Search Results - "Buitendijk, Gabrielle H.S."

Visual Consequences of Refractive Errors in the General Population by Verhoeven, Virginie J.M., MD, Wong, King T., MD, Buitendijk, Gabriëlle H.S., MD, Hofman, Albert, MD, PhD, Vingerling, Johannes R., MD, PhD, Klaver, Caroline C.W., MD, PhD

“…Objective To study the frequency and causes of visual impairment in relation to refractive error. Design Population-based cohort study. Participants A total of…”
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Lipids, Lipid Genes, and Incident Age-Related Macular Degeneration: The Three Continent Age-Related Macular Degeneration Consortium by Klein, Ronald, Myers, Chelsea E, Buitendijk, Gabriëlle H.S, Rochtchina, Elena, Gao, Xiaoyi, de Jong, Paulus T.V.M, Sivakumaran, Theru A, Burlutsky, George, McKean-Cowdin, Roberta, Hofman, Albert, Iyengar, Sudha K, Lee, Kristine E, Stricker, Bruno H, Vingerling, Johannes R, Mitchell, Paul, Klein, Barbara E.K, Klaver, Caroline C.W, Wang, Jie Jin

“…Purpose To describe associations of serum lipid levels and lipid pathway genes to the incidence of age-related macular degeneration (AMD). Design…”
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Genetic Susceptibility, Dietary Antioxidants, and Long-Term Incidence of Age-Related Macular Degeneration in Two Populations by Wang, Jie Jin, MMed, PhD, Buitendijk, Gabriëlle H.S., MD, MSc, Rochtchina, Elena, BSc, MAppStat, Lee, Kristine E., MS, Klein, Barbara E.K., MD, MPH, van Duijn, Cornelia M., PhD, Flood, Victoria M., MPH, PhD, Meuer, Stacy M., BS, Attia, John, MD, PhD, Myers, Chelsea, MStat, Holliday, Elizabeth G., PhD, Tan, Ava G., MAIT, MPH, Smith, Wayne T., MBBS, PhD, Iyengar, Sudha K., PhD, de Jong, Paulus T.V.M., MD, PhD, Hofman, Albert, MD, PhD, Vingerling, Johannes R., MD, PhD, Mitchell, Paul, MD, PhD, Klein, Ronald, MD, MPH, Klaver, Caroline C.W., MD, PhD

“…Objective To examine effect modification between genetic susceptibility to age-related macular degeneration (AMD) and dietary antioxidant or fish consumption…”
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CAMK2-Dependent Signaling in Neurons Is Essential for Survival by Kool, Martijn J., Proietti Onori, Martina, Borgesius, Nils Z., van de Bree, Jolet E., Elgersma-Hooisma, Minetta, Nio, Enzo, Bezstarosti, Karel, Buitendijk, Gabriëlle H.S., Aghadavoud Jolfaei, Mehrnoush, Demmers, Jeroen A.A., Elgersma, Ype, van Woerden, Geeske M.

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Association of Axial Length With Risk of Uncorrectable Visual Impairment for Europeans With Myopia by Tideman, J Willem L, Snabel, Margaretha C C, Tedja, Milly S, van Rijn, Gwyneth A, Wong, King T, Kuijpers, Robert W A M, Vingerling, Johannes R, Hofman, Albert, Buitendijk, Gabriëlle H S, Keunen, Jan E E, Boon, Camiel J F, Geerards, Annette J M, Luyten, Gregorius P M, Verhoeven, Virginie J M, Klaver, Caroline C W

“…Myopia (ie, nearsightedness) is becoming the most common eye disorder to cause blindness in younger persons in many parts of the world. Visual impairment due…”
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αCaMKII Is Essential for Cerebellar LTD and Motor Learning by Hansel, Christian, de Jeu, Marcel, Belmeguenai, Amor, Houtman, Simone H., Buitendijk, Gabriëlle H.S., Andreev, Dmitri, De Zeeuw, Chris I., Elgersma, Ype

“…Activation of postsynaptic α-calcium/calmodulin-dependent protein kinase II (αCaMKII) by calcium influx is a prerequisite for the induction of long-term…”
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High Bone Mineral Density and Fracture Risk in Type 2 Diabetes as Skeletal Complications of Inadequate Glucose Control: The Rotterdam Study by OEI, Ling, ZILLIKENS, M. Carola, HOFMAN, Albert, VAN LEEUWEN, Johannes P. T. M, WITTEMAN, Jacqueline C. M, POLS, Huibert A. P, UITTERLINDEN, André G, KLAVER, Caroline C. W, FRANCO, Oscar H, RIVADENEIRA, Fernando, DEHGHAN, Abbas, BUITENDIJK, GabriËlle H. S, CASTANO-BETANCOURT, Martha C, ESTRADA, Karol, STOLK, Lisette, OEI, Edwin H. G, VAN MEURS, Joyce B. J, JANSSEN, Joseph A. M. J. L

“…Individuals with type 2 diabetes have increased fracture risk despite higher bone mineral density (BMD). Our aim was to examine the influence of glucose…”
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βCaMKII plays a nonenzymatic role in hippocampal synaptic plasticity and learning by targeting αCaMKII to synapses by Borgesius, Nils Z, van Woerden, Geeske M, Buitendijk, Gabrielle H S, Keijzer, Nanda, Jaarsma, Dick, Hoogenraad, Casper C, Elgersma, Ype

“…The calcium/calmodulin-dependent kinase type II (CaMKII) holoenzyme of the forebrain predominantly consists of heteromeric complexes of the αCaMKII and βCaMKII…”
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A functional variant in the CFI gene confers a high risk of age-related macular degeneration by van de Ven, Johannes P H, Nilsson, Sara C, Tan, Perciliz L, Buitendijk, Gabriëlle H S, Ristau, Tina, Mohlin, Frida C, Nabuurs, Sander B, Schoenmaker-Koller, Frederieke E, Smailhodzic, Dzenita, Campochiaro, Peter A, Zack, Donald J, Duvvari, Maheswara R, Bakker, Bjorn, Paun, Codrut C, Boon, Camiel J F, Uitterlinden, Andre G, Liakopoulos, Sandra, Klevering, B Jeroen, Fauser, Sascha, Daha, Mohamed R, Katsanis, Nicholas, Klaver, Caroline C W, Blom, Anna M, Hoyng, Carel B, den Hollander, Anneke I

“…Johannes van de Ven and colleagues report a rare missense mutation in CFI encoding a p.Gly119Arg substitution that confers a high risk of AMD. Sera from AMD…”
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High Bone Mineral Density and Fracture Risk in Type 2 Diabetes as Skeletal Complications of Inadequate Glucose Control by Oei, Ling, Zillikens, M. Carola, Dehghan, Abbas, Buitendijk, Gabriëlle H.S., Castaño-Betancourt, Martha C., Estrada, Karol, Stolk, Lisette, Oei, Edwin H.G., van Meurs, Joyce B.J., Janssen, Joseph A.M.J.L., Hofman, Albert, van Leeuwen, Johannes P.T.M., Witteman, Jacqueline C.M., Pols, Huibert A.P., Uitterlinden, André G., Klaver, Caroline C.W., Franco, Oscar H., Rivadeneira, Fernando

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Prediction of Age-related Macular Degeneration in the General Population by Buitendijk, Gabriëlle H.S., MD, MSc, Rochtchina, Elena, MApplStat, Myers, Chelsea, MStat, van Duijn, Cornelia M., PhD, Lee, Kristine E., MS, Klein, Barbara E.K., MD, MPH, Meuer, Stacy M., BS, de Jong, Paulus T.V.M., MD, PhD, Holliday, Elizabeth G., PhD, Tan, Ava G., MAIT, MPH, Uitterlinden, André G., PhD, Sivakumaran, Theru S., PhD, Attia, John, MD, PhD, Hofman, Albert, MD, PhD, Mitchell, Paul, MD, PhD, Vingerling, Johannes R., PhD, Iyengar, Sudha K., PhD, Janssens, A. Cecile J.W., PhD, Wang, Jie Jin, MMed, PhD, Klein, Ronald, MD, MPH, Klaver, Caroline C.W., MD, PhD

“…Purpose Prediction models for age-related macular degeneration (AMD) based on case-control studies have a tendency to overestimate risks. The aim of this study…”
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Quality of life: fractionated stereotactic radiotherapy versus enucleation treatment in uveal melanoma patients by Beek, Jackelien G.M., Buitendijk, Gabrielle H.S., Timman, Reinier, Muller, Karin, Luyten, Gregorius P.M., Paridaens, Dion, Naus, Nicole C., Kiliç, Emine

“…Purpose To report the quality of life and visual functioning in uveal melanoma patients treated with enucleation or fractionated stereotactic radiation therapy…”
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Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients by van Beveren, Nico J M, Buitendijk, Gabrielle H S, Swagemakers, Sigrid, Krab, Lianne C, Röder, Christian, de Haan, Lieuwe, van der Spek, Peter, Elgersma, Ype

“…Recent studies have suggested that deregulated AKT1 signaling is associated with schizophrenia. We hypothesized that if this is indeed the case, we should…”
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Analysis of rare variants in the C3 gene in patients with age-related macular degeneration by Duvvari, Maheswara R, Paun, Codrut C, Buitendijk, Gabriëlle H S, Saksens, Nicole T M, Volokhina, Elena B, Ristau, Tina, Schoenmaker-Koller, Frederieke E, van de Ven, Johannes P H, Groenewoud, Joannes M M, van den Heuvel, Lambertus P W J, Hofman, Albert, Fauser, Sascha, Uitterlinden, André G, Klaver, Caroline C W, Hoyng, Carel B, de Jong, Eiko K, den Hollander, Anneke I

“…Age-related macular degeneration (AMD) is a progressive retinal disorder affecting over 33 million people worldwide. Genome-wide association studies (GWASs)…”
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Prevalence of Age-Related Macular Degeneration in Europe: The Past and the Future by Colijn, Johanna M, Buitendijk, Gabriëlle H S, Prokofyeva, Elena, Alves, Dalila, Cachulo, Maria L, Khawaja, Anthony P, Cougnard-Gregoire, Audrey, Merle, Bénédicte M J, Korb, Christina, Erke, Maja G, Bron, Alain, Anastasopoulos, Eleftherios, Meester-Smoor, Magda A, Segato, Tatiana, Piermarocchi, Stefano, de Jong, Paulus T V M, Vingerling, Johannes R, Topouzis, Fotis, Creuzot-Garcher, Catherine, Bertelsen, Geir, Pfeiffer, Norbert, Fletcher, Astrid E, Foster, Paul J, Silva, Rufino, Korobelnik, Jean-François, Delcourt, Cécile, Klaver, Caroline C W

“…Age-related macular degeneration (AMD) is a frequent, complex disorder in elderly of European ancestry. Risk profiles and treatment options have changed…”
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Sifting the wheat from the chaff: prioritizing GWAS results by identifying consistency across analytical methods by Oldmeadow, Christopher, Riveros, Carlos, Holliday, Elizabeth G., Scott, Rodney, Moscato, Pablo, Wang, Jie Jin, Mitchell, Paul, Buitendijk, Gabrielle H.S., Vingerling, Johannes R., Klaver, Caroline C.W., Klein, Ronald, Attia, John

“…The curse of multiple testing has led to the adoption of a stringent Bonferroni threshold for declaring genome‐wide statistical significance for any one SNP as…”
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Seven new loci associated with age-related macular degeneration by Fritsche, Lars G, Chen, Wei, Schu, Matthew, Yaspan, Brian L, Yu, Yi, Thorleifsson, Gudmar, Zack, Donald J, Arakawa, Satoshi, Cipriani, Valentina, Ripke, Stephan, Igo, Jr, Robert P, Buitendijk, Gabriëlle H S, Sim, Xueling, Weeks, Daniel E, Guymer, Robyn H, Merriam, Joanna E, Francis, Peter J, Hannum, Gregory, Agarwal, Anita, Armbrecht, Ana Maria, Audo, Isabelle, Aung, Tin, Barile, Gaetano R, Benchaboune, Mustapha, Bird, Alan C, Bishop, Paul N, Branham, Kari E, Brooks, Matthew, Brucker, Alexander J, Cade, William H, Cain, Melinda S, Campochiaro, Peter A, Chan, Chi-Chao, Cheng, Ching-Yu, Chew, Emily Y, Chin, Kimberly A, Chowers, Itay, Clayton, David G, Cojocaru, Radu, Conley, Yvette P, Cornes, Belinda K, Daly, Mark J, Dhillon, Baljean, Edwards, Albert O, Evangelou, Evangelos, Fagerness, Jesen, Ferreyra, Henry A, Friedman, James S, Geirsdottir, Asbjorg, George, Ronnie J, Gieger, Christian, Gupta, Neel, Hagstrom, Stephanie A, Harding, Simon P, Haritoglou, Christos, Heckenlively, John R, Holz, Frank G, Hughes, Guy, Ioannidis, John P A, Ishibashi, Tatsuro, Joseph, Peronne, Jun, Gyungah, Kamatani, Yoichiro, Katsanis, Nicholas, N Keilhauer, Claudia, Khan, Jane C, Kim, Ivana K, Kiyohara, Yutaka, Klein, Barbara E K, Klein, Ronald, Kovach, Jaclyn L, Kozak, Igor, Lee, Clara J, Lee, Kristine E, Lichtner, Peter, Lotery, Andrew J, Meitinger, Thomas, Mitchell, Paul, Mohand-Saïd, Saddek, Moore, Anthony T, Morgan, Denise J, Morrison, Margaux A, Myers, Chelsea E, Naj, Adam C, Nakamura, Yusuke, Okada, Yukinori, Orlin, Anton, Ortube, M Carolina, Othman, Mohammad I, Pappas, Chris, Park, Kyu Hyung, Pauer, Gayle J T, Peachey, Neal S, Poch, Olivier, Priya, Rinki Ratna, Reynolds, Robyn, Richardson, Andrea J, Ripp, Raymond, Rudolph, Guenther, Ryu, Euijung

“…Gonçalo Abecasis and colleagues report a large-scale meta-analysis of genome-wide association studies for age-related macular degeneration (AMD), including…”
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Prevalence of refractive error in Europe: the European Eye Epidemiology (E³) Consortium by Williams, Katie M., Verhoeven, Virginie J. M., Cumberland, Phillippa, Bertelsen, Geir, Wolfram, Christian, Buitendijk, Gabriëlle H. S., Hofman, Albert, van Duijn, Cornelia M., Vingerling, Johannes R., Kuijpers, Robert W. A. M., Höhn, René, Mirshahi, Alireza, Khawaja, Anthony P., Luben, Robert N., Erke, Maja Gran, von Hanno, Therese, Mahroo, Omar, Hogg, Ruth, Gieger, Christian, Cougnard-Grégoire, Audrey, Anastasopoulos, Eleftherios, Bron, Alain, Dartigues, Jean-François, Korobelnik, Jean-François, Creuzot-Garcher, Catherine, Topouzis, Fotis, Delcourt, Cécile, Rahi, Jugnoo, Meitinger, Thomas, Fletcher, Astrid, Foster, Paul J., Pfeiffer, Norbert, Klaver, Caroline C. W., Hammond, Christopher J.

“…To estimate the prevalence of refractive error in adults across Europe. Refractive data (mean spherical equivalent) collected between 1990 and 2013 from…”
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Retinal neurodegeneration and brain MRI markers: the Rotterdam Study by Mutlu, Unal, Bonnemaijer, Pieter W.M., Ikram, M. Arfan, Colijn, Johanna M., Cremers, Lotte G.M., Buitendijk, Gabriëlle H.S., Vingerling, Johannes R., Niessen, Wiro J., Vernooij, Meike W., Klaver, Caroline C.W., Ikram, M. Kamran

“…We investigated the association of specific retinal sublayer thicknesses on optical coherence tomography (OCT) with brain magnetic resonance imaging (MRI)…”
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CAMK2-Dependent Signaling in Neurons Is Essential for Survival by Kool, Martijn J, Proietti Onori, Martina, Borgesius, Nils Z, van de Bree, Jolet E, Elgersma-Hooisma, Minetta, Nio, Enzo, Bezstarosti, Karel, Buitendijk, Gabriëlle H S, Aghadavoud Jolfaei, Mehrnoush, Demmers, Jeroen A A, Elgersma, Ype, van Woerden, Geeske M

“…Ca /calmodulin-dependent protein kinase II (CAMK2) is a key player in synaptic plasticity and memory formation. Mutations in or cause intellectual disability…”
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