Search Results - "Bui, Nghiem"

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety by Thomas, Alexia, Burant, April, Bui, Nghiem, Graham, Deanna, Yuva-Paylor, Lisa A., Paylor, Richard

“…Rationale An increasing number of investigators utilize the marble-burying assay despite the paucity of information available regarding what underlies the…”
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Group I metabotropic glutamate receptor antagonists alter select behaviors in a mouse model for fragile X syndrome by Thomas, Alexia M., Bui, Nghiem, Perkins, Jennifer R., Yuva-Paylor, Lisa A., Paylor, Richard

“…Rationale Studies in the Fmr1 knockout (KO) mouse, a model of fragile X syndrome (FXS), suggest that excessive signaling through group I metabotropic glutamate…”
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Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome by Thomas, Alexia M., Bui, Nghiem, Graham, Deanna, Perkins, Jennifer R., Yuva-Paylor, Lisa A., Paylor, Richard

“…► mGluR1 genetic reduction decreased Fmr1 KO locomotor activity. ► mGluR5 genetic reduction alters KO analgesic responses and active social behavior. ►…”
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Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome by Veeraragavan, Surabi, Bui, Nghiem, Perkins, Jennie R., Yuva-Paylor, Lisa A., Carpenter, Randall L., Paylor, Richard

“…Rationale Muscarinic acetylcholine receptors (mAChR) are G protein-coupled receptors, widely expressed in the CNS. Electrophysiological and molecular studies…”
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The Modulation of Fragile X Behaviors by the Muscarinic M4 Antagonist, Tropicamide by Veeraragavan, Surabi, Bui, Nghiem, Perkins, Jennie R, Yuva-Paylor, Lisa A, Paylor, Richard

“…Muscarinic acetylcholine receptors (mAChR) are G protein-coupled receptors (M1-M5), grouped together into two functional classes, based on their G protein…”
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Onset and progression of behavioral and molecular phenotypes in a novel congenic R6/2 line exhibiting intergenerational CAG repeat stability by Cowin, Randi-Michelle, Bui, Nghiem, Graham, Deanna, Green, Jennie R, Grueninger, Stephan, Yuva-Paylor, Lisa A, Syed, Arsalan U, Weiss, Andreas, Paylor, Richard

“…In the present study we report on the use of speed congenics to generate a C57BL/6J congenic line of HD-model R6/2 mice carrying 110 CAG repeats, which…”
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Genetic background modulates behavioral impairments in R6/2 mice and suggests a role for dominant genetic modifiers in Huntington’s disease pathogenesis by Cowin, Randi-Michelle, Bui, Nghiem, Graham, Deanna, Green, Jennie R, Yuva-Paylor, Lisa A, Weiss, Andreas, Paylor, Richard

“…Variability and modification of the symptoms of Huntington’s disease (HD) are commonly observed in both patient populations and animal models of the disease…”
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Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS) by Veeraragavan, Surabi, Graham, Deanna, Bui, Nghiem, Yuva-Paylor, Lisa A, Wess, Jürgen, Paylor, Richard

“…The G-protein coupled muscarinic acetylcholine receptors, widely expressed in the CNS, have been implicated in fragile X syndrome (FXS). Recent studies have…”
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Genetic reduction of muscarinic M 4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS) by Veeraragavan, Surabi, Graham, Deanna, Bui, Nghiem, Yuva-Paylor, Lisa A., Wess, Jürgen, Paylor, Richard

“…► M 4 receptor modulates select fragile X behaviors. ► Genetic reduction of M 4 rescued the analgesic response. ► Genetic reduction of M 4 partly rescued the…”
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Neuronal aggregates are associated with phenotypic onset in the R6/2 Huntington's disease transgenic mouse by Cowin, Randi-Michelle, Roscic, Ana, Bui, Nghiem, Graham, Deanna, Paganetti, Paolo, Jankowsky, Joanna L., Weiss, Andreas, Paylor, Richard

“…► Age of onset is delayed with increasing CAG repeat length in congenic C57BL6/J R6/2 HD model mice. ► Lower repeat lengths correlate with higher transgene…”
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Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of Fragile × Syndrome (F×S) by Veeraragavan, Surabi, Graham, Deanna, Bui, Nghiem, Yuva-Paylor, Lisa A, Wess, Jürgen, Paylor, Richard

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Modulation of behavioral phenotypes by a muscarinic Ml antagonist in a mouse model of fragile X syndrome by VEERARAGAVAN, Surabi, BUI, Nghiem, PERKINS, Jennie R, YUVA-PAYLOR, Lisa A, CARPENTER, Randall L, PAYLOR, Richard

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