Search Results - "Bull, A."

Evolution of the SARS‐CoV‐2 omicron variants BA.1 to BA.5: Implications for immune escape and transmission by Shrestha, Lok Bahadur, Foster, Charles, Rawlinson, William, Tedla, Nicodemus, Bull, Rowena A.

“…The first dominant SARS‐CoV‐2 Omicron variant BA.1 harbours 35 mutations in its Spike protein from the original SARS‐CoV‐2 variant that emerged late 2019. Soon…”
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Transient imine directing groups for the C-H functionalisation of aldehydes, ketones and amines: an update 2018-2020 by Higham, Joe I, Bull, James A

“…The use of pre-installed directing groups has become a popular and powerful strategy to control site selectivity in transition metal catalysed C-H…”
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Quantification of spatial and phenotypic heterogeneity in an agent-based model of tumour-macrophage interactions by Bull, Joshua A, Byrne, Helen M

“…We introduce a new spatial statistic, the weighted pair correlation function (wPCF). The wPCF extends the existing pair correlation function (PCF) and…”
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Synthesis of Sulfoximines and Sulfonimidamides Using Hypervalent Iodine Mediated NH Transfer by Luisi, Renzo, Bull, James A

“…The development of NH transfer reactions using hypervalent iodine and simple sources of ammonia has facilitated the synthesis of sulfoximines and…”
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Transfer of Electrophilic NH Using Convenient Sources of Ammonia: Direct Synthesis of NH Sulfoximines from Sulfoxides by Zenzola, Marina, Doran, Robert, Degennaro, Leonardo, Luisi, Renzo, Bull, James A.

“…A new system for NH transfer is developed for the preparation of sulfoximines, which are emerging as valuable motifs for drug discovery. The protocol employs…”
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Broadly-Neutralizing Antibodies Against Emerging SARS-CoV-2 Variants by Shrestha, Lok Bahadur, Tedla, Nicodemus, Bull, Rowena A.

“…The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have become a major concern in the containment of current pandemic. The…”
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Thermal Stability and Explosive Hazard Assessment of Diazo Compounds and Diazo Transfer Reagents by Green, Sebastian P, Wheelhouse, Katherine M, Payne, Andrew D, Hallett, Jason P, Miller, Philip W, Bull, James A

“…Despite their wide use in academia as metal-carbene precursors, diazo compounds are often avoided in industry owing to concerns over their instability,…”
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Development and assessment of a higher-spatial-resolution (4.4 km) MISR aerosol optical depth product using AERONET-DRAGON data by Garay, Michael J, Kalashnikova, Olga V, Bull, Michael A

“…Since early 2000, the Multi-angle Imaging SpectroRadiometer (MISR) instrument on NASA's Terra satellite has been acquiring data that have been used to produce…”
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Regio- and Stereospecific Synthesis of C‑3 Functionalized Proline Derivatives by Palladium Catalyzed Directed C(sp3)–H Arylation by Affron, Dominic P, Davis, Owen A, Bull, James A

“…Functionalization of C­(sp3)–H bonds at the unactivated 3-position of proline derivatives has been achieved using aryl iodides and palladium catalysis. This…”
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Analytical validity of nanopore sequencing for rapid SARS-CoV-2 genome analysis by Bull, Rowena A., Adikari, Thiruni N., Ferguson, James M., Hammond, Jillian M., Stevanovski, Igor, Beukers, Alicia G., Naing, Zin, Yeang, Malinna, Verich, Andrey, Gamaarachchi, Hasindu, Kim, Ki Wook, Luciani, Fabio, Stelzer-Braid, Sacha, Eden, John-Sebastian, Rawlinson, William D., van Hal, Sebastiaan J., Deveson, Ira W.

“…Viral whole-genome sequencing (WGS) provides critical insight into the transmission and evolution of Severe Acute Respiratory Syndrome Coronavirus 2…”
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Real-Time Interface Algorithm for Ankle Kinematics and Stiffness From Electromyographic Signals by Dimitrov, H., Bull, A. M. J., Farina, D.

“…Shortcomings in capabilities of below-knee (transtibial) prostheses, compared to their biological counterparts, still cause medical complications and…”
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Myocardial Stiffness in Patients With Heart Failure and a Preserved Ejection Fraction: Contributions of Collagen and Titin by Zile, Michael R, Baicu, Catalin F, S. Ikonomidis, John, Stroud, Robert E, Nietert, Paul J, Bradshaw, Amy D, Slater, Rebecca, Palmer, Bradley M, Van Buren, Peter, Meyer, Markus, M. Redfield, Margaret, A. Bull, David, L. Granzier, Henk, LeWinter, Martin M

“…BACKGROUND—The purpose of this study was to determine whether patients with heart failure and a preserved ejection fraction (HFpEF) have an increase in passive…”
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Rapid evolution of pandemic noroviruses of the GII.4 lineage by Bull, Rowena A, Eden, John-Sebastian, Rawlinson, William D, White, Peter A

“…Over the last fifteen years there have been five pandemics of norovirus (NoV) associated gastroenteritis, and the period of stasis between each pandemic has…”
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Palladium-Catalyzed Directed C(sp3)-H Arylation of Saturated Heterocycles at C-3 Using a Concise Optimization Approach by Affron, Dominic P., Bull, James A.

“…Saturated heterocycles, such as THFs, pyrrolidines, piperidines and THPs, are essential components of many biologically active compounds. Examples of C–H…”
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Mathematical modelling reveals cellular dynamics within tumour spheroids by Bull, Joshua A, Mech, Franziska, Quaiser, Tom, Waters, Sarah L, Byrne, Helen M

“…Tumour spheroids are widely used as an in vitro assay for characterising the dynamics and response to treatment of different cancer cell lines. Their…”
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Synthesis of Sulfoximine Carbamates by Rhodium-Catalyzed Nitrene Transfer of Carbamates to Sulfoxides by Zenzola, Marina, Doran, Robert, Luisi, Renzo, Bull, James A

“…Sulfoximines are of considerable interest for incorporation into medicinal compounds. A convenient synthesis of N-protected sulfoximines is achieved, under…”
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An open source lower limb model: Hip joint validation by Modenese, L, Phillips, A.T.M, Bull, A.M.J

“…Abstract Musculoskeletal lower limb models have been shown to be able to predict hip contact forces (HCFs) that are comparable to in vivo measurements obtained…”
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Introducing the 4.4 km spatial resolution Multi-Angle Imaging SpectroRadiometer (MISR) aerosol product by Garay, Michael J, Witek, Marcin L, Kahn, Ralph A, Seidel, Felix C, Limbacher, James A, Bull, Michael A, Diner, David J, Hansen, Earl G, Kalashnikova, Olga V, Lee, Huikyo, Nastan, Abigail M, Yu, Yan

“…The Multi-angle Imaging SpectroRadiometer (MISR) instrument has been operational on the National Aeronautics and Space Administration (NASA) Earth Observing…”
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Synthesis of Di-, Tri-, and Tetrasubstituted Oxetanes by Rhodium-Catalyzed OH Insertion and CC Bond-Forming Cyclization by Davis, Owen A., Bull, James A.

“…Oxetanes offer exciting potential as structural motifs and intermediates in drug discovery and materials science. Here an efficient strategy for the synthesis…”
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Palladium‐Catalyzed C(sp3)−H Arylation of Primary Amines Using a Catalytic Alkyl Acetal to Form a Transient Directing Group by St John‐Campbell, Sahra, Ou, Alex K., Bull, James A.

“…C−H Functionalization of amines is a prominent challenge due to the strong complexation of amines to transition metal catalysts, and therefore typically…”
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