Search Results - "Bugner, Verena"
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Targeting Self-Renewal in High-Grade Brain Tumors Leads to Loss of Brain Tumor Stem Cells and Prolonged Survival
Published in Cell stem cell (07-08-2014)“…Cancer stem cells (CSCs) have been suggested as potential therapeutic targets for treating malignant tumors, but the in vivo supporting evidence is still…”
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Xenopus laevis insulin receptor substrate IRS‐1 is important for eye development
Published in Developmental dynamics (01-07-2011)“…Extracellular signal transduction into cells through ligand‐activated receptor tyrosine kinases, such as insulin‐like growth factor‐1 (IGF‐1) receptor (IGF‐1R)…”
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Peter Pan functions independently of its role in ribosome biogenesis during early eye and craniofacial cartilage development in Xenopus laevis
Published in Development (Cambridge) (01-06-2011)“…The Xenopus oocyte possesses a large maternal store of ribosomes, thereby uncoupling early development from the de novo ribosome biosynthesis required for cell…”
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FMR1/FXR1 and the miRNA pathway are required for eye and neural crest development
Published in Developmental biology (01-05-2010)“…FMR1 and FXR1 are RNA binding proteins interacting with the miRNA-induced silencing complex, RISC. Here we describe for the first time the function of these…”
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Pescadillo homologue 1 and Peter Pan function during Xenopus laevis pronephros development
Published in Biology of the cell (01-10-2011)“…Background information. pes1 (pescadillo homologue 1) and ppan (Peter Pan) are multifunctional proteins involved in ribosome biogenesis, cell proliferation,…”
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