Search Results - "Bui, Tam T.T."

Spectroscopic Studies on Nicotine and Nornicotine in the UV Region by Clayton, Peter M., Vas, Carl A., Bui, Tam T.T., Drake, Alex F., McAdam, Kevin

“…ABSTRACT The UV absorption and electronic circular dichroism (ECD) spectra of (R)‐ and (S)‐nicotine and (S)‐nornicotine in aqueous solution were measured to a…”
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Solution Model of the Intrinsically Disordered Polyglutamine Tract-Binding Protein-1 by Rees, Martin, Gorba, Christian, de Chiara, Cesira, Bui, Tam T.T., Garcia-Maya, Mitla, Drake, Alex F., Okazawa, Hitoshi, Pastore, Annalisa, Svergun, Dmitri, Chen, Yu Wai

“…Polyglutamine tract-binding protein-1 (PQBP-1) is a 265-residue nuclear protein that is involved in transcriptional regulation. In addition to its role in the…”
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Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase by Abis, Giancarlo, Pacheco-Gómez, Raúl, Bui, Tam T. T, Conte, Maria R

“…Isothermal titration calorimetry (ITC) is conventionally used to acquire thermodynamic data for biological interactions. In recent years, ITC has emerged as a…”
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Tightening of gelatin chemically crosslinked networks assisted by physical gelation by da Silva, Marcelo A., Kang, Jie, Bui, Tam T. T., da Silva, Lisa M. Borges, Burn, Jake, Keddie, Joseph L., Dreiss, Cécile A.

“…ABSTRACT Developing the use of polymers from renewable sources to build hydrogels with tailored mechanical properties has become an increasing focus of…”
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The p73 DNA Binding Domain Displays Enhanced Stability Relative to Its Homologue, the Tumor Suppressor p53, and Exhibits Cooperative DNA Binding by Patel, Seema, Bui, Tam T.T, Drake, Alex F, Fraternali, Franca, Nikolova, Penka V

“…The p53 protein family is involved in the control of an intricate network of genes implicated in cell cycle, through to germ line integrity and development…”
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Multiple protein interactions involving proposed extracellular loop domains of the tight junction protein occludin by Nusrat, Asma, Brown, G Thomas, Tom, Jeffrey, Drake, Alex, Bui, Tam T T, Quan, Cliff, Mrsny, Randall J

“…Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that is projected to have two extracellular…”
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Chiral Polymer-Carbon-Nanotube Composite Nanofibers by Zhang, X., Song, W., Harris, P. J. F., Mitchell, G. R., Bui, T. T. T., Drake, A. F.

“…Optically active polyaniline–carbon‐nanotube nanocomposites are synthesized by using a solution‐chemistry method. The stereochemical selectivity of the…”
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Structure and catalytic activity of some soluble polyethylene glycol–peptide conjugates by Kelly, David R., Bui, Tam T.T., Caroff, Eva, Drake, Alex F., Roberts, Stanley M.

“…Graphic Soluble catalysts for the Juliá–Colonna asymmetric epoxidation reaction have been constructed in three different ways, using NH 2-PEG-OMe as the…”
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A Versatile Virus‐Mimetic Engineering Approach for Concurrent Protein Nanocage Surface‐Functionalization and Cargo Encapsulation by Sheng, Yujie, Chen, Zilong, Cherrier, Mickael V, Martin, Lydie, Bui, Tam T. T., Li, Wei, Lynham, Steven, Nicolet, Yvain, Ebrahimi, Kourosh H.

“…Naturally occurring protein nanocages like ferritin are self‐assembled from multiple subunits. Because of their unique cage‐like structure and…”
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LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA by Cruz-Gallardo, Isabel, Martino, Luigi, Kelly, Geoff, Atkinson, R Andrew, Trotta, Roberta, De Tito, Stefano, Coleman, Pierre, Ahdash, Zainab, Gu, Yifei, Bui, Tam T T, Conte, Maria R

“…Abstract LARP4A belongs to the ancient RNA-binding protein superfamily of La-related proteins (LARPs). In humans, it acts mainly by stabilizing mRNAs,…”
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Binding Interactions of Peptide Aptamers by New, Roger R C, Bui, Tam T T, Bogus, Michal

“…Peptide aptamers are short amino acid chains that are capable of binding specifically to ligands in the same way as their much larger counterparts, antibodies…”
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Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module by Martino, Luigi, Pennell, Simon, Kelly, Geoff, Busi, Baptiste, Brown, Paul, Atkinson, R Andrew, Salisbury, Nicholas J H, Ooi, Zi-Hao, See, Kang-Wei, Smerdon, Stephen J, Alfano, Caterina, Bui, Tam T T, Conte, Maria R

“…The La-related proteins (LARPs) form a diverse group of RNA-binding proteins characterized by the possession of a composite RNA binding unit, the La module…”
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Zinc-induced oligomerization of zinc α2 glycoprotein reveals multiple fatty acid-binding sites by Zahid, Henna, Miah, Layeque, Lau, Andy M, Brochard, Lea, Hati, Debolina, Bui, Tam T T, Drake, Alex F, Gor, Jayesh, Perkins, Stephen J, McDermott, Lindsay C

“…Zinc α2 glycoprotein (ZAG) is an adipokine with a class I MHC protein fold and is associated with obesity and diabetes. Although its intrinsic ligand remains…”
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Consequences of point mutations in melanoma-associated antigen 4 (MAGE-A4) protein: Insights from structural and biophysical studies by Hagiwara, Yoshio, Sieverling, Lina, Hanif , Farina, Anton, Jensy, Dickinson, Eleanor R., Bui, Tam T. T., Andreeva, Antonina, Barran, Perdita E., Cota, Ernesto, Nikolova, Penka V.

“…The Melanoma-Associated Antigen A4 (MAGE-A4) protein is a target for cancer therapy. The function of this protein is not well understood. We report the first…”
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Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La protein by Martino, Luigi, Pennell, Simon, Kelly, Geoff, Bui, Tam T. T., Kotik-Kogan, Olga, Smerdon, Stephen J., Drake, Alex F., Curry, Stephen, Conte, Maria R.

“…Human La protein is an essential factor in the biology of both coding and non-coding RNAs. In the nucleus, La binds primarily to 3′ oligoU containing RNAs,…”
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Strong and weak zinc binding sites in human zinc-α2-glycoprotein by Kumar, Aditya Arun, Hati, Debolina, Thaker, Thana’a Mohajer, Miah, Layeque, Cunningham, Phil, Domene, Carmen, Bui, Tam T.T., Drake, Alex F., McDermott, Lindsay C.

“…•Zinc-α2-glycoprotein (ZAG) is an adipokine.•ZAG has one strong zinc binding site and up to 15 weak zinc binding sites.•The strong zinc binding site is…”
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Structure and stability insights into tumour suppressor p53 evolutionary related proteins by Pagano, Bruno, Jama, Abdullah, Martinez, Pierre, Akanho, Ester, Bui, Tam T T, Drake, Alex F, Fraternali, Franca, Nikolova, Penka V

“…The p53 family of genes and their protein products, namely, p53, p63 and p73, have over one billion years of evolutionary history. Advances in computational…”
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Observation of a Single-Stranded DNA/Pyrrolobenzodiazepine Adduct by Rahman, Khondaker M, James, Colin H, Bui, Tam T. T, Drake, Alex F, Thurston, David E

“…Pyrrolobenzodiazepine (PBD) antitumor agents have, to date, only been observed to bind to duplex DNA, apparently requiring a minor groove environment for…”
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Pyrrolobenzodiazepines (PBDs) do not bind to DNA G-quadruplexes by Rahman, Khondaker M, Corcoran, David B, Bui, Tam T T, Jackson, Paul J M, Thurston, David E

“…The pyrrolo[2,1-c][1,4] benzodiazepines (PBDs) are a family of sequence-selective, minor-groove binding DNA-interactive agents that covalently attach to…”
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Ridge-Tile-like Chiral Topology: Synthesis, Resolution, and Complete Chiroptical Characterization of Enantiomers of Edge-Sharing Binuclear Square Planar Complexes of Ni(II) Bearing Achiral Ligands by Soloshonok, Vadim A, Ono, Taizo, Ueki, Hisanori, Vanthuyne, Nicolas, Balaban, Teodor Silviu, Bürck, Jochen, Fliegl, Heike, Klopper, Wim, Naubron, Jean-Valère, Bui, Tam T. T, Drake, Alex F, Roussel, Christian

“…Binuclear square planar Ni(II) complexes are described, formed by two tridentate ligands with two imine-nitrogens coordinating two nickel atoms. Such complexes…”
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