Search Results - "Bull, Rowena"
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Evolution of the SARS‐CoV‐2 omicron variants BA.1 to BA.5: Implications for immune escape and transmission
Published in Reviews in medical virology (01-09-2022)“…The first dominant SARS‐CoV‐2 Omicron variant BA.1 harbours 35 mutations in its Spike protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon…”
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Broadly-Neutralizing Antibodies Against Emerging SARS-CoV-2 Variants
Published in Frontiers in immunology (27-09-2021)“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have become a major concern in the containment of current pandemic. The…”
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Rapid evolution of pandemic noroviruses of the GII.4 lineage
Published in PLoS pathogens (01-03-2010)“…Over the last fifteen years there have been five pandemics of norovirus (NoV) associated gastroenteritis, and the period of stasis between each pandemic has…”
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Inhibitors of the Hepatitis C Virus Polymerase; Mode of Action and Resistance
Published in Viruses (29-09-2015)“…The hepatitis C virus (HCV) is a pandemic human pathogen posing a substantial health and economic burden in both developing and developed countries…”
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Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis
Published in Nature communications (09-12-2020)“…Viral whole-genome sequencing (WGS) provides critical insight into the transmission and evolution of Severe Acute Respiratory Syndrome Coronavirus 2…”
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Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection
Published in PLoS pathogens (01-09-2011)“…Hepatitis C is a pandemic human RNA virus, which commonly causes chronic infection and liver disease. The characterization of viral populations that…”
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Viral quasispecies assembly via maximal clique enumeration
Published in PLoS computational biology (01-03-2014)“…Virus populations can display high genetic diversity within individual hosts. The intra-host collection of viral haplotypes, called viral quasispecies, is an…”
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The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry
Published in The Journal of biological chemistry (23-10-2015)“…The interferon-induced transmembrane (IFITM) family of proteins have recently been identified as important host effector molecules of the type I interferon…”
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Mechanisms of GII.4 norovirus evolution
Published in Trends in microbiology (Regular ed.) (01-05-2011)“…Since the late 1990 s norovirus (NoV) strains belonging to a single genotype (GII.4) have caused at least four global epidemics. To date, the higher…”
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Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design
Published in PLoS pathogens (17-05-2019)“…Cumulative evidence supports a role for neutralizing antibodies contributing to spontaneous viral clearance during acute hepatitis C virus (HCV) infection…”
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Total recall? Understanding the effect of antigenic distance on original antigenic sin
Published in Immunology and cell biology (01-05-2023)“…Vaccination‐induced antibodies are critical for protective immunity against pathogenic threats. “Original antigenic sin” (OAS), also referred to as imprinting,…”
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Norovirus recombination
Published in Journal of general virology (01-12-2007)“…School of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney 2052, Australia Correspondence Peter A. White…”
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13
Getting to the (germinal) center of humoral immune responses to SARS-CoV-2
Published in Cell (17-03-2022)“…Long-term protection against SARS-CoV-2 requires effective and durable immunity. In this issue of Cell, two papers closely examine germinal centers, the…”
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14
Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease
Published in Nature communications (26-02-2018)“…Severe influenza A virus (IAV) infection is associated with immune dysfunction. Here, we show circulating CD8 + T-cell profiles from patients hospitalized with…”
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Optimized cell systems for the investigation of hepatitis C virus E1E2 glycoproteins
Published in Journal of general virology (01-01-2021)“…Great strides have been made in understanding and treating hepatitis C virus (HCV) thanks to the development of various experimental systems including…”
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Respiratory viral co-infections among SARS-CoV-2 cases confirmed by virome capture sequencing
Published in Scientific reports (16-02-2021)“…Accumulating evidence supports the high prevalence of co-infections among Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) patients, and their…”
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The Influence of Hepatitis C Virus Genetic Region on Phylogenetic Clustering Analysis
Published in PloS one (20-07-2015)“…Sequencing is important for understanding the molecular epidemiology and viral evolution of hepatitis C virus (HCV) infection. To date, there is little…”
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Next generation deep sequencing and vaccine design: today and tomorrow
Published in Trends in biotechnology (Regular ed.) (01-09-2012)“…Next generation sequencing (NGS) technologies have redefined the modus operandi in both human and microbial genetics research, allowing the unprecedented…”
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Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients
Published in Nature communications (08-02-2023)“…Emerging variants of concern (VOCs) are threatening to limit the effectiveness of SARS-CoV-2 monoclonal antibodies and vaccines currently used in clinical…”
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Maintenance of broad neutralizing antibodies and memory B cells 1 year post-infection is predicted by SARS-CoV-2-specific CD4+ T cell responses
Published in Cell reports (Cambridge) (08-02-2022)“…Understanding the long-term maintenance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity is critical for predicting protection against…”
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