease. To identify other…”
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Choroid plexus implants rescue Alzheimer’s disease-like pathologies by modulating amyloid-β degradation by Bolos, Marta, Antequera, Desireé, Aldudo, Jesús, Kristen, Henrike, Bullido, María Jesús, Carro, Eva

“…The choroid plexuses (CP) release numerous biologically active enzymes and neurotrophic factors, and contain a subpopulation of neural progenitor cells…”
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Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease by Le Guen, Yann, Belloy, Michael E, Grenier-Boley, Benjamin, de Rojas, Itziar, Castillo-Morales, Atahualpa, Jansen, Iris, Nicolas, Aude, Bellenguez, Céline, Dalmasso, Carolina, Küçükali, Fahri, Eger, Sarah J, Rasmussen, Katrine Laura, Thomassen, Jesper Qvist, Deleuze, Jean-François, He, Zihuai, Napolioni, Valerio, Amouyel, Philippe, Jessen, Frank, Kehoe, Patrick G, van Duijn, Cornelia, Tsolaki, Magda, Sánchez-Juan, Pascual, Sleegers, Kristel, Ingelsson, Martin, Rossi, Giacomina, Hiltunen, Mikko, Sims, Rebecca, van der Flier, Wiesje M, Ramirez, Alfredo, Andreassen, Ole A, Frikke-Schmidt, Ruth, Williams, Julie, Ruiz, Agustín, Lambert, Jean-Charles, Greicius, Michael D, Arosio, Beatrice, Benussi, Luisa, Boland, Anne, Borroni, Barbara, Caffarra, Paolo, Daian, Delphine, Daniele, Antonio, Debette, Stéphanie, Dufouil, Carole, Düzel, Emrah, Galimberti, Daniela, Giedraitis, Vilmantas, Grimmer, Timo, Graff, Caroline, Grünblatt, Edna, Hanon, Olivier, Hausner, Lucrezia, Heilmann-Heimbach, Stefanie, Holstege, Henne, Hort, Jakub, Jürgen, Deckert, Kuulasmaa, Teemu, van der Lugt, Aad, Masullo, Carlo, Mecocci, Patrizia, Mehrabian, Shima, de Mendonça, Alexandre, Moebus, Susanne, Nacmias, Benedetta, Nicolas, Gael, Olaso, Robert, Papenberg, Goran, Parnetti, Lucilla, Pasquier, Florence, Peters, Oliver, Pijnenburg, Yolande A L, Popp, Julius, Rainero, Innocenzo, Ramakers, Inez, Riedel-Heller, Steffi, Scarmeas, Nikolaos, Scheltens, Philip, Scherbaum, Norbert, Schneider, Anja, Seripa, Davide, Soininen, Hilkka, Solfrizzi, Vincenzo, Spalletta, Gianfranco, Squassina, Alessio, van Swieten, John, Tegos, Thomas J, Tremolizzo, Lucio, Verhey, Frans, Vyhnalek, Martin, Wiltfang, Jens, Boada, Mercè, García-González, Pablo, Puerta, Raquel, Real, Luis M, Álvarez, Victoria, Bullido, María J, Clarimon, Jordi, García-Alberca, José María, Mir, Pablo, Moreno, Fermin

“…The APOE ε2 and APOE ε4 alleles are the strongest protective and risk-increasing, respectively, genetic variants for late-onset Alzheimer disease (AD)…”
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Assessing the role of the TREM2 p.R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia by Ruiz, Agustín, Dols-Icardo, Oriol, Bullido, María J, Pastor, Pau, Rodríguez-Rodríguez, Eloy, López de Munain, Adolfo, de Pancorbo, Marian M, Pérez-Tur, Jordi, Álvarez, Victoria, Antonell, Anna, López-Arrieta, Jesús, Hernández, Isabel, Tárraga, Lluís, Boada, Mercè, Lleó, Alberto, Blesa, Rafael, Frank-García, Ana, Sastre, Isabel, Razquin, Cristina, Ortega-Cubero, Sara, Lorenzo, Elena, Sánchez-Juan, Pascual, Combarros, Onofre, Moreno, Fermín, Gorostidi, Ana, Elcoroaristizabal, Xabier, Baquero, Miquel, Coto, Eliecer, Sánchez-Valle, Raquel, Clarimón, Jordi

“…Abstract A non-synonymous genetic rare variant, rs75932628-T (p.R47H), in the TREM2 gene has recently been reported to be a strong genetic risk factor for…”
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Matrix metalloproteinase 14 regulates HSV-1 infection in neuroblastoma cells by Llorente, Patricia, Mejías, Víctor, Sastre, Isabel, Recuero, María, Aldudo, Jesús, Bullido, Maria J.

“…Growing evidence supports that chronic or latent infection of the central nervous system might be implicated in Alzheimer's disease (AD). Among them, Herpes…”
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The lysosome system is severely impaired in a cellular model of neurodegeneration induced by HSV-1 and oxidative stress by Kristen, Henrike, Sastre, Isabel, Muñoz-Galdeano, Teresa, Recuero, Maria, Aldudo, Jesus, Bullido, Maria J.

“…The causal agent(s) and molecular mechanisms of Alzheimer's disease (AD) remain unclear. Mounting evidence suggests that herpes simplex virus type 1 (HSV-1)…”
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Herpes simplex virus type I induces an incomplete autophagic response in human neuroblastoma cells by Santana, Soraya, Bullido, Maria Jesús, Recuero, Maria, Valdivieso, Fernando, Aldudo, Jesus

“…Autophagy is a homeostatic process involved in the turnover or elimination of cytoplasmic components, damaged organelles, and protein aggregates via a…”
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Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases by Calero, Olga, Bullido, María J, Clarimón, Jordi, Frank-García, Ana, Martínez-Martín, Pablo, Lleó, Alberto, Rey, María Jesús, Rábano, Alberto, Blesa, Rafael, Gómez-Isla, Teresa, Valdivieso, Fernando, de Pedro-Cuesta, Jesús, Ferrer, Isidro, Calero, Miguel

“…Alzheimer's disease (AD) and Creutzfeldt-Jakob disease (CJD) represent two distinct clinical entities belonging to a wider group, generically named as…”
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LAMP2 deficiency attenuates the neurodegeneration markers induced by HSV-1 infection by Kristen, Henrike, Sastre, Isabel, Aljama, Sara, Fuentes, Maria, Recuero, Maria, Frank-García, Ana, Martin, Angel, Sanchez-Juan, Pascual, Lage, Carmen, Bullido, Maria J., Aldudo, Jesus

“…Mounting evidence suggests a major role of infectious agents in the pathogenesis of sporadic Alzheimer's disease (AD). Among them, herpes simplex virus type 1…”
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Herpes Simplex Virus Type 1 Induces AD-like Neurodegeneration Markers in Human Progenitor and Differentiated ReNcell VM Cells by Salgado, Blanca, Sastre, Isabel, Bullido, Maria J, Aldudo, Jesus

“…An increasing body of evidence strongly suggests that infections or reactivations of herpes simplex virus type 1 (HSV-1) may be closely linked to Alzheimer's…”
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Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP by Guerreiro, Rita Joao, Baquero, Miquel, Blesa, Rafael, Boada, Mercè, Brás, Jose Miguel, Bullido, Maria J, Calado, Ana, Crook, Richard, Ferreira, Carla, Frank, Ana, Gómez-Isla, Teresa, Hernández, Isabel, Lleó, Alberto, Machado, Alvaro, Martínez-Lage, Pablo, Masdeu, José, Molina-Porcel, Laura, Molinuevo, José L, Pastor, Pau, Pérez-Tur, Jordi, Relvas, Rute, Oliveira, Catarina Resende, Ribeiro, Maria Helena, Rogaeva, Ekaterina, Sa, Alfredo, Samaranch, Lluís, Sánchez-Valle, Raquel, Santana, Isabel, Tàrraga, Lluís, Valdivieso, Fernando, Singleton, Andrew, Hardy, John, Clarimón, Jordi

“…Abstract Mutations in three genes ( PSEN1 , PSEN2 , and APP ) have been identified in patients with early-onset (<65years) Alzheimer's disease (AD). We…”
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Matrix Metalloproteinase 14 Mediates APP Proteolysis and Lysosomal Alterations Induced by Oxidative Stress in Human Neuronal Cells by Bullido, Maria J., Recuero, María, Aldudo, Jesús, Sastre, Isabel, Martins, Soraia, Llorente, Patricia, Adjaye, James

“…The alteration of amyloid precursor protein (APP) proteolysis is a hallmark of Alzheimer’s disease (AD). Recent studies have described noncanonical pathways of…”
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Tetraspanin CD81 regulates HSV-1 infection by Benayas, Beatriz, Sastre, Isabel, López-Martín, Soraya, Oo, Adrian, Kim, Baek, Bullido, Maria J., Aldudo, Jesús, Yáñez-Mó, María

“…Different members of the tetraspanin superfamily have been described to regulate different virus infectious cycles at several stages: viral entry, viral…”
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Genetic associations between modifiable risk factors and Alzheimer disease by Luo, Jiao, Thomassen, Jesper Qvist, Bellenguez, Céline, Grenier-Boley, Benjamin, de Rojas, Itziar, Castillo, Atahualpa, Parveen, Kayenat, Küçükali, Fahri, Nicolas, Aude, Peters, Oliver, Schneider, Anja, Dichgans, Martin, Rujescu, Dan, Scherbaum, Norbert, Jürgen, Deckert, Riedel-Heller, Steffi, Hausner, Lucrezia, Porcel, Laura Molina, Düzel, Emrah, Grimmer, Timo, Wiltfang, Jens, Heilmann-Heimbach, Stefanie, Moebus, Susanne, Tegos, Thomas, Scarmeas, Nikolaos, Clarimon, Jordi, Moreno, Fermin, Pérez-Tur, Jordi, Bullido, María J., Pastor, Pau, Sánchez-Valle, Raquel, Álvarez, Victoria, Boada, Mercè, García-González, Pablo, Puerta, Raquel, Mir, Pablo, Real, Luis M., Piñol-Ripoll, Gerard, García-Alberca, Jose María, Royo, Jose Luís, Rodriguez-Rodriguez, Eloy, Soininen, Hilkka, Kuulasmaa, Teemu, de Mendonça, Alexandre, Mehrabian, Shima, Hort, Jakub, Vyhnalek, Martin, van der Lee, Sven, Graff, Caroline, Papenberg, Goran, Giedraitis, Vilmantas, Boland, Anne, Bacq-Daian, Delphine, Deleuze, Jean-François, Nicolas, Gael, Dufouil, Carole, Pasquier, Florence, Hanon, Olivier, Debette, Stéphanie, Grünblatt, Edna, Popp, Julius, Benussi, Luisa, Galimberti, Daniela, Arosio, Beatrice, Mecocci, Patrizia, Solfrizzi, Vincenzo, Parnetti, Lucilla, Squassina, Alessio, Tremolizzo, Lucio, Borroni, Barbara, Nacmias, Benedetta, Sorbi, Sandro, Caffarra, Paolo, Seripa, Davide, Rainero, Innocenzo, Daniele, Antonio, Masullo, Carlo, Spalletta, Gianfranco, Williams, Julie, Amouyel, Philippe, Jessen, Frank, Kehoe, Patrick, Magda, Tsolaki, Rossi, Giacomina, Sánchez-Juan, Pascual, Sleegers, Kristel, Ingelsson, Martin, Andreassen, Ole A., Hiltunen, Mikko, Van Duijn, Cornelia, Sims, Rebecca, van der Flier, Wiesje, Ruiz, Agustín, Ramirez, Alfredo, Lambert, Jean-Charles, Frikke-Schmidt, Ruth

“…© 2023 European Alzheimer’s & Dementia Biobank Mendelian Randomization (EADB-MR) Collaboration. JAMA Network Open. Open Access: This is an open access article…”
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