Search Results - "Bui, Tam T. T"

Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase by Abis, Giancarlo, Pacheco-Gómez, Raúl, Bui, Tam T. T, Conte, Maria R

“…Isothermal titration calorimetry (ITC) is conventionally used to acquire thermodynamic data for biological interactions. In recent years, ITC has emerged as a…”
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Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography by Nkansah, Edwin, Shah, Rahi, Collie, Gavin W., Parkinson, Gary N., Palmer, Jonathan, Rahman, Khondaker M., Bui, Tam T., Drake, Alex F., Husby, Jarmila, Neidle, Stephen, Zinzalla, Giovanna, Thurston, David E., Wilderspin, Andrew F.

“…► Stoichiometric uSTAT3 interaction with M67 DNA. ► Interaction is weaker compared to pSTAT3 M67 DNA interaction. ► Report of a novel protein electrophoretic…”
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Binding Interactions of Peptide Aptamers by New, Roger R C, Bui, Tam T T, Bogus, Michal

“…Peptide aptamers are short amino acid chains that are capable of binding specifically to ligands in the same way as their much larger counterparts, antibodies…”
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Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module by Martino, Luigi, Pennell, Simon, Kelly, Geoff, Busi, Baptiste, Brown, Paul, Atkinson, R Andrew, Salisbury, Nicholas J H, Ooi, Zi-Hao, See, Kang-Wei, Smerdon, Stephen J, Alfano, Caterina, Bui, Tam T T, Conte, Maria R

“…The La-related proteins (LARPs) form a diverse group of RNA-binding proteins characterized by the possession of a composite RNA binding unit, the La module…”
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Pyrrolobenzodiazepines (PBDs) do not bind to DNA G-quadruplexes by Rahman, Khondaker M, Corcoran, David B, Bui, Tam T T, Jackson, Paul J M, Thurston, David E

“…The pyrrolo[2,1-c][1,4] benzodiazepines (PBDs) are a family of sequence-selective, minor-groove binding DNA-interactive agents that covalently attach to…”
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Land inequality or productivity: What mattered in Southern Vietnam after 1975? by Bui, Minh‐Tam T., Preechametta, Arayah

“…Land redistribution and agricultural collective production were the key components of agrarian reforms implemented by the Vietnamese Communist Party in the…”
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Observation of a Single-Stranded DNA/Pyrrolobenzodiazepine Adduct by Rahman, Khondaker M, James, Colin H, Bui, Tam T. T, Drake, Alex F, Thurston, David E

“…Pyrrolobenzodiazepine (PBD) antitumor agents have, to date, only been observed to bind to duplex DNA, apparently requiring a minor groove environment for…”
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Ridge-Tile-like Chiral Topology: Synthesis, Resolution, and Complete Chiroptical Characterization of Enantiomers of Edge-Sharing Binuclear Square Planar Complexes of Ni(II) Bearing Achiral Ligands by Soloshonok, Vadim A, Ono, Taizo, Ueki, Hisanori, Vanthuyne, Nicolas, Balaban, Teodor Silviu, Bürck, Jochen, Fliegl, Heike, Klopper, Wim, Naubron, Jean-Valère, Bui, Tam T. T, Drake, Alex F, Roussel, Christian

“…Binuclear square planar Ni(II) complexes are described, formed by two tridentate ligands with two imine-nitrogens coordinating two nickel atoms. Such complexes…”
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Analysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La protein by Martino, Luigi, Pennell, Simon, Kelly, Geoff, Bui, Tam T. T., Kotik-Kogan, Olga, Smerdon, Stephen J., Drake, Alex F., Curry, Stephen, Conte, Maria R.

“…Human La protein is an essential factor in the biology of both coding and non-coding RNAs. In the nucleus, La binds primarily to 3′ oligoU containing RNAs,…”
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Structure and stability insights into tumour suppressor p53 evolutionary related proteins by Pagano, Bruno, Jama, Abdullah, Martinez, Pierre, Akanho, Ester, Bui, Tam T T, Drake, Alex F, Fraternali, Franca, Nikolova, Penka V

“…The p53 family of genes and their protein products, namely, p53, p63 and p73, have over one billion years of evolutionary history. Advances in computational…”
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Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights by Merabet, Assia, Houlleberghs, Hellen, Maclagan, Kate, Akanho, Ester, Bui, Tam T T, Pagano, Bruno, Drake, Alex F, Fraternali, Franca, Nikolova, Penka V

“…To assess the potential of mutations from the L1 loop of the tumour suppressor p53 as second-site suppressors, the effect of H115N and S116M on the p53 'hot…”
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Spectroscopic Studies on Nicotine and Nornicotine in the UV Region by Clayton, Peter M., Vas, Carl A., Bui, Tam T.T., Drake, Alex F., McAdam, Kevin

“…ABSTRACT The UV absorption and electronic circular dichroism (ECD) spectra of (R)‐ and (S)‐nicotine and (S)‐nornicotine in aqueous solution were measured to a…”
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15-deoxy-Δ12,14-Prostaglandin J2 inhibits human soluble epoxide hydrolase by a dual orthosteric and allosteric mechanism by Abis, Giancarlo, Charles, Rebecca L., Kopec, Jolanta, Yue, Wyatt W., Atkinson, R. Andrew, Bui, Tam T. T., Lynham, Steven, Popova, Simona, Sun, Yin-Biao, Fraternali, Franca, Eaton, Philip, Conte, Maria R.

“…Human soluble epoxide hydrolase (hsEH) is an enzyme responsible for the inactivation of bioactive epoxy fatty acids, and its inhibition is emerging as a…”
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A Versatile Virus‐Mimetic Engineering Approach for Concurrent Protein Nanocage Surface‐Functionalization and Cargo Encapsulation by Sheng, Yujie, Chen, Zilong, Cherrier, Mickael V, Martin, Lydie, Bui, Tam T. T., Li, Wei, Lynham, Steven, Nicolet, Yvain, Ebrahimi, Kourosh H.

“…Naturally occurring protein nanocages like ferritin are self‐assembled from multiple subunits. Because of their unique cage‐like structure and…”
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Lipid–Peptide Vesicle Nanoscale Hybrids for Triggered Drug Release by Mild Hyperthermia in Vitro and in Vivo by Al-Ahmady, Zahraa S, Al-Jamal, Wafa’ T, Bossche, Jeroen V, Bui, Tam T, Drake, Alex F, Mason, A. James, Kostarelos, Kostas

“…The present study describes leucine zipper peptide–lipid hybrid nanoscale vesicles engineered by self-assembled anchoring of the amphiphilic peptide within the…”
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Solution Model of the Intrinsically Disordered Polyglutamine Tract-Binding Protein-1 by Rees, Martin, Gorba, Christian, de Chiara, Cesira, Bui, Tam T.T., Garcia-Maya, Mitla, Drake, Alex F., Okazawa, Hitoshi, Pastore, Annalisa, Svergun, Dmitri, Chen, Yu Wai

“…Polyglutamine tract-binding protein-1 (PQBP-1) is a 265-residue nuclear protein that is involved in transcriptional regulation. In addition to its role in the…”
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The p73 DNA Binding Domain Displays Enhanced Stability Relative to Its Homologue, the Tumor Suppressor p53, and Exhibits Cooperative DNA Binding by Patel, Seema, Bui, Tam T.T, Drake, Alex F, Fraternali, Franca, Nikolova, Penka V

“…The p53 protein family is involved in the control of an intricate network of genes implicated in cell cycle, through to germ line integrity and development…”
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LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA by Cruz-Gallardo, Isabel, Martino, Luigi, Kelly, Geoff, Atkinson, R Andrew, Trotta, Roberta, De Tito, Stefano, Coleman, Pierre, Ahdash, Zainab, Gu, Yifei, Bui, Tam T T, Conte, Maria R

“…Abstract LARP4A belongs to the ancient RNA-binding protein superfamily of La-related proteins (LARPs). In humans, it acts mainly by stabilizing mRNAs,…”
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Antimicrobial Peptide Potency is Facilitated by Greater Conformational Flexibility when Binding to Gram-negative Bacterial Inner Membranes by Amos, Sarah-Beth T. A., Vermeer, Louic S., Ferguson, Philip M., Kozlowska, Justyna, Davy, Matthew, Bui, Tam T., Drake, Alex F., Lorenz, Christian D., Mason, A. James

“…The interaction of antimicrobial peptides (AMPs) with the inner membrane of Gram-negative bacteria is a key determinant of their abilities to exert diverse…”
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Temporin L and aurein 2.5 have identical conformations but subtly distinct membrane and antibacterial activities by Manzo, Giorgia, Ferguson, Philip M., Hind, Charlotte K., Clifford, Melanie, Gustilo, V. Benjamin, Ali, Hind, Bansal, Sukhvinder S., Bui, Tam T., Drake, Alex F., Atkinson, R. Andrew, Sutton, J. Mark, Lorenz, Christian D., Phoenix, David A., Mason, A. James

“…Frogs such as Rana temporaria and Litoria aurea secrete numerous closely related antimicrobial peptides (AMPs) as an effective chemical dermal defence. Damage…”
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