Search Results - "Bugrova, Anna E."
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Potential Urine Proteomic Biomarkers for Focal Segmental Glomerulosclerosis and Minimal Change Disease
Published in International journal of molecular sciences (20-10-2022)“…Primary focal segmental glomerulosclerosis (FSGS), along with minimal change disease (MCD), are diseases with primary podocyte damage that are clinically…”
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Hepatoprotective Activity of Lignin-Derived Polyphenols Dereplicated Using High-Resolution Mass Spectrometry, In Vivo Experiments, and Deep Learning
Published in International journal of molecular sciences (16-12-2022)“…Chronic liver diseases affect more than 1 billion people worldwide and represent one of the main public health issues. Nonalcoholic fatty liver disease (NAFLD)…”
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3
Antitumor Effect of Bleomycin Nanoaerosol in Murine Carcinoma Model
Published in Molecules (Basel, Switzerland) (18-05-2023)“…Bleomycin, which is widely used as an antitumor agent, possesses serious adverse effects such as pulmonary toxicity. Local nanoaerosol deposition for lung…”
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Targeted MRM Quantification of Urinary Proteins in Chronic Kidney Disease Caused by Glomerulopathies
Published in Molecules (Basel, Switzerland) (01-04-2023)“…Glomerulopathies with nephrotic syndrome that are resistant to therapy often progress to end-stage chronic kidney disease (CKD) and require timely and accurate…”
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Quantitative Proteomics of Maternal Blood Plasma in Isolated Intrauterine Growth Restriction
Published in International journal of molecular sciences (01-12-2023)“…Intrauterine growth restriction (IUGR) remains a significant concern in modern obstetrics, linked to high neonatal health problems and even death, as well as…”
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NO-Dependent Mechanisms of Myosin Heavy Chain Transcription Regulation in Rat Soleus Muscle After 7-Days Hindlimb Unloading
Published in Frontiers in physiology (10-07-2020)“…It is known that nitric oxide (NO) may affect myosin heavy chain (MyHC) isoform mRNA transcription in skeletal muscles. The content of NO in soleus muscles…”
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Prognosis of Alzheimer's Disease Using Quantitative Mass Spectrometry of Human Blood Plasma Proteins and Machine Learning
Published in International journal of molecular sciences (18-07-2022)“…Early recognition of the risk of Alzheimer's disease (AD) onset is a global challenge that requires the development of reliable and affordable screening…”
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The Dynamics of β-Amyloid Proteoforms Accumulation in the Brain of a 5xFAD Mouse Model of Alzheimer's Disease
Published in International journal of molecular sciences (21-12-2021)“…Alzheimer's disease (AD) is the leading cause of dementia among the elderly. Neuropathologically, AD is characterized by the deposition of a 39- to 42-amino…”
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Absolute Quantitative Targeted Monitoring of Potential Plasma Protein Biomarkers: A Pilot Study on Healthy Individuals
Published in Biomedicines (21-10-2024)“…The development of blood tests for the early detection of individual predisposition to socially significant diseases remains a pressing issue. In this pilot…”
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Integrating Proteomics and Lipidomics for Evaluating the Risk of Breast Cancer Progression: A Pilot Study
Published in Biomedicines (22-06-2023)“…Metastasis is a serious and often life-threatening condition, representing the leading cause of death among women with breast cancer (BC). Although the current…”
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Differential Diagnosis of Preeclampsia Based on Urine Peptidome Features Revealed by High Resolution Mass Spectrometry
Published in Diagnostics (Basel) (03-12-2020)“…Preeclampsia (PE) is a severe pregnancy complication, which may be considered as a systemic response in the second half of pregnancy to physiological failures…”
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miRNAs and Their Gene Targets-A Clue to Differentiate Pregnancies with Small for Gestational Age Newborns, Intrauterine Growth Restriction, and Preeclampsia
Published in Diagnostics (Basel) (20-04-2021)“…Despite the differences in the clinical manifestations of major obstetric syndromes, such as preeclampsia (PE) and intrauterine growth restriction (IUGR),…”
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Mass-Spectrometric Detection of SARS-CoV‑2 Virus in Scrapings of the Epithelium of the Nasopharynx of Infected Patients via Nucleocapsid N Protein
Published in Journal of proteome research (06-11-2020)“…The detection of viral RNA by polymerase chain reaction (PCR) is currently the main diagnostic tool for COVID-19 ( Eurosurveillance 2019, 25 (3), 1 ). The…”
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The Parallel Reaction Monitoring-Parallel Accumulation–Serial Fragmentation (prm-PASEF) Approach for Multiplexed Absolute Quantitation of Proteins in Human Plasma
Published in Analytical chemistry (Washington) (01-02-2022)“…Mass spectrometry (MS)-based quantitative proteomic methods have become some of the major tools for protein biomarker discovery and validation. The recently…”
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The Strategy for Peptidomic LC-MS/MS Data Analysis: The Case of Urinary Peptidome Study
Published in Methods in molecular biology (Clifton, N.J.) (2024)“…The study of urinary peptidome is an important area of research, which concerns the characterization of endogenous peptides, as well as the identification of…”
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Mass spectrometric studies of the variety of beta-amyloid proteoforms in Alzheimer's disease
Published in Mass spectrometry reviews (28-03-2022)“…This review covers the results of the application of mass spectrometric (MS) techniques to study the diversity of beta-amyloid (Aβ) peptides in human samples…”
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Interactive Estimation of Heterogeneity from Mass Spectrometry Imaging
Published in Analytical chemistry (Washington) (02-03-2021)“…In this work, we demonstrate a new approach for interactively assessing hyperspectral data spatial structures for heterogeneity using mass spectrometry…”
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Simultaneous express immunoassay of multiple cardiac biomarkers with an automatic platform in human plasma
Published in Talanta (Oxford) (01-03-2021)“…C-reactive protein, cystatin C, myoglobin, and D-dimer represent the inflammatory or thromboembolic status of the patient and play important roles in early…”
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Label‐free cervicovaginal fluid proteome profiling reflects the cervix neoplastic transformation
Published in Journal of mass spectrometry. (01-08-2019)“…Cervicovaginal fluid (CVF) is a valuable source of clinical information about the female reproductive tract in both nonpregnant and pregnant women. The aim of…”
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Effect of MSCs and MSC-Derived Extracellular Vesicles on Human Blood Coagulation
Published in Cells (Basel, Switzerland) (19-03-2019)“…Mesenchymal stem cells (MSCs) have emerged as a potent therapeutic tool for the treatment of a number of pathologies, including immune pathologies. However,…”
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