Search Results - "Bukhari, Maurish"
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Fibroblast activation protein drives tumor metastasis via a protease-independent role in invadopodia stabilization
Published in Cell reports (Cambridge) (31-10-2023)“…During metastasis, tumor cells invade through the basement membrane and intravasate into blood vessels and then extravasate into distant organs to establish…”
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Journal Article -
2
KCa3.1-dependent uptake of the cytotoxic DNA-binding dye Hoechst 33258 into cancerous but not healthy cervical cells
Published in The Journal of biological chemistry (01-01-2021)“…The poor and nonselective penetration of current chemotherapeutics across the plasma membranes of cancer cells, which is necessary for the targeted disruption…”
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Journal Article -
3
Utilization of Ion Channels to Enhance Permeation of Chemotherapeutic Drugs; and the Role Intermediate Conductance Calcium Activated Potassium Channel KCa3.1 in Cervical Squamous Cell Carcinoma in vitro
Published 01-01-2019“…Cancer is one of the leading causes of morbidity worldwide. Despite years of therapeutic progress, many challenges persist in the quest for developing…”
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Dissertation -
4
Extracellular ATP stimulates uptake of a topoisomerase poison into cervical cancer cells
Published in The FASEB journal (01-04-2015)“…Abstract only…”
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Journal Article -
5
Measurement of relative Ca2+ permeability during sustained activation of TRPV1 receptors
Published in Pflügers Archiv (01-02-2016)“…Some cation permeable ligand-gated ion channels, including the capsaicin-sensitive TRPV1, have been reported to exhibit a time-dependent increase in…”
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Journal Article -
6
Measurement of relative Ca^sup 2+^ permeability during sustained activation of TRPV1 receptors
Published in Pflügers Archiv (01-02-2016)“…Some cation permeable ligand-gated ion channels, including the capsaicin-sensitive TRPV1, have been reported to exhibit a time-dependent increase in…”
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Journal Article -
7
Ion channel-mediated uptake of cationic vital dyes into live cells: a potential source of error when assessing cell viability
Published in Cell biology and toxicology (01-10-2016)“…Ionic “vital dyes” are commonly used to assess cell viability based on the idea that their permeation is contingent on a loss of membrane integrity. However,…”
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Journal Article -
8
K Ca 3.1-dependent uptake of the cytotoxic DNA-binding dye Hoechst 33258 into cancerous but not healthy cervical cells
Published in The Journal of biological chemistry (01-01-2021)“…The poor and nonselective penetration of current chemotherapeutics across the plasma membranes of cancer cells, which is necessary for the targeted disruption…”
Get full text
Journal Article -
9
K Ca 3.1-dependent uptake of the cytotoxic DNA-binding dye Hoechst 33258 into cancerous but not healthy cervical cells
Published in The Journal of biological chemistry (23-11-2020)“…The poor and nonselective penetration of current chemotherapeutics across the plasma membranes of cancer cells, which is necessary for the targeted disruption…”
Get full text
Journal Article -
10
Selective permeabilization of cervical cancer cells to an ionic DNA-binding cytotoxin by activation of P2Y receptors
Published in FEBS letters (04-06-2015)“…•ATP stimulated uptake of the cytotoxin, Hoechst 33258, into cervical epithelial cells.•The mechanism was dependent on P2Y receptors and independent of P2X7…”
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Journal Article -
11
Membrane activity of a supramolecular peptide-based chemotherapeutic enhancer
Published in Molecular bioSystems (16-08-2016)“…Self-assembly of de novo designed multidomain peptides (MDPs) resulted in functional membrane-active supramolecular nanofibers. The membrane activity was…”
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Journal Article