Search Results - "Bukur, Juergen"

The role of classical and non-classical HLA class I antigens in human tumors by Bukur, Juergen, Jasinski, Simon, Seliger, Barbara

“…Abstract In human tumors alterations in the surface expression and/or function of the major histocompatibility complex (MHC) class I antigens are frequently…”
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Clinical relevance of the tumor microenvironment and immune escape of oral squamous cell carcinoma by Eckert, Alexander W, Wickenhauser, Claudia, Salins, Paul C, Kappler, Matthias, Bukur, Juergen, Seliger, Barbara

“…Changes in the tumor microenvironment and immune surveillance represent crucial hallmarks of various kinds of cancer, including oral squamous cell carcinoma…”
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Correction to: Clinical relevance of the tumor microenvironment and immune escape of oral squamous cell carcinoma by Eckert, Alexander W, Wickenhauser, Claudia, Salins, Paul C, Kappler, Matthias, Bukur, Juergen, Seliger, Barbara

“…The original version of this article [1], published on 5 April 2016, contains a mistake. In the 'Role of pH stabilisation' section, "intracellular pH" has been…”
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Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma by Seliger, Barbara, Handke, Diana, Schabel, Elisabeth, Bukur, Juergen, Lichtenfels, Rudolf, Dammann, Reinhard

“…The ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) gene involved in the regulation of cellular ubiquitin levels plays an important role in different cellular…”
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Identification and characterization of human leukocyte antigen class I ligands in renal cell carcinoma cells by Seliger, Barbara, Dressler, Sven P., Massa, Chiara, Recktenwald, Christian V., Altenberend, Florian, Bukur, Juergen, Marincola, Francesco M., Wang, Ena, Stevanovic, Stefan, Lichtenfels, Rudolf

“…The presentation of tumor antigen‐derived peptides by human leukocyte antigen (HLA) class I surface antigens on tumor cells is a key prerequisite to trigger…”
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Multiparametric immune profiling in HPV– oral squamous cell cancer by Feng, Zipei, Bethmann, Daniel, Kappler, Matthias, Ballesteros-Merino, Carmen, Eckert, Alexander, Bell, R. Bryan, Cheng, Allen, Bui, Tuan, Leidner, Rom, Urba, Walter J., Johnson, Kent, Hoyt, Clifford, Bifulco, Carlo B., Bukur, Juergen, Wickenhauser, Claudia, Seliger, Barbara, Fox, Bernard A.

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Tumor-induced escape mechanisms and their association with resistance to checkpoint inhibitor therapy by Friedrich, Michael, Jasinski-Bergner, Simon, Lazaridou, Maria-Filothei, Subbarayan, Karthikeyan, Massa, Chiara, Tretbar, Sandy, Mueller, Anja, Handke, Diana, Biehl, Katharina, Bukur, Jürgen, Donia, Marco, Mandelboim, Ofer, Seliger, Barbara

“…Immunotherapy aims to activate the immune system to fight cancer in a very specific and targeted manner. Despite the success of different immunotherapeutic…”
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HLA-E expression and its clinical relevance in human renal cell carcinoma by Seliger, Barbara, Jasinski-Bergner, Simon, Quandt, Dagmar, Stoehr, Christine, Bukur, Juergen, Wach, Sven, Legal, Wolfgang, Taubert, Helge, Wullich, Bernd, Hartmann, Arndt

“…The non-classical human leukocyte antigen E (HLA-E) expression is frequently overexpressed in tumor diseases, transplants and virus-infected cells and…”
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TGF-β inducible epithelial-to-mesenchymal transition in renal cell carcinoma by Tretbar, Sandy, Krausbeck, Peter, Müller, Anja, Friedrich, Michael, Vaxevanis, Christoforos, Bukur, Juergen, Jasinski-Bergner, Simon, Seliger, Barbara

“…Epithelial-to-mesenchymal transition (EMT) is a crucial step in cancer progression and the number one reason for poor prognosis and worse overall survival of…”
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Identification of E2F1 as an Important Transcription Factor for the Regulation of Tapasin Expression by Bukur, Juergen, Herrmann, Felix, Handke, Diana, Recktenwald, Christian, Seliger, Barbara

“…HER-2/neu overexpression in tumor cells caused abnormalities of MHC class I surface expression due to impaired expression of components of the…”
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Multiparametric immune profiling in HPV- oral squamous cell cancer by Feng, Zipei, Bethmann, Daniel, Kappler, Matthias, Ballesteros-Merino, Carmen, Eckert, Alexander, Bell, R Bryan, Cheng, Allen, Bui, Tuan, Leidner, Rom, Urba, Walter J, Johnson, Kent, Hoyt, Clifford, Bifulco, Carlo B, Bukur, Juergen, Wickenhauser, Claudia, Seliger, Barbara, Fox, Bernard A

“…Evaluation of T lymphocyte frequency provides prognostic information for patients with oral squamous cell cancer (OSCC). However, the effect of simultaneously…”
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PD57-06 ALTERED IMMUNE CELL REPERTOIRE AND ACTIVITY AFTER CHECKPOINT BLOCKADE IMMUNOTHERAPY WITH NIVOLUMAB IN RENAL CELL CARCINOMA by Spek, Annabel, Massa, Chiara, Bethmann, Daniel, Bukur, Juergen, Mueller, Anja, Wickenhauser, Claudia, Fox, Bernard, Seliger, Barbara, Staehler, Michael

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Association of IFN-γ Signal Transduction Defects with Impaired HLA Class I Antigen Processing in Melanoma Cell Lines by RESPA, Annedore, BUKUR, Juergen, FERRONE, Soldano, PAWELEC, Graham, YINGDONG ZHAO, WANG, Ena, MARINCOLA, Francesco M, SELIGER, Barbara

“…Abnormalities in the constitutive and IFN-γ-inducible HLA class I surface antigen expression of tumor cells is often associated with an impaired expression of…”
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Clinical relevance of miR-mediated HLA-G regulation and the associated immune cell infiltration in renal cell carcinoma by Jasinski-Bergner, Simon, Stoehr, Christine, Bukur, Juergen, Massa, Chiara, Braun, Juliane, Hüttelmaier, Stefan, Spath, Verena, Wartenberg, Roland, Legal, Wolfgang, Taubert, Helge, Wach, Sven, Wullich, Bernd, Hartmann, Arndt, Seliger, Barbara

“…In human tumors of distinct origin including renal cell carcinoma (RCC), the non-classical human leukocyte antigen G (HLA-G) is frequently expressed, thereby…”
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Distinct Molecular Mechanisms of Altered HLA Class II Expression in Malignant Melanoma by Meyer, Stefanie, Handke, Diana, Mueller, Anja, Biehl, Katharina, Kreuz, Markus, Bukur, Jürgen, Koehl, Ulrike, Lazaridou, Maria-Filothei, Berneburg, Mark, Steven, André, Massa, Chiara, Seliger, Barbara

“…Background: The human leukocyte antigen (HLA) class II molecules are constitutively expressed in some melanoma, but the underlying molecular mechanisms have…”
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ITOC2 – 009. Role of signal transduction and microRNAs on the immunogenicity of melanoma cells by Stefanie, Meyer, Marco, Donia, Diana, Handke, Anja, Müller, Anne, Meinhardt, Simon, Jasinski-Bergner, Juergen, Bukur

“…Melanoma is a heterogeneous malignancy with a distinct clinical outcome of patients due to different genetic features and various strategies of melanoma cells…”
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Abstract 4087: Identification of microRNAs involved in shaping immune surveillance and growth properties of tumors by Seliger, Barbara, Jasinski-Bergner, Simon, Bukur, Juergen, Schulz, Kristin, Stehle, Franziska

“…Ligands of the natural killer (NK) cells and CD8+ cytotoxic T lymphocyte (CTL) receptors, such as the inhibitory classical HLA-G antigen, are often deregulated…”
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HER-2/neu mediates oncogenic transformation via altered CREB expression and function by Steven, André, Leisz, Sandra, Massa, Chiara, Iezzi, Manuela, Lattanzio, Rossano, Lamolinara, Alessia, Bukur, Jürgen, Müller, Anja, Hiebl, Bernhard, Holzhausen, Hans-Jürgen, Seliger, Barbara

“…The cyclic (c)AMP responsive element binding protein (CREB) plays a key role in many cellular processes, including differentiation, proliferation, and signal…”
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“Tumor immunology meets oncology (TIMO) VII” from 15th to 16th of April 2011 in Halle/Saale, Germany by Bukur, Juergen, Noessner, Elfriede, Seliger, Barbara

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Modulation of MHC class I surface expression in B16F10 melanoma cells by methylseleninic acid by Lennicke, Claudia, Rahn, Jette, Bukur, Jürgen, Hochgräfe, Falko, Wessjohann, Ludger A., Lichtenfels, Rudolf, Seliger, Barbara

“…The essential trace element selenium (Se) might play a role in cancer prevention as well as for cancer therapy. Its metabolite methylselenol is able to kill…”
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