Search Results - "Bugaj, Vladislav"

Activation of the epithelial Na+ channel in the collecting duct by vasopressin contributes to water reabsorption by Bugaj, Vladislav, Pochynyuk, Oleh, Stockand, James D

“…We used patch-clamp electrophysiology on isolated, split-open murine collecting ducts (CD) to test the hypothesis that regulation of epithelial sodium channel…”
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NOS1-dependent negative feedback regulation of the epithelial sodium channel in the collecting duct by Hyndman, Kelly A, Bugaj, Vladislav, Mironova, Elena, Stockand, James D, Pollock, Jennifer S

“…With an increase in urine flow there is a significant increase in shear stress against the renal epithelium including the inner medullary collecting duct,…”
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Collecting duct-specific endothelin B receptor knockout increases ENaC activity by Bugaj, Vladislav, Mironova, Elena, Kohan, Donald E, Stockand, James D

“…Collecting duct (CD)-derived endothelin-1 (ET-1) acting via endothelin B (ETB) receptors promotes Na(+) excretion. Compromise of ET-1 signaling or ETB…”
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Paracrine Regulation of the Epithelial Na+ Channel in the Mammalian Collecting Duct by Purinergic P2Y2 Receptor Tone by Pochynyuk, Oleh, Bugaj, Vladislav, Rieg, Timo, Insel, Paul A., Mironova, Elena, Vallon, Volker, Stockand, James D.

“…Growing evidence implicates a key role for extracellular nucleotides in cellular regulation, including of ion channels and renal function, but the mechanisms…”
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Aldosterone-independent regulation of the epithelial Na⁺ channel (ENaC) by vasopressin in adrenalectomized mice by Mironova, Elena, Bugaj, Vladislav, Roos, Karl P, Kohan, Donald E, Stockand, James D

“…The epithelial Na ⁺ channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN) is under negative-feedback regulation by the…”
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Dietary Na⁺ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y₂-receptor tone by Pochynyuk, Oleh, Rieg, Timo, Bugaj, Vladislav, Schroth, Jana, Fridman, Alla, Boss, Gerry R, Insel, Paul A, Stockand, James D, Vallon, Volker

“…Apical release of ATP and UTP can activate P2Y₂ receptors in the aldosterone-sensitive distal nephron (ASDN) and inhibit the open probability (Po) of the…”
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Regulation of the epithelial Na+ channel by endothelin-1 in rat collecting duct by Bugaj, Vladislav, Pochynyuk, Oleh, Mironova, Elena, Vandewalle, Alain, Medina, Jorge L, Stockand, James D

“…We used patch-clamp electrophysiology to investigate regulation of the epithelial Na+ channel (ENaC) by endothelin-1 (ET-1) in isolated, split-open rat…”
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Activation of ENaC by AVP contributes to the urinary concentrating mechanism and dilution of plasma by Mironova, Elena, Chen, Yu, Pao, Alan C, Roos, Karl P, Kohan, Donald E, Bugaj, Vladislav, Stockand, James D

“…Arginine vasopressin (AVP) activates the epithelial Na(+) channel (ENaC). The physiological significance of this activation is unknown. The present study…”
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Diminished Paracrine Regulation of the Epithelial Na+ Channel by Purinergic Signaling in Mice Lacking Connexin 30 by Mironova, Elena, Peti-Peterdi, Janos, Bugaj, Vladislav, Stockand, James D.

“…We tested whether ATP release through Connexin 30 (Cx30) is part of a local purinergic regulatory system intrinsic to the aldosterone-sensitive distal nephron…”
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Physiologic regulation of the epithelial sodium channel by phosphatidylinositides by Pochynyuk, Oleh, Bugaj, Vladislav, Stockand, James D

“…PURPOSE OF REVIEWEpithelial sodium channel (ENaC) activity is limiting for sodium reabsorption in the distal nephron. Humans regulate blood pressure by…”
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Purinergic Inhibition of ENaC Produces Aldosterone Escape by STOCKAND, James D, MIRONOVA, Elena, BUGAJ, Vladislav, RIEG, Timo, INSEL, Paul A, VALLON, Volker, PETI-PETERDI, Janos, POCHYNYUK, Oleh

“…The mechanisms underlying "aldosterone escape," which refers to the excretion of sodium (Na(+)) during high Na(+) intake despite inappropriately increased…”
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Molecular determinants of PI(4,5)P2 and PI(3,4,5)P3 regulation of the epithelial Na+ channel by Pochynyuk, Oleh, Tong, Qiusheng, Medina, Jorge, Vandewalle, Alain, Staruschenko, Alexander, Bugaj, Vladislav, Stockand, James D

“…Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) and phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P(3)) are physiologically important second…”
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Quantifying RhoA Facilitated Trafficking of the Epithelial Na+ Channel toward the Plasma Membrane with Total Internal Reflection Fluorescence-Fluorescence Recovery after Photobleaching by Pochynyuk, Oleh, Staruschenko, Alexander, Bugaj, Vladislav, LaGrange, Lila, Stockand, James D.

“…The epithelial Na+ channel (ENaC) plays a central role in control of epithelial surface hydration and vascular volume. Similar to other ion channels, ENaC…”
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Functional Properties of Endogenous Receptor- and Store-operated Calcium Influx Channels in HEK293 Cells by Bugaj, Vladislav, Alexeenko, Vadim, Zubov, Alexander, Glushankova, Lyuba, Nikolaev, Anton, Wang, Zhengnan, Kaznacheyeva, Elena, Bezprozvanny, Ilya, Mozhayeva, Galina N.

“…Activation of phospholipase C (PLC)-mediated signaling pathways in non-excitable cells causes the release of calcium (Ca2+) from inositol 1,4,5-trisphosphate…”
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Suppression of TRPC3 Leads to Disappearance of Store-operated Channels and Formation of a New Type of Store-independent Channels in A431 Cells by Kaznacheyeva, Elena, Glushankova, Lyuba, Bugaj, Vladislav, Zimina, Olga, Skopin, Anton, Alexeenko, Vadim, Tsiokas, Leonidas, Bezprozvanny, Ilya, Mozhayeva, Galina N.

“…In most non-excitable cells, calcium (Ca2+) release from the inositol 1,4,5-trisphosphate (InsP3)-sensitive intracellular Ca2+ stores is coupled to Ca2+ influx…”
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Giant multimodal heart motoneurons of Achatina fulica: a new cardioregulatory input in pulmonates by Zhuravlev, Vladimir, Bugaj, Vladislav, Kodirov, Sodikdjon, Safonova, Tatiana, Staruschenko, Alexandr

“…The regulation of the heartbeat by the two largest neurons, d-VLN and d-RPLN, on the dorsal surface of visceral and right parietal ganglia of Giant African…”
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Acute regulation of the epithelial Na+ channel by phosphatidylinositide 3-OH kinase signaling in native collecting duct principal cells by STARUSCHENKO, Alexander, POCHYNYUK, Oleh, VANDEWALLE, Alain, BUGAJ, Vladislav, STOCKAND, James D

“…Activity of the epithelial Na(+) channel (ENaC) is limiting for Na(+) reabsorption in the aldosterone-sensitive distal nephron. Hormones, including aldosterone…”
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Thiazolidinedione-Induced Fluid Retention Is Independent of Collecting Duct αENaC Activity by Vallon, Volker, Hummler, Edith, Rieg, Timo, Pochynyuk, Oleh, Bugaj, Vladislav, Schroth, Jana, Dechenes, Georges, Rossier, Bernard, Cunard, Robyn, Stockand, James

“…Thiazolidinediones are agonists of peroxisome proliferator–activated receptor γ (PPARγ) that can induce fluid retention and weight gain through unclear…”
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ENaC is active in the ASDN in the absence of mineralocorticoid by Mironova, Elena, Bugaj, Vladislav, Stockand, James

“…Abstract only Aldosterone controls extracellular volume and blood pressure by regulating Na + reabsorption via ENaC across epithelial cells of the…”
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Adenylyl Cyclase VI Mediates Vasopressin-Stimulated ENaC Activity by ROOS, Karl P, BUGAJ, Vladislav, MIRONOVA, Elena, STOCKAND, James D, RAMKUMAR, Nirupama, REES, Sara, KOHAN, Donald E

“…Vasopressin modulates sodium reabsorption in the collecting duct through adenylyl cyclase-stimulated cyclic AMP, which exists as multiple isoforms; the…”
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