Search Results - "Buettner, Matthew"

Improving Immunotherapy Through Glycodesign by Buettner, Matthew J, Shah, Sagar R, Saeui, Christopher T, Ariss, Ryan, Yarema, Kevin J

“…Immunotherapy is revolutionizing health care, with the majority of high impact "drugs" approved in the past decade falling into this category of therapy…”
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Exploiting metabolic glycoengineering to advance healthcare by Agatemor, Christian, Buettner, Matthew J., Ariss, Ryan, Muthiah, Keerthana, Saeui, Christopher T., Yarema, Kevin J.

“…Metabolic glycoengineering (MGE) is a technique for manipulating cellular metabolism to modulate glycosylation. MGE is used to increase the levels of natural…”
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Cell Line-, Protein-, and Sialoglycosite-Specific Control of Flux-Based Sialylation in Human Breast Cells: Implications for Cancer Progression by Saeui, Christopher T, Cho, Kyung-Cho, Dharmarha, Vrinda, Nairn, Alison V, Galizzi, Melina, Shah, Sagar R, Gowda, Prateek, Park, Marian, Austin, Melissa, Clarke, Amelia, Cai, Edward, Buettner, Matthew J, Ariss, Ryan, Moremen, Kelley W, Zhang, Hui, Yarema, Kevin J

“…Sialylation, a post-translational modification that impacts the structure, activity, and longevity of glycoproteins has been thought to be controlled primarily…”
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The Triticum Mosaic Virus Internal Ribosome Entry Site Relies on a Picornavirus-Like YX-AUG Motif To Designate the Preferred Translation Initiation Site and To Likely Target the 18S rRNA by Jaramillo-Mesa, Helena, Gannon, Megan, Holshbach, Elijah, Zhang, Jincan, Roberts, Robyn, Buettner, Matthew, Rakotondrafara, Aurélie M

“…Several viruses encode an internal ribosome entry site (IRES) at the 5' end of their RNA, which, unlike most cellular mRNAs, initiates translation in the…”
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Anticancer Properties of Hexosamine Analogs Designed to Attenuate Metabolic Flux through the Hexosamine Biosynthetic Pathway by Saeui, Christopher T., Shah, Sagar R., Fernandez-Gil, Beatriz I., Zhang, Cissy, Agatemor, Christian, Dammen-Brower, Kris, Mathew, Mohit P., Buettner, Matthew, Gowda, Prateek, Khare, Pratik, Otamendi-Lopez, Andrea, Yang, Shuang, Zhang, Hui, Le, Anne, Quinoñes-Hinojosa, Alfredo, Yarema, Kevin J.

“…Altered cellular metabolism is a hallmark of cancer pathogenesis and progression; for example, a near-universal feature of cancer is increased metabolic flux…”
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