Search Results - "Bulbake, Upendra"
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1
Liposomal Formulations in Clinical Use: An Updated Review
Published in Pharmaceutics (27-03-2017)“…Liposomes are the first nano drug delivery systems that have been successfully translated into real-time clinical applications. These closed bilayer…”
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Chitosan sponges as a sustained release carrier system for the prophylaxis of orthopedic implant-associated infections
Published in International journal of biological macromolecules (01-08-2019)“…The present investigation aims to study the chitosan sponge as a carrier matrix for the sustained antibiotic release system for the prophylaxis of orthopedic…”
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3
Therapeutic Macromolecular Iron Chelators
Published in Current medicinal chemistry (01-01-2019)“…Iron is a key element for every single living process. On a fundamental level, targeting iron is a valuable approach for the treatment of disorders caused by…”
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Preparation, characterization, and in vivo evaluation of cyclosporine cationic liposomes for the treatment of psoriasis
Published in Journal of liposome research (02-01-2020)“…Cyclosporine (CYC), a calcineurin inhibitor acts specifically on T-cells and is one of the most effective treatment options for psoriasis. Systemic…”
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Cabazitaxel and thymoquinone co-loaded lipospheres as a synergistic combination for breast cancer
Published in Chemistry and physics of lipids (01-11-2019)“…[Display omitted] •Cabazitaxel(CBZ) as microtubule inhibitor and thymoquinone (TMQ) as HDAC inhibitor affects the important genes like p53, STAT3, Bax, BCL-2,…”
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6
Liposphere mediated topical delivery of Thymoquinone in the treatment of psoriasis
Published in Nanomedicine (01-10-2017)“…Abstract Thymoquinone (TMQ) is reported with good anti-psoriatic activity however, the hydrophobicity, poor aqueous solubility, light and pH sensitive nature…”
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Comparison of cationic liposome and PAMAM dendrimer for delivery of anti-Plk1 siRNA in breast cancer treatment
Published in Pharmaceutical development and technology (02-01-2020)“…Delivery of negatively charged, high molecular weight and unstable siRNA is difficult. The present study describes the development and comparison of cationic…”
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Cationic liposomes for co-delivery of paclitaxel and anti-Plk1 siRNA to achieve enhanced efficacy in breast cancer
Published in Journal of drug delivery science and technology (01-12-2018)“…Combined effects of anticancer drug and siRNA have shown superior advantages for cancer chemotherapy. Herein, we analyzed the feasibility whether anticancer…”
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Validated stability indicating assay method of olaparib: LC-ESI-Q-TOF-MS/MS and NMR studies for characterization of its new hydrolytic and oxidative forced degradation products
Published in Journal of pharmaceutical and biomedical analysis (25-10-2018)“…[Display omitted] •Olaperib is used to treat prostate, ovarian and breast cancer in the patients with hereditary BRCA1 and BRCA2 mutations.•This is the first…”
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Preparation and Comparison of Oral Bioavailability for Different Nano-formulations of Olaparib
Published in AAPS PharmSciTech (06-08-2019)“…Olaparib (OLA) is a poly ADP ribose polymerase (PARP) inhibitor approved for germline BRCA-mutated (gBRCAm) advanced ovarian cancer and breast cancer. Low oral…”
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11
Curcumin loaded biomimetic composite graft for faster regeneration of skin in diabetic wounds
Published in Journal of drug delivery science and technology (01-10-2018)“…Diabetic wounds do not heal in an organized and timely manner due to poor blood glucose control and weakened immune system. In the present study, wound healing…”
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