Search Results - "Bull, Rowena A."
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Evolution of the SARS‐CoV‐2 omicron variants BA.1 to BA.5: Implications for immune escape and transmission
Published in Reviews in medical virology (01-09-2022)“…The first dominant SARS‐CoV‐2 Omicron variant BA.1 harbours 35 mutations in its Spike protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon…”
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Broadly-Neutralizing Antibodies Against Emerging SARS-CoV-2 Variants
Published in Frontiers in immunology (27-09-2021)“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have become a major concern in the containment of current pandemic. The…”
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Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis
Published in Nature communications (09-12-2020)“…Viral whole-genome sequencing (WGS) provides critical insight into the transmission and evolution of Severe Acute Respiratory Syndrome Coronavirus 2…”
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Rapid evolution of pandemic noroviruses of the GII.4 lineage
Published in PLoS pathogens (01-03-2010)“…Over the last fifteen years there have been five pandemics of norovirus (NoV) associated gastroenteritis, and the period of stasis between each pandemic has…”
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The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry
Published in The Journal of biological chemistry (23-10-2015)“…The interferon-induced transmembrane (IFITM) family of proteins have recently been identified as important host effector molecules of the type I interferon…”
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Norovirus recombination
Published in Journal of general virology (01-12-2007)“…School of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney 2052, Australia Correspondence Peter A. White…”
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Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease
Published in Nature communications (26-02-2018)“…Severe influenza A virus (IAV) infection is associated with immune dysfunction. Here, we show circulating CD8 + T-cell profiles from patients hospitalized with…”
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Respiratory viral co-infections among SARS-CoV-2 cases confirmed by virome capture sequencing
Published in Scientific reports (16-02-2021)“…Accumulating evidence supports the high prevalence of co-infections among Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) patients, and their…”
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Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection
Published in PLoS pathogens (01-09-2011)“…Hepatitis C is a pandemic human RNA virus, which commonly causes chronic infection and liver disease. The characterization of viral populations that…”
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Viral quasispecies assembly via maximal clique enumeration
Published in PLoS computational biology (01-03-2014)“…Virus populations can display high genetic diversity within individual hosts. The intra-host collection of viral haplotypes, called viral quasispecies, is an…”
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Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
Published in Nature communications (08-02-2023)“…Emerging variants of concern (VOCs) are threatening to limit the effectiveness of SARS-CoV-2 monoclonal antibodies and vaccines currently used in clinical…”
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Maintenance of broad neutralizing antibodies and memory B cells 1 year post-infection is predicted by SARS-CoV-2-specific CD4+ T cell responses
Published in Cell reports (Cambridge) (08-02-2022)“…Understanding the long-term maintenance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity is critical for predicting protection against…”
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Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design
Published in PLoS pathogens (17-05-2019)“…Cumulative evidence supports a role for neutralizing antibodies contributing to spontaneous viral clearance during acute hepatitis C virus (HCV) infection…”
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Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance
Published in Viruses (29-09-2015)“…The hepatitis C virus (HCV) is a pandemic human pathogen posing a substantial health and economic burden in both developing and developed countries…”
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Contribution of Intra- and Interhost Dynamics to Norovirus Evolution
Published in Journal of Virology (01-03-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Genome-Wide Mutagenesis of Dengue Virus Reveals Plasticity of the NS1 Protein and Enables Generation of Infectious Tagged Reporter Viruses
Published in Journal of virology (01-12-2017)“…Dengue virus (DENV) is a major global pathogen that causes significant morbidity and mortality in tropical and subtropical areas worldwide. An improved…”
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Identification of human progenitors of exhausted CD8+ T cells associated with elevated IFN-γ response in early phase of viral infection
Published in Nature communications (07-12-2022)“…T cell exhaustion is a hallmark of hepatitis C virus (HCV) infection and limits protective immunity in chronic viral infections and cancer. Limited knowledge…”
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A method for near full-length amplification and sequencing for six hepatitis C virus genotypes
Published in BMC genomics (17-03-2016)“…Hepatitis C virus (HCV) is a rapidly evolving RNA virus that has been classified into seven genotypes. All HCV genotypes cause chronic hepatitis, which…”
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Conserved epitopes with high HLA-I population coverage are targets of CD8+ T cells associated with high IFN-γ responses against all dengue virus serotypes
Published in Scientific reports (24-11-2020)“…Cytotoxic CD8 + T cells are key for immune protection against viral infections. The breadth and cross-reactivity of these responses are important against…”
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Hepatitis C Virus Epitope Immunodominance and B Cell Repertoire Diversity
Published in Viruses (25-05-2021)“…Despite the advent of effective, curative treatments for hepatitis C virus (HCV), a preventative vaccine remains essential for the global elimination of HCV…”
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