Search Results - "Buhl, A. M."

Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients by Gunnarsson, R, Isaksson, A, Mansouri, M, Göransson, H, Jansson, M, Cahill, N, Rasmussen, M, Staaf, J, Lundin, J, Norin, S, Buhl, A M, Smedby, K E, Hjalgrim, H, Karlsson, K, Jurlander, J, Juliusson, G, Rosenquist, R

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The CLLU1 expression level is a stable and inherent feature of the chronic lymphocytic leukemia clone by Buhl, A M, Novotny, G W, Josefsson, P, Nielsen, J E, Pedersen, L B, Geisler, C, Rassenti, L Z, Kipps, T J, Jurlander, J, Leffers, H

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FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase by Worthen, G S, Avdi, N, Buhl, A M, Suzuki, N, Johnson, G L

“…Chemoattractants bind to seven transmembrane-spanning, G-protein-linked receptors on polymorphonuclear leukocytes (neutrophils) and induce a variety of…”
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B-cell antigen receptor competence regulates B-lymphocyte selection and survival by Buhl, A M, Nemazee, D, Cambier, J C, Rickert, R, Hertz, M

“…Experimental evidence contradicts the simplistic view that during development all B cells expressing non autoreactive antigen receptors on the cell surface are…”
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Mapping of the C5a Receptor Signal Transduction Network in Human Neutrophils by Buhl, Anne Mette, Avdi, Natalie, Worthen, G. Scott, Johnson, Gary L.

“…Human neutrophils respond to chemoattractants, resulting in their accumulation at an inflammatory site. Chemoattractants such as the C5a peptide, derived from…”
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Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia by GUNNARSSON, Rebeqa, MANSOURI, Larry, SMEDBY, Karin Ekström, HJALGRIM, Henrik, KARLSSON, Karin, JURLANDER, Jesper, GEISLER, Christian, JULIUSSON, Gunnar, ROSENQUIST, Richard, ISAKSSON, Anders, GÖRANSSON, Hanna, CAHILL, Nicola, JANSSON, Mattias, RASMUSSEN, Markus, LUNDIN, Jeanette, NORIN, Stefan, BUHL, Anne Mette

“…High-resolution genomic microarrays enable simultaneous detection of copy-number aberrations such as the known recurrent aberrations in chronic lymphocytic…”
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LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia by Kaderi, Mohd Arifin, Kanduri, Meena, Buhl, Anne Mette, Sevov, Marie, Cahill, Nicola, Gunnarsson, Rebeqa, Jansson, Mattias, Smedby, Karin Ekström, Hjalgrim, Henrik, Jurlander, Jesper, Juliusson, Gunnar, Mansouri, Larry, Rosenquist, Richard

“…The expression levels of LPL, ZAP70, TCL1A, CLLU1 and MCL1 have recently been proposed as prognostic factors in chronic lymphocytic leukemia. However, few…”
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Phosphorylation of CD19 Y484 and Y515, and Linked Activation of Phosphatidylinositol 3-Kinase, Are Required for B Cell Antigen Receptor-Mediated Activation of Bruton's Tyrosine Kinase by Buhl, Anne Mette, Cambier, John C

“…Bruton's tyrosine kinase (Btk) plays a critical role in B cell Ag receptor (BCR) signaling, as indicated by the X-linked immunodeficiency and X-linked…”
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Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization by Buhl, A M, Pleiman, C M, Rickert, R C, Cambier, J C

“…Genetic ablation of the B cell surface glycoprotein CD19 severely impairs the humoral immune response. This requirement is thought to reflect a critical role…”
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Interleukin-8 Regulation of the Ras/Raf/Mitogen-activated Protein Kinase Pathway in Human Neutrophils () by Knall, Cindy, Young, Scott, Nick, Jerry A., Buhl, Anne Mette, Worthen, G. Scott, Johnson, Gary L.

“…Interleukin-8 (IL-8), the prototypic member of the CXC subfamily of chemokines, induces in neutrophils chemotaxis, the respiratory burst, granule release, and…”
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[d-Arg1,d-Phe5,d-Trp7,9,Leu11]Substance P Acts as a Biased Agonist toward Neuropeptide and Chemokine Receptors by Jarpe, M B, Knall, C, Mitchell, F M, Buhl, A M, Duzic, E, Johnson, G L

“…Substance P derivatives are potential therapeutic compounds for the treatment of small cell lung cancer and can cause apoptosis in small cell lung cancer cells…”
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Co-receptor and accessory regulation of B-cell antigen receptor signal transduction by Buhl, Anne Matte, Cambier, John C.

“…The development and function of the immune system is precisely regulated to assure the generation of protective immune responses while avoiding autoimmunity…”
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CD72‐mediated B cell activation involves recruitment of CD19 and activation of phosphatidylinositol 3‐kinase by Venkataraman, Chandrasekar, Lu, Pei‐Jung, Buhl, Anne Mette, Chen, Ching‐Shih, Cambier, John C., Bondada, Subbarao

“…Occupancy of the B cell glycoprotein, CD72 results in syk‐independent activation of phospholipase‐C γ and calcium mobilization. The cytoplasmic tail of CD72…”
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Selective coupling of the human anaphylatoxin C5a receptor and α 16 in human kidney 293 cells by Buhl, Anne Mette, Eisfelder, Bartholomew J., Worthen, G.Scott, Johnson, Gary L., Russell, Marijane

“…The peptide C5a which is generated during the complement cascade is an important chemotactic factor involved in the inflammatory response. The C5a receptor…”
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CLLU1 expression has prognostic value in chronic lymphocytic leukemia after first-line therapy in younger patients and in those with mutated IGHV genes by Gonzalez, David, Else, Monica, Wren, Dorte, Usai, Monica, Buhl, Anne Mette, Parker, Anton, Oscier, David, Morgan, Gareth, Catovsky, Daniel

“…CLLU1, located at chromosome 12q22, encodes a transcript specific to chronic lymphocytic leukemia and has potential prognostic value. We assessed the value of…”
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Expression of GTPase-deficient G alpha 16 inhibits Swiss 3T3 cell growth by Qian, N X, Russell, M, Buhl, A M, Johnson, G L

“…Expression of the GTPase-deficient G alpha 16 polypeptide G alpha 16Q212L, a member of the Gq family of heterotrimeric G proteins, constitutively activated…”
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IL-8 signal transduction in human neutrophils by Knall, C, Worthen, G S, Buhl, A M, Johnson, G L

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Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia-A comparative study of four differently designed, high resolution microarray platforms by Gunnarsson, Rebeqa, Staaf, Johan, Jansson, Mattias, Ottesen, Anne Marie, Göransson, Hanna, Liljedahl, Ulrika, Ralfkiær, Ulrik, Mansouri, Mahmoud, Buhl, Anne Mette, Smedby, Karin Ekström, Hjalgrim, Henrik, Syvänen, Ann-Christine, Borg, Åke, Isaksson, Anders, Jurlander, Jesper, Juliusson, Gunnar, Rosenquist, Richard

“…Screening for gene copy‐number alterations (CNAs) has improved by applying genome‐wide microarrays, where SNP arrays also allow analysis of loss of…”
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GTP-binding proteins in luminal and basolateral membranes from pars convoluta and pars recta of rabbit kidney proximal tubule by Buhl, Anne Mette, Sheikh, M.Iqbal, Steensgaard, Jens, Røigaard-Petersen, Hans, Jacobsen, Christian

“…The GTP-binding proteins on luminal and basolateral membrane vesicles from outer cortex(pars convoluta) and outer medulla (pars recta) of rabbit proximal…”
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The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein–kinase–dependent mechanism by Pedersen, Irene Munk, Buhl, Anne Mette, Klausen, Pia, Geisler, Christian H., Jurlander, Jesper

“…Antibodies against CD20 can activate complement and induce antibody-dependent cellular cytotoxicity (ADCC) in B lymphocytes. In B-cell lines, such antibodies…”
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