Search Results - "Buen, Floyd"
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Elucidating Molecular Phenotypes Caused by the SORL1 Alzheimer’s Disease Genetic Risk Factor Using Human Induced Pluripotent Stem Cells
Published in Cell stem cell (02-04-2015)“…Predisposition to sporadic Alzheimer’s disease (SAD) involves interactions between a person’s unique combination of genetic variants and the environment. The…”
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The Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells
Published in Cell reports (Cambridge) (27-11-2013)“…Presenilin 1 (PS1) is the catalytic core of γ-secretase, which cleaves type 1 transmembrane proteins, including the amyloid precursor protein (APP). PS1 also…”
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ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-2010)“…Cholesterol metabolism has been implicated in the pathogenesis of several neurodegenerative diseases, including the abnormal accumulation of amyloid-β, one of…”
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Middle ear lipoma mimicking a congenital cholesteatoma: A case report and review of the literature
Published in International journal of pediatric otorhinolaryngology (01-12-2018)“…To describe a case of middle ear lipoma, review the current literature, and discuss the surgical approach. Published case reports in the English literature of…”
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Serious illness communication among patients with head and neck cancer
Published in Journal of clinical oncology (01-11-2019)“…Abstract only 2 Background: Head and neck cancer is associated with significant morbidity and mortality, yet little is known about the frequency and content of…”
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Concussive Brain Injury Enhances Fear Learning and Excitatory Processes in the Amygdala
Published in Biological psychiatry (1969) (15-02-2012)“…Background Mild traumatic brain injury (cerebral concussion) results in cognitive and emotional dysfunction. These injuries are a significant risk factor for…”
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Ankyloglossia: Last three-years of outpatient care at a tertiary referral center
Published in International journal of pediatric otorhinolaryngology (01-11-2019)“…Ankyloglossia is an oral anomaly characterized by a shortened, thickened lingual frenulum that may cause reduced tongue mobility. However, the diagnosis and…”
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Spindle Cell Lipoma Arising from the Supraglottis: A Case Report and Review of the Literature
Published in Head & neck pathology (Totowa, N.J.) (01-12-2021)“…Lipomas are common benign mesenchymal neoplasms. Although 13% of lipomas are found in the head and neck, only 0.6% have been reported in the larynx. Of all…”
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D-Cycloserine Restores Experience-Dependent Neuroplasticity after Traumatic Brain Injury in the Developing Rat Brain
Published in Journal of neurotrauma (15-04-2017)“…Traumatic brain injury (TBI) in children can cause persisting cognitive and behavioral dysfunction, and inevitably raises concerns about lost potential in…”
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ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in Alzheimer mice
Published in Alzheimer's & dementia (01-07-2010)Get full text
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P3‐285: ACAT1 gene ablation increases 24(S)‐hydroxycholesterol content in the brain and ameliorates amyloid pathology in Alzheimer mice
Published in Alzheimer's & dementia (01-07-2010)Get full text
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