Outcomes of COVID-19: Disparities by ethnicity

To investigate the role of ethnicity in COVID-19 outcome disparities in a cohort in Kuwait. This is a retrospective analysis of 405 individuals infected with SARS-CoV-2 in Kuwait. Outcomes such as symptoms severity and mortality were considered. Multivariate logistic regression models were used to r...

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Published in:Infection, genetics and evolution Vol. 87; p. 104639
Main Authors: Ali, Hamad, Alshukry, Abdullah, Marafie, Sulaiman K., AlRukhayes, Monera, Ali, Yaseen, Abbas, Mohammad Bu, Al-Taweel, Abdullah, Bukhamseen, Yousef, Dashti, Mohammad H., Al-Shammari, Abdullah A., Abu-Farha, Mohammad, AbuBakr, Jehad, Al-Mulla, Fahd
Format: Journal Article
Language:English
Published: Netherlands Elsevier B.V 01-01-2021
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Summary:To investigate the role of ethnicity in COVID-19 outcome disparities in a cohort in Kuwait. This is a retrospective analysis of 405 individuals infected with SARS-CoV-2 in Kuwait. Outcomes such as symptoms severity and mortality were considered. Multivariate logistic regression models were used to report the odds ratios (OR) for ICU admission and dying from COVID-19. The cohort included 290 Arabs and 115 South Asians. South Asians recorded significantly higher COVID-19 death rates compared to Arabs (33% vs. 7.6%, P value<0.001). When compared to Arabs, South Asians also had higher odds of being admitted to the ICU (OR = 6.28, 95% CI: 3.34–11.80, p < 0.001). South Asian patients showed 7.62 (95% CI: 3.62–16.02, p < 0.001) times the odds of dying from COVID-19. COVID-19 patients with South Asians ethnicity in Kuwait are more likely to have worse prognosis and outcome when compared to patients with Arab ethnicity. This suggest a possible role for ethnicity in COVID-19 outcome disparities and this role is likely to be multifactorial. •Kuwait is a multiethnic country with a population of 4.3 million made mostly by Arabs and South Asians.•South Asians were more likely to develop a severe form of the disease which also corresponded to a higher death rate compared to Arabs in Kuwait.•Results highlighted probable impact of ethnicity on COVID-19 outcome.
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ISSN:1567-1348
1567-7257
DOI:10.1016/j.meegid.2020.104639