Search Results - "Bull, Helen A."

Endothelin-1 in Human Skin: Immunolocalization, Receptor Binding, mRNA Expression, and Effects on Cutaneous Microvascular Endothelial Cells by Bull, Helen A., Bunker, Christopher B., Terenghi, Georgio, Springall, David R., Zhao, Yidan, Polak, Julia M., Dowd, Pauline M.

“…Endothelin-1 (ET-1), a potent vasoconstrictor peptide, has been implicated in the maintenance of systemic and peripheral vascular tone. We have therefore…”
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Responses of Human Dermal Microvascular Endothelial Cells to Histamine and Their Modulation by Interleukin 1 and Substance P by Bull, Helen A., Cohen, J., Dowd, Pauline M.

“…The action of histamine on human dermal microvascular endothelial cells and modulation of its effects by the cytokine interleukin-1 and the vasoactive…”
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Basophil Mediator Release in Atopic Dermatitis by Bull, Helen A., Courtney, Paul F., Bunker, Christopher B., Rustin, Malcolm H.A., Pearce, Fred L., Dowd, Pauline M.

“…Basophils have been implicated as a source of histamine and pro-inflammatory eicosanoids in atopic dermatitis. However, mechanisms regulating basophil mediator…”
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Neuropeptides Induce Release of Nitric Oxide from Human Dermal Microvascular Endothelial Cells by Bull, Helen A., Hothersall, John, Chowdhury, Nazira, Cohen, John, Dowd, Pauline M.

“…Nitric oxide is a potent mediator of endothelium-dependent vasodilatation, the synthesis of which is catalyzed by the constitutively expressed enzyme…”
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src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells by Bull, Helen A., Brickell, Paul M., Dowd, Pauline M.

“…src-related cytoplasmic PTKs are physically and functionally associated with cell surface receptors and are involved in signal transduction. In this paper we…”
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Arachidonic acid metabolites in cutaneous carcinomas by Rustin, M H, Bull, H A, Dowd, P M

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Cutaneous Responses to Endothelin-1 and Histamine in Patients with Vibration White Finger by Dowd, Pauline M., Goldsmith, Portia C., Chopra, Sunil, Bull, Helen A., Foreman, John C.

“…Vibration white finger (VWF) is the episodic blanching of the fingers that occurs in response to cold in those who work with hand-held vibrating tools…”
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Characterization of Endothelin-Binding Sites in Human Skin and their Regulation in Primary Raynaud's Phenomenon and Systemic Sclerosis by Knock, Gregory A, Terenghi, Giorgio, Bunker, Christopher B, Bull, Helen A., Dowd, Pauline M., Polak, Julia M.

“…Endothelin (ET), which mediates vasoconstrictor and vasodilator activities via multiple receptor subtypes, has been implicated in the control of blood flow and…”
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Effects of the Lupus Anticoagulant in Patients with Systemic lupus Erythematosus on Endothelial Cell Prostacyclin Release and Procoagulant Activity by Rustin, Malcolm H.A., Bull, Helen A., Machin, Samuel J., Isenberg, David A., Snaith, Michael L., Dowd, Pauline M.

“…A disturbance in endothelial cell (EC) function maybe pathogenetic in the thrombotic tendency of patients with the lupus anticoagulant (LA). The ability of…”
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Molecular Characterization of Quinine/Quinidine Drug-Dependent Antibody Platelet Interaction Using Monoclonal Antibodies by Berndt, Michael C., Chong, Beng H., Bull, Helen A., Zola, Heddy, Castaldi, Peter A.

“…Two murine monoclonal antibodies, FMC 25 and AN 51, directed against distinct epitopes on the glycoprotein lb complex, have been used to further define the…”
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Characterization of histamine receptor sub‐types regulating prostacyclin release from human endothelial cells by Bull, Helen A., Courtney, P.F., Rustin, M.H.A., Dowd, Pauline M.

“…1 The histamine receptor sub‐types that are involved in the initiation and maintenance of prostacyclin (PGI2) release from human endothelial cells have been…”
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Pro-inflammatory mediators induce sustained release of prostaglandin E2 from human dermal microvascular endothelial cells by Bull, H A, Rustin, M H, Spaull, J, Cohen, J, Wilson-Jones, E, Dowd, P M

“…The vasodilator prostaglandin E2 has been proposed as a mediator of erythema in a variety of cutaneous inflammatory reactions and prostacyclin levels have been…”
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Interleukin‐1 potentiates histamine‐induced release of prostacyclin from human endothelial cells by Bull, Helen A., Dowd, Pauline M.

“…1 In human cultured umbilical vein endothelial cells, interleukin‐1 potentiated histamine‐induced release of prostacyclin in a time‐ and…”
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Raynaud's phenomenon, calcitonin gene-related peptide, endothelin, and cutaneous vasculature by Dowd, P M, Bunker, C B, Bull, H A, Foreman, J C, Terenghi, G, Springall, D R, Polak, J M

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Effect of human recombinant interleukin-I alpha on release of prostacyclin from human endothelial cells by Rustin, M H, Bull, H A, Dowd, P M

“…Incubation of human recombinant IL-1 alpha (hrIL-1 alpha) with cultured human endothelial cells induced a dose- and time-dependent increase in the release of…”
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Release of prostacyclin from cultured human endothelial cells following prolonged exposure to histamine by Bull, H A, Rustin, M H, Dowd, P M

“…Histamine is an important pro-inflammatory molecule mediating leukocyte margination, plasma extravasation and vasodilation, but its precise mode of action on…”
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Serum From Patients With Raynaud's Phenomenon Inhibits Prostacyclin Production by Rustin, Malcolm H.A., Bull, Helen A., Machin, Samuel J., Koro, Osamu, Dowd, Pauline M.

“…Prostacyclin (PGI2) and PGE2, the predominant cyclooxygenase products of endothelial cells are potent vasodilators. An inability to produce appropriate…”
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The haemostatic function of the vascular endothelial cell by Bull, H A, Machin, S J

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