Search Results - "Buga, Ana Maria"

ROS and Brain Diseases : The Good, the Bad, and the Ugly by Popa-Wagner, Aurel, Mitran, Smaranda, Sivanesan, Senthilkumar, Chang, Edwin, Buga, Ana-Maria

“…The brain is a major metabolizer of oxygen and yet has relatively feeble protective antioxidant mechanisms. This paper reviews the Janus-faced properties of…”
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Oxidative Stress-Induced Neurodegeneration and Antioxidative Strategies: Current Stage and Future Perspectives by Buga, Ana-Maria, Oancea, Carmen-Nicoleta

“…Neurodegenerative diseases (NDs) are the leading cause of neurological disorders, constituting a public health problem with an exponentially growing incidence…”
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Twenty-four hours hypothermia has temporary efficacy in reducing brain infarction and inflammation in aged rats by Sandu, Raluca Elena, Buga, Ana-Maria, Balseanu, Adrian Tudor, Moldovan, Mihai, Popa-Wagner, Aurel

“…Abstract Stroke is a major cause of disability for which no neuroprotective measures are available. Age is the principal nonmodifiable risk factor for this…”
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Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology by Sandu, Raluca, Buga, Ana, Uzoni, Adriana, Petcu, Eugen, Popa-Wagner, Aurel

“…Virtually all drug interventions that have been successful pre-clinically in experimental stroke have failed to prove their efficacy in a dinical setting. This…”
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Prolonged Gaseous Hypothermia Prevents the Upregulation of Phagocytosis-Specific Protein Annexin 1 and Causes Low-Amplitude EEG Activity in the Aged Rat Brain after Cerebral Ischemia by Joseph, Christy, Buga, Ana-Maria, Vintilescu, Raluca, Balseanu, Adrian Tudor, Moldovan, Mihai, Junker, Heike, Walker, Lary, Lotze, Martin, Popa-Wagner, Aurel

“…In aged humans, stroke is a major cause of disability for which no neuroprotective measures are available. In animal studies of focal ischemia, short-term…”
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Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke by Buga, Ana-Maria, Scholz, Claus Jürgen, Kumar, Senthil, Herndon, James G, Alexandru, Dragos, Cojocaru, Gabriel Radu, Dandekar, Thomas, Popa-Wagner, Aurel

“…Because most human stroke victims are elderly, studies of experimental stroke in the aged rather than the young rat model may be optimal for identifying…”
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Multimodal Approaches for Regenerative Stroke Therapies: Combination of Granulocyte Colony-Stimulating Factor with Bone Marrow Mesenchymal Stem Cells is Not Superior to G-CSF Alone by Balseanu, Adrian Tudor, Buga, Ana-Maria, Catalin, Bogdan, Wagner, Daniel-Christoph, Boltze, Johannes, Zagrean, Ana-Maria, Reymann, Klaus, Schaebitz, Wolf, Popa-Wagner, Aurel

“…Attractive therapeutic strategies to enhance post-stroke recovery of aged brains include methods of cellular therapy that can enhance the endogenous…”
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Long-term hypothermia reduces infarct volume in aged rats after focal ischemia by Florian, Baltromejus, Vintilescu, Raluca, Balseanu, Adrian Tudor, Buga, Ana-Maria, Grisk, Olaf, Walker, Lary C., Kessler, Christof, Popa-Wagner, Aurel

“…In aged humans, stroke is a major cause of disability for which no neuroprotective measures are available. A viable alternative to conventional drug-based…”
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Repeated PTZ treatment at 25-day intervals leads to a highly efficient accumulation of doublecortin in the dorsal hippocampus of rats by Buga, Ana-Maria, Vintilescu, Raluca, Balseanu, Adrian Tudor, Pop, Oltin Tiberiu, Streba, Costin, Toescu, Emil, Popa-Wagner, Aurel

“…Neurogenesis persists throughout life in the adult mammalian brain. Because neurogenesis can only be assessed in postmortem tissue, its functional significance…”
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Up-regulation of serotonin receptor 2B mRNA and protein in the peri-infarcted area of aged rats and stroke patients by Buga, Ana-Maria, Ciobanu, Ovidiu, Bădescu, George Mihai, Bogdan, Catalin, Weston, Ria, Slevin, Mark, Di Napoli, Mario, Popa-Wagner, Aurel

“…Despite the fact that a high proportion of elderly stroke patients develop mood disorders, the mechanisms underlying late-onset neuropsychiatric and…”
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The Role of Oxidative Stress and the Effects of Antioxidants on the Incidence of Infectious Complications of Chronic Lymphocytic Leukemia by Popa-Wagner, Aurel, Gaman, Mihnea-Alexandru, Buga, Ana-Maria, Gaman, Amelia Maria

“…Chronic lymphocytic leukemia (CLL) is characterized by a predominant humoral immune deficiency predisposing the patients to infections. Oxidative stress leads…”
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Vascular cognitive impairment, dementia, aging and energy demand. A vicious cycle by Popa-Wagner, A., Buga, Ana-Maria, Popescu, B., Muresanu, D.

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Poststroke Cell Therapy of the Aged Brain by Pourgolafshan, Pouya, Uzoni, Adriana, Filfan, Madalina, Popa-Wagner, Aurel, Buga, Ana-Maria

“…During aging, many neurodegenerative disorders are associated with reduced neurogenesis and a decline in the proliferation of stem/progenitor cells. The…”
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Granulocyte colony-stimulating factor and bone marrow mononuclear cells for stroke treatment in the aged brain by Buga, Ana-Maria, Scheibe, Johanna, Moller, Karoline, Ciobanu, Ovidiu, Posel, Claudia, Boltze, Johannes, Popa-Wagner, Aurel

“…Ischemic stroke swiftly induces a wide spectrum of pathophysiological sequelae, particularly in the aged brain. The translational failure of experimental…”
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Hormetic Neurobehavioral effects of low dose toxic chemical mixtures in real-life risk simulation (RLRS) in rats by Tsatsakis, Aristidis M., Docea, Anca Oana, Calina, Daniela, Buga, Ana Maria, Zlatian, Ovidiu, Gutnikov, Sergei, Kostoff, Ronald N., Aschner, Michael

“…The current study aims to assess the long-term effects of very low dose exposures to a complex chemical mixture on motor performance and behavioural changes in…”
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The Effect of Silver Nanoparticles on Antioxidant/Pro-Oxidant Balance in a Murine Model by Docea, Anca Oana, Calina, Daniela, Buga, Ana Maria, Zlatian, Ovidiu, Paoliello, M M B, Mogosanu, George Dan, Streba, Costin Teodor, Popescu, Elena Leocadia, Stoica, Alexandra Elena, Bîrcă, Alexandra Catalina, Vasile, Bogdan Ștefan, Grumezescu, Alexandru Mihai, Mogoanta, Laurentiu

“…This study aimed to evaluate the subacute effect of two types of Ag-NPs(EG-AgNPs and PVP-EG-AgNPs) on antioxidant/pro-oxidant balance in rats. Seventy Wistar…”
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Oxidative Stress and Inflammation Interdependence in Multiple Sclerosis by Padureanu, Rodica, Albu, Carmen Valeria, Mititelu, Radu Razvan, Bacanoiu, Manuela Violeta, Docea, Anca Oana, Calina, Daniela, Padureanu, Vlad, Olaru, Gabriela, Sandu, Raluca Elena, Malin, Ramona Denise, Buga, Ana-Maria

“…The study aims to explore the oxidative status related to inflammation in peripheral blood of stable relapsing-remitting multiple sclerosis (MS) patients with…”
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Pathophysiology of the vascular wall and its relevance for cerebrovascular disorders in aged rodents by Popa-Wagner, A, Pirici, D, Petcu, E B, Mogoanta, L, Buga, A-M, Rosen, C L, Leon, R, Huber, J

“…Chronic hypertension and cerebral amyloid angiopathy (CAA) are the main pathologies which can induce the rupture of cerebral vessels and intracerebral…”
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Perturbed cellular response to brain injury during aging by Popa-Wagner, Aurel, Buga, Ana-Maria, Kokaia, Zaal

“…Abstract Old age is associated with an enhanced susceptibility to stroke and poor recovery from brain injury, but the cellular processes underlying these…”
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Molecular and cellular stratagem of brain metastases associated with melanoma by Buga, Ana-Maria, Docea, Anca Oana, Albu, Carmen, Malin, Ramona Denise, Branisteanu, Daciana Elena, Ianosi, Gabriel, Ianosi, Simona Laura, Iordache, Andrei, Calina, Daniela

“…Tumors of the central nervous system are the most prevalent complications of melanoma, especially in the late stage of disease. Melanoma, lung and breast…”
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