Search Results - "Buharalioglu, C. Kemal"

Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats by Sari, A. Nihal, Kacan, Meltem, Unsal, Demet, Sahan Firat, Seyhan, Kemal Buharalioglu, C., Vezir, Ozden, Korkmaz, Belma, Cuez, Tuba, Canacankatan, Necmiye, Sucu, Nehir, Ayaz, Lokman, Tamer Gumus, Lulufer, Gorur, Aysegul, Tunctan, Bahar

“…The small G protein RhoA and its downstream effector Rho-kinase play an important role in various physiopathological processes including ischemia/reperfusion…”
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Contribution of Vasoactive Eicosanoids and Nitric Oxide Production to the Effect of Selective Cyclooxygenase‐2 Inhibitor, NS‐398, on Endotoxin‐Induced Hypotension in Rats by Tunctan, Bahar, Korkmaz, Belma, Cuez, Tuba, Kemal Buharalioglu, C., Sahan‐Firat, Seyhan, Falck, John, Malik, Kafait U.

“…:  Our previous studies with the use of non‐selective cyclooxygenase (COX) inhibitor, indomethacin, demonstrated that prostanoids produced during endotoxaemia…”
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Piroxicam Reverses Endotoxin‐Induced Hypotension in Rats: Contribution of Vasoactive Eicosanoids and Nitric Oxide by Buharalioglu, C. Kemal, Korkmaz, Belma, Cuez, Tuba, Sahan‐Firat, Seyhan, Sari, Ayse Nihal, Malik, Kafait U., Tunctan, Bahar

“…:  Nitric oxide (NO) produced by inducible NO synthase (iNOS) is responsible for endotoxin‐induced vascular hyporeactivity and hypotension resulting in…”
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Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock by Tunctan, Bahar, Korkmaz, Belma, Sari, Ayse Nihal, Kacan, Meltem, Unsal, Demet, Serin, Mehmet Sami, Buharalioglu, C Kemal, Sahan-Firat, Seyhan, Cuez, Tuba, Schunck, Wolf-Hagen, Manthati, Vijaya L, Falck, John R, Malik, Kafait U

“…We have previously demonstrated that a stable synthetic analog of 20-hydroxyeicosatetraenoic acid (20-HETE), N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine…”
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Effects of 5,14-HEDGE, a 20-HETE mimetic, on lipopolysaccharide-induced changes in MyD88/TAK1/IKKβ/IκB-α/NF-κB pathway and circulating miR-150, miR-223, and miR-297 levels in a rat model of septic shock by Sari, A. Nihal, Korkmaz, Belma, Serin, Mehmet Sami, Kacan, Meltem, Unsal, Demet, Buharalioglu, C. Kemal, Sahan Firat, Seyhan, Manthati, Vijay L., Falck, John R., Malik, Kafait U., Tunctan, Bahar

“…Objectives We have previously demonstrated that a stable synthetic analog of 20-hydroxyeicosatetraenoic acid (20-HETE), N -(20-hydroxyeicosa-5[ Z ],14[ Z…”
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NS-398 reverses hypotension in endotoxemic rats: Contribution of eicosanoids, NO, and peroxynitrite by Tunctan, Bahar, Sari, Ayse Nihal, Kacan, Meltem, Unsal, Demet, Buharalioglu, C. Kemal, Sahan-Firat, Seyhan, Korkmaz, Belma, Falck, John R., Malik, Kafait U.

“…We have previously demonstrated that inhibition of vasodilator prostanoids, PGI2 and PGE2, and nitric oxide (NO) synthesis by a selective cyclooxygenase-2…”
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5,14-HEDGE, a 20-HETE mimetic, reverses hypotension and improves survival in a rodent model of septic shock: Contribution of soluble epoxide hydrolase, CYP2C23, MEK1/ERK1/2/IKKβ/IκB-α/NF-κB pathway, and proinflammatory cytokine formation by Tunctan, Bahar, Korkmaz, Belma, Sari, Ayse Nihal, Kacan, Meltem, Unsal, Demet, Serin, Mehmet Sami, Buharalioglu, C. Kemal, Sahan-Firat, Seyhan, Cuez, Tuba, Schunck, Wolf-Hagen, Falck, John R., Malik, Kafait U.

“…[Display omitted] ► 5,14-HEDGE, a 20-HETE mimetic, reversed hypotension and improved survival. ► 5,14-HEDGE prevented LPS-induced increase in sEH and NF-κB…”
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A Synthetic Analogue of 20‐HETE, 5,14‐HEDGE, Reverses Endotoxin‐Induced Hypotension via Increased 20‐HETE Levels Associated with Decreased iNOS Protein Expression and Vasodilator Prostanoid Production in Rats by Cuez, Tuba, Korkmaz, Belma, Buharalioglu, C. Kemal, Sahan‐Firat, Seyhan, Falck, John, Malik, Kafait U., Tunctan, Bahar

“…:  Nitric oxide (NO) produced by inducible NO synthase (iNOS) is responsible for endotoxin (ET)‐induced hypotension and vascular hyporeactivity and plays a…”
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A 20-hydroxyeicosatetraenoic acid agonist, N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine, opposes the fall in blood pressure and vascular reactivity in endotoxin-treated rats by Tunctan, Bahar, Korkmaz, Belma, Buharalioglu, C Kemal, Firat, Seyhan Sahan, Anjaiah, Siddam, Falck, John, Roman, Richard J, Malik, Kafait U

“…Endotoxic shock is a systemic inflammatory response that is associated with an increase in nitric oxide production and a decrease in the formation of…”
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The effects of bumetanide on human umbilical artery contractions by Dayioglu, Emel, Buharalioglu, C Kemal, Saracoglu, Ferit, Akar, Fatma

“…The authors investigate the effect of bumetan ide, an inhibitor of NKCC1 and a loop diuretic, on the tone of human umbilical artery (HUA). Rings of HUA (n =…”
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The reactivity of serotonin, acetylcholine and kcl-induced contractions to relaxant agents in the rat gastric fundus by Kemal Buharalioğlu, C., Akar, Fatma

“…The effects of nifedipine, cromakalim, diazoxide, caffeine and sodium nitroprusside (SNP) on acetylcholine, serotonin and KCl-induced contractions were studied…”
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Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91phox to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock by Tunctan, Bahar, Korkmaz, Belma, Sari, Ayse Nihal, Kacan, Meltem, Unsal, Demet, Serin, Mehmet Sami, Buharalioglu, C. Kemal, Sahan-Firat, Seyhan, Cuez, Tuba, Schunck, Wolf-Hagen, Manthati, Vijaya L., Falck, John R., Malik, Kafait U.

“…•5,14-HEDGE, a 20-HETE mimetic, reversed hypotension and tachycardia in endotoxemic rats.•5,14-HEDGE prevented LPS-induced increase in expression/activity of…”
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Effects of 5,14-HEDGE, a 20-HETE mimetic, on lipopolysaccharide-induced changes in MyD88/TAK1/IKK[beta]/I[kappa]B-[alpha]/NF-[kappa]B pathway and circulating miR-150, miR-223, and miR-297 levels in a rat model of septic shock by Sari, A Nihal, Korkmaz, Belma, Serin, Mehmet Sami, Kacan, Meltem, Unsal, Demet, Buharalioglu, C Kemal, Sahan Firat, Seyhan, Manthati, Vijay L, Falck, John R, Malik, Kafait U, Tunctan, Bahar

“…We have previously demonstrated that a stable synthetic analog of 20-hydroxyeicosatetraenoic acid (20-HETE), N-(20-hydroxyeicosa-5[Z],14[Z]-dienoyl)glycine…”
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The Characteristics of Contractions to Hyperosmolar Stress in Rat Aorta by Buharaliog, C. Kemal, Ugur, Mehmet, Akar, Fatma

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Reversal of endotoxin-induced hypotension by inhibition of inducible nitric oxide synthase activity is associated with improved oxidative status in rat heart, aorta and mesenteric artery by TAMER, Lülüfer, BUHARALIOĞLU, C. Kemal, KORKMAZ, Belma, ATİK, Uğur, YILDIRIM, Hatice, TUNÇTAN, Bahar

“…Overproduction of reactive oxygen and nitrogen species leads to oxidative stress and decreased total antioxidant capacity, which is responsible for high…”
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Prostaglandins contribute to endotoxin‐induced increase in lipid peroxidation via nitric oxide production during endotoxemia in rats by Sahan‐Firat, Seyhan, Korkmaz, Belma, Cuez, Tuba, Ayaz, Lokman, Tamer, Lulufer, Buharalioglu, C Kemal, Sari, A Nihal, Tunctan, Bahar

“…Abstract only…”
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Differential regulation of oxidative stress by NO in vascular and nonvascular tissues of endotoxemic rats by Sahan‐Firat, Seyhan, Canacankatan, Necmiye, Korkmaz, Belma, Yildirim, Hatice, Tamer, Lulufer, Buharalioglu, C Kemal, Sari, A Nihal, Tunctan, Bahar

“…Abstract only Endotoxemic shock is a systemic inflammatory response that is associated with increased NO production by iNOS which contributes to the fall in…”
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20‐HETE agonist, N‐[20‐hydroxyeicosa‐5(Z),14(Z)‐dienoyl]glycine, opposes the endotoxin‐induced fall in blood pressure and the decrease in vascular reactivity and lipid peroxidation and increased catalase activity via inhibition of NO production in rats by Tunctan, Bahar, Korkmaz, Belma, Buharalioglu, C Kemal, Sahan‐Firat, Seyhan, Anjaiah, Siddam, Falck, John R, Yildirim, Hatice, Tamer, Lulufer, Roman, Richard J, Malik, Kafait U

“…Abstract only Endotoxemic shock is a systemic inflammatory response associated with increased NO production and decreased in the expression and activity of…”
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Studies on the vascular effects of the fractions and phenolic compounds isolated from Viscum album ssp. album by Deliorman, Didem, Çalış, İhsan, Ergun, Fatma, Doğan, B.Sönmez Uydeş, Buharalıoğlu, C.Kemal, Kanzık, İlker

“…Viscum album L. has been used in the indigenous system of medicine for treatment of various diseases such as atherosclerosis and hypertension. In the…”
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Protective effect of cromakalim and diazoxide, and proulcerogenic effect of glibenclamide on indomethacin-induced gastric injury by Akar, Fatma, Uydeş-Doğan, B.Sönmez, Buharalıoğlu, C.Kemal, Gülçin Abban, Heinemann, Akos, Holzer, Peter, Van de Voorde, Johan

“…We investigated the influences of the K + channel opening drugs cromakalim and diazoxide and their blocker, glibenclamide, in indomethacin-induced gastric…”
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