Search Results - "Bugaj, L. J."

Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway by Bugaj, L J, Sabnis, A J, Mitchell, A, Garbarino, J E, Toettcher, J E, Bivona, T G, Lim, W A

“…The Ras-Erk (extracellular signal-regulated kinase) pathway encodes information in its dynamics; the duration and frequency of Erk activity can specify…”
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Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering by Bugaj, L. J., Spelke, D. P., Mesuda, C. K., Varedi, M., Kane, R. S., Schaffer, D. V.

“…Transmembrane receptors are the predominant conduit through which cells sense and transduce extracellular information into intracellular biochemical signals…”
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Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering by Bugaj, L. J., Spelke, D. P., Mesuda, C. K., Varedi, M., Kane, R. S., Schaffer, D. V.

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[177Lu-DOTAOTyr3]octreotate: comparison with [111In-DTPAo]octreotide in patients by Kwekkeboom, D J, Bakker, W H, Kooij, P P, Konijnenberg, M W, Srinivasan, A, Erion, J L, Schmidt, M A, Bugaj, J L, de Jong, M, Krenning, E P

“…The somatostatin analogue [DOTA0,Tyr3]octreotate has a nine-fold higher affinity for the somatostatin receptor subtype 2 as compared with [DOTA0,…”
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Arginase Modulates Myocardial Contractility by a Nitric Oxide Synthase 1-Dependent Mechanism by Steppan, Jochen, Ryoo, Sungwoo, Schuleri, Karl H., Gregg, Chris, Hasan, Rani K., White, A. Ron, Bugaj, Lukasz J., Khan, Mehnaz, Santhanam, Lakshmi, Nyhan, Daniel, Shoukas, Artin A., Hare, Joshua M., Berkowitz, Dan E.

“…Cardiac myocytes contain two constitutive NO synthase (NOS) isoforms with distinct spatial locations, which allows for isoformspecific regulation. One…”
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