Search Results - "Bukhari, Nadeem Irfan"
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Advances in nano-delivery systems for doxorubicin: an updated insight
Published in Journal of drug targeting (21-04-2018)“…Doxorubicin (DOX) is the most effective chemotherapeutic drug developed against broad range of cancers such as solid tumours, transplantable leukemias and…”
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Determination of Bergenin in Different Parts of Bergenia ciliata using a Validated RP-HPLC Method
Published in Natural product sciences (2021)“…Bergenia ciliata (Family: Saxifragaceae) is a folklore remedy for the treatment of various ailments in Asian countries. Bergenin (1) has been isolated as an…”
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Determination of Bergenin in Different Parts of Bergenia ciliata using a Validated RP-HPLC Method
Published in Natural product sciences (2021)“…Bergenia ciliata (Family: Saxifragaceae) is a folklore remedy for the treatment of various ailments in Asian countries. Bergenin (1) has been isolated as an…”
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Characterization and gastroprotective effects of Rosa brunonii Lindl. fruit on gastric mucosal injury in experimental rats – A preliminary study
Published in Acta biochimica polonica (18-08-2023)“…Gastric ulcer is the most prevalent disorder affecting a large population. Rosa brunonii Lindl. fruit (RBF) has traditionally been used to treat stomach pains…”
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Advancements in the oral delivery of Docetaxel: challenges, current state-of-the-art and future trends
Published in International journal of nanomedicine (01-01-2018)“…The oral delivery of cancer chemotherapeutic drugs is challenging due to low bioavailability, gastrointestinal side effects, first-pass metabolism and…”
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Doxorubicin-loaded quaternary ammonium palmitoyl glycol chitosan polymeric nanoformulation: uptake by cells and organs
Published in International journal of nanomedicine (01-01-2019)“…This study was aimed to develop doxorubicin-loaded quaternary ammonium palmitoyl glycol chitosan (DOX-GCPQ) nanoformulation that could enable DOX delivery and…”
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Phylogenetic diversity and mutational analysis of New Delhi Metallo-β-lactamase (NDM) producing E. coli strains from pediatric patients in Pakistan
Published in Saudi journal of biological sciences (01-10-2021)“…The evolution of NDM genes (blaNDM) in E. coli is accounted for expansive multidrug resistance (MDR), causing severe infections and morbidities in the…”
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Lipodendriplexes mediated enhanced gene delivery: a cellular to pre-clinical investigation
Published in Scientific reports (08-12-2020)“…Clinical success of effective gene therapy is mainly hampered by the insufficiency of safe and efficient internalization of a transgene to the targeted…”
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Is folklore use of Euphorbia helioscopia devoid of toxic effects?
Published in Drug and chemical toxicology (New York, N.Y. 1978) (02-04-2016)“…Objective: To evaluate acute toxic effects of Euphorbia helioscopia in order to assure the safety and usefulness of herbal remedy. Materials and methods: The…”
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Academia-pharmaceutical industry linkage: An academic perspective
Published in Journal of pharmaceutical policy and practice (2024)“…The pharmaceutical sector in Pakistan has grown over a period, however, there are several barriers in the framework governing the growth of the country's…”
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Safety and Pharmaceutical Evaluation of a Novel Natural Polymer, Ocicum, as Solubility and Dissolution Enhancer in Solid Dispersion
Published in Pharmaceuticals (Basel, Switzerland) (14-07-2022)“…Plant mucilages are commonly employed as excipients in pharmaceutical manufacturing. Ocimum basilicum (Lamiaceae family), a source of hydrophilic mucilage…”
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Influence of Quercetin Pretreatment on Pharmacokinetics of Warfarin in Rats
Published in Current drug safety (01-01-2023)“…Warfarin (WAR) is an anticoagulant with a narrow therapeutic index and is principally metabolized by CYP3A4 and CYP2C9 enzymes. The inhibitors of these enzymes…”
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13
Precise and Sensitive Ambient Temperature Based Analytical Colorimetric Method for Pregabalin
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2022)“…Abstract Pregabalin, a GABA analogue is used to treat epilepsy and neuropathic pain. The drug poses problems in analytical quantification when estimated at a…”
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Vaccine Prices: A Systematic Review of Literature
Published in Vaccines (Basel) (29-10-2020)“…Vaccines are among the most vital interventions to control and reduce the morbidity and mortality worldwide. In accessing vaccines, pricing is usually the…”
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Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System of Raloxifene with Improved Solubility and Oral Bioavailability
Published in Pharmaceutics (01-08-2023)“…Poor aqueous solubility and dissolution limit the oral bioavailability of Biopharmaceutics Classification System (BCS) class II drugs. In this study, we aimed…”
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Prediction of lisinopril pediatric dose from the reference adult dose by employing a physiologically based pharmacokinetic model
Published in BMC pharmacology & toxicology (29-07-2020)“…Abstract Background This study aimed to assess the pediatric lisinopril doses using an adult physiological based pharmacokinetic (PBPK) model. As the empirical…”
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Acid Uric 3× Tablet: Standardization and pharmacological evidence of uric acid use as anti-gout medicine
Published in Journal of pharmacy & pharmacognosy research (01-11-2020)“…Context: Despite being a causative agent of gout, uric acid is used as an anti-gout medicine in homeopathy without reported scientific evidence, and such…”
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Chemical and pharmacological comparison of modern and traditional dosage forms of Joshanda
Published in Natural product research (19-03-2019)“…Recently, a traditional remedy (Joshanda) has been replaced largely by modern ready-to-use dosage forms, which have not been compared to the original remedy…”
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Cross verification of prescribing trends through loop evaluation of physicians, patients and medical store personnel
Published in BMC health services research (22-05-2019)“…Prescription connects physician, patient and community pharmacy personnel who can help in understanding prescribing pattern. The present study was aimed to get…”
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Cell to rodent: toxicological profiling of folate grafted thiomer enveloped nanoliposomes
Published in Toxicology research (Cambridge) (01-11-2017)“…Polymeric nanomaterials, hybridized with lipid components, e.g. phosphocholine or fatty acids, are currently being explored for efficient nano-platforms for…”
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