Search Results - "Bui, Christine B."
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Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities
Published in Nature communications (13-11-2020)“…Necrotizing enterocolitis (NEC) is a severe, currently untreatable intestinal disease that predominantly affects preterm infants and is driven by poorly…”
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Interleukin-1 Receptor Antagonist Protects Newborn Mice Against Pulmonary Hypertension
Published in Frontiers in immunology (11-07-2019)“…Pulmonary hypertension secondary to bronchopulmonary dysplasia (BPD-PH) represents a major complication of BPD in extremely preterm infants for which there are…”
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Refining anti‐inflammatory therapy strategies for bronchopulmonary dysplasia
Published in Journal of cellular and molecular medicine (01-06-2017)“…Bronchopulmonary dysplasia (BPD) is a severe lung disease of preterm infants, which is characterized by fewer, enlarged alveoli and increased inflammation. BPD…”
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Pulmonary hypertension associated with bronchopulmonary dysplasia in preterm infants
Published in Journal of reproductive immunology (01-11-2017)“…•Pulmonary inflammation disrupts vascular and alveolar development in BPD-PH.•Off-label use of sildenafil may improve echocardiographic markers of…”
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IL-37 increases in patients after ischemic stroke and protects from inflammatory brain injury, motor impairment and lung infection in mice
Published in Scientific reports (06-05-2019)“…Post-stroke inflammation may contribute to secondary brain injury and systemic immunosuppression. Interleukin(IL)-37 is an immunosuppressive cytokine belonging…”
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Type 2 immune polarization is associated with cardiopulmonary disease in preterm infants
Published in Science translational medicine (06-04-2022)“…Postnatal maturation of the immune system is poorly understood, as is its impact on illnesses afflicting term or preterm infants, such as bronchopulmonary…”
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