Search Results - "Bugreev, D. V"

Structure and mechanism of action of type IA DNA topoisomerases by Bugreev, D. V, Nevinsky, G. A

“…DNA topoisomerases are enzymes responsible for regulation of genomic DNA supercoiling. They participate in essential processes of cells such as replication,…”
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Possibilities of the method of step-by-step complication of ligand structure in studies of protein--nucleic acid interactions: mechanisms of functioning of some replication, repair, topoisomerization, and restriction enzymes by Bugreev, D V, Nevinsky, G A

“…X-Ray structure analysis is one of the most informative methods for investigation of enzymes. However, it does not provide quantitative estimation of the…”
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Interaction of human DNA topoisomerase I with specific sequence oligodeoxynucleotides by Bugreev, D.V., Vasyutina, E.L., Kolocheva, T.I., Buneva, V.N., Andoh, T., Nevinsky, G.A.

“…The interaction of human DNA topoisomerase I (topo I) with specific sequence oligodeoxynucleotides (ODNs) of different length and structure has been…”
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The structure and mechanism of the action of type-IB DNA topoisomerases by Bugreev, D. V., Nevinsky, G. A.

“…DNA topoisomerases responsible for the superspiralization of genomic DNA participate in almost all vitally important cell processes, including replication,…”
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The Mechanism of Specific Cleavage of Supercoiled DNA by Human DNA Topoisomerase I: The Effect of Ligand Structure on the Catalytic Step of Cleavage by Bugreev, D V, Buneva, V N, Nevinsky, G A

“…Eukaryotic DNA topoisomerase I (Topo) regulates the topological state of cell DNA and plays an important part in replication, transcription, repair, and…”
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Computer Analysis of Conformational and Physicochemical Properties of Nucleotide Sequences Cleavable by DNA Topoisomerase I by Oshchepkov, DYu, Bugreev, D V, Kolchanov, NA, Nevinsky, G A

“…DNA binding with enzymes is followed by specific adaptation of the DNA structure, including partial or almost complete melting, structural changes in the…”
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Interaction of single-stranded DNA with the second DNA-binding site of the RecA nucleoprotein filament by Bugreeva, I P, Bugreev, D V, Nevinsky, G A

“…RecA first forms a filament on single-stranded DNA (ssDNA), thereby forming the first site for ssDNA binding and, simultaneously, the second site for binding…”
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Dynamic, Thermodynamic, and Kinetic Basis for Recognition and Transformation of DNA by Human Immunodeficiency Virus Type 1 Integrase by Bugreev, Dmitrii V, Baranova, Svetlana, Zakharova, Olga D, Parissi, Vincent, Desjobert, Cécile, Sottofattori, Enzo, Balbi, Alessandro, Litvak, Simon, Tarrago-Litvak, Laura, Nevinsky, Georgy A

“…Specific interactions between retroviral integrase (IN) and long terminal repeats are required for insertion of viral DNA into the host genome. To characterize…”
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Interaction of the human topoisomerase I-DNA complex with oligo-1,3-thiazolecarboxamides and their oligonucleotide conjugates by Vasyutina, E L, Bugreev, D V, Ryabinin, V A, Sinyakov, A N, Buneva, V N, Nevinskii, G A

“…Nonnatural thiazole-containing oligopeptides (TCOs) bind to the DNA minor groove and inhibit the reaction catalyzed by human topoisomerase I (TopoI). The…”
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Physicochemical Basis of RecA Filamentation on Single-Stranded DNA by Bugreeva, I P, Bugreev, D V, Nevinsky, G A

“…Quantitative analysis was performed for the first time for the interaction of Escherichia coli RecA, which plays the central role in homologous recombination,…”
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High affinity interaction of mouse DNA topoisomerase I with di- and trinucleotides corresponding to specific sequences of supercoiled DNA cleaved chain by Bugreev, Dmitry V., Vasyutina, Elena L., Buneva, Valentina N., Yasui, Yoshihiro, Nishizawa, Miwako, Andoh, Toshiwo, Nevinsky, Georgy A.

“…Recently mouse DNA topoisomerase I (topo) was shown to possess high affinity for a single-stranded AAGACTTAG nonanucleotide ( K i=2.0 μM) corresponding to the…”
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The structure and mechanism of the action of type-IB DNA topoisomerases by Bugreev, D V, Nevinskiĭ, G A

“…DNA topoisomerases responsible for the superspiralization of genomic DNA participate in almost all vitally important cell processes, including replication,…”
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Ca2+ Activates Human Homologous Recombination Protein Rad51 by Modulating Its ATPase Activity by Bugreev, Dmitry V., Mazin, Alexander V.

“…Human Rad51 (hRad51) protein plays a key role in homologous recombination and DNA repair. hRad51 protein forms a helical filament on single-stranded DNA…”
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Ca super(2+) activates human homologous recombination protein Rad51 by modulating its ATPase activity by Bugreev, D V, Mazin, A V

“…Human Rad51 (hRad51) protein plays a key role in homologous recombination and DNA repair. hRad51 protein forms a helical filament on single-stranded DNA…”
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Interaction of single-stranded DNA with the second DNA-binding site of RecA nucleoprotein filament by Bugreeva, I P, Bugreev, D V, Nevinskiĭ, G A

“…RecA protein first forms filament on single-stranded (ss) DNA forming the first DNA-binding site for interaction with this ssDNA a formation of the second site…”
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Physico-chemical basis of RecA nucleo-protein filament formation on single by Bugreeva, I P, Bugreev, D V, Nevinskiĭ, G A

“…The analysis of RecA protein playing a central role in homologous recombination of E. coli with single-stranded DNAs of various structure and length on…”
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Activation of Human Meiosis-specific Recombinase Dmc1 by Ca2 by Bugreev, Dmitry V., Golub, Efim I., Stasiak, Alicja Z., Stasiak, Andrzej, Mazin, Alexander V.

“…Rad51 and its meiotic homolog Dmc1 are key proteins of homologous recombination in eukaryotes. These proteins form nucleoprotein complexes on single-stranded…”
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Computer analysis of conformational and physicochemical percularities of sequences cleaved by DNA topoisomerase I

“…After complexation of DNA with enzymes a specific adaptation of DNA structure including its partial or nearly complet melting, change of sugar-phosphate…”
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The mechanism of specific cleavage of supercoiled DNA by human DNA topoisomerase I: the effect of ligand structure on the catalytic step of reaction by Bugreev, D V, Buneva, V N, Nevinskiĭ, G A

“…Eukaryotic DNA topoisomerase I (Topo) regulates the topological state of cell DNA and plays an important part in replication, transcription, repair, and…”
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Inhibition of human DNA topoisomerase I by new DNA minor groove ligands: derivatives of oligo-1,3-thiazolecarboxamides by Bugreev, D V, Vasyutina, E L, Ryabinin, V A, Sinyakov, A N, Buneva, V N, Nevinsky, G A

“…A series of novel thiazole-containing oligopeptides (oligo-1,3-thiazolecarboxamides) interesting specifically with the minor groove of DNA was shown to inhibit…”
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