Search Results - "Bueller, J A"

Functional GI disorders: from animal models to drug development by Mayer, E A, Bradesi, S, Chang, L, Spiegel, B M R, Bueller, J A, Naliboff, B D

“…Despite considerable efforts by academic researchers and by the pharmaceutical industry, the development of novel pharmacological treatments for irritable…”
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Sex differences in brain activity during aversive visceral stimulation and its expectation in patients with chronic abdominal pain: A network analysis by Labus, J.S., Naliboff, B.N., Fallon, J., Berman, S.M., Suyenobu, B., Bueller, J.A., Mandelkern, M., Mayer, E.A.

“…Differences in brain responses to aversive visceral stimuli may underlie previously reported sex differences in symptoms as well as perceptual and emotional…”
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Regional Mu Opioid Receptor Regulation of Sensory and Affective Dimensions of Pain by Zubieta, Jon-Kar, Smith, Yolanda R., Bueller, Joshua A., Xu, Yanjun, Kilbourn, Michael R., Jewett, Douglas M., Meyer, Charles R., Koeppe, Robert A., Stohler, Christian S.

“…The endogenous opioid system is involved in stress responses, in the regulation of the experience of pain, and in the action of analgesic opiate drugs. We…”
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ER stress induces epithelial differentiation in the mouse oesophagus by Rosekrans, Sanne L, Heijmans, Jarom, Büller, Nikè V J A, Westerlund, Jessica, Lee, Amy S, Muncan, Vanesa, van den Brink, Gijs R

“…Stress in the endoplasmic reticulum (ER) leads to activation of the unfolded protein response (UPR). Xbp1, a key component of the UPR has recently been linked…”
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Placebo effects mediated by endogenous opioid activity on mu-opioid receptors by Zubieta, Jon-Kar, Bueller, Joshua A, Jackson, Lisa R, Scott, David J, Xu, Yanjun, Koeppe, Robert A, Nichols, Thomas E, Stohler, Christian S

“…Reductions in pain ratings when administered a placebo with expected analgesic properties have been described and hypothesized to be mediated by the…”
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COMT$val^{158}met$Genotype Affects$\mu -Opioid$Neurotransmitter Responses to a Pain Stressor by Zubieta, Jon-Kar, Heitzeg, Mary M., Smith, Yolanda R., Bueller, Joshua A., Xu, Ke, Xu, Yanjun, Koeppe, Robert A., Stohler, Christian S., Goldman, David

“…Responses to pain and other Stressors are regulated by interactions between multiple brain areas and neurochemical systems. We examined the influence of a…”
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The HTR3A Polymorphism c. -42C>T Is Associated With Amygdala Responsiveness in Patients With Irritable Bowel Syndrome by Kilpatrick, Lisa A, Labus, Jennifer S, Coveleskie, Kristen, Hammer, Christian, Rappold, Gudrun, Tillisch, Kirsten, Bueller, Joshua A, Suyenobu, Brandall, Jarcho, Johana M, McRoberts, Jim A, Niesler, Beate, Mayer, Emeran A

“…Background & Aims 5-Hydroxytryptamine (5-HT)3 receptor (5-HT3 R) antagonists are effective in treating patients with irritable bowel syndrome (IBS) and have…”
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Altered Central μ-Opioid Receptor Binding After Psychological Trauma by Liberzon, Israel, Taylor, Stephan F, Phan, K. Luan, Britton, Jennifer C, Fig, Lorraine M, Bueller, Joshua A, Koeppe, Robert A, Zubieta, Jon-Kar

“…Background Functional neuroimaging studies have detected abnormal limbic and paralimbic activation to emotional probes in posttraumatic stress disorder (PTSD),…”
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mu-opioid receptor-mediated antinociceptive responses differ in men and women by Zubieta, Jon-Kar, Smith, Yolanda R, Bueller, Joshua A, Xu, Yanjun, Kilbourn, Michael R, Jewett, Douglas M, Meyer, Charles R, Koeppe, Robert A, Stohler, Christian S

“…Sex differences in the experience of clinical and experimental pain have been reported. However, the neurobiological sources underlying the variability in pain…”
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Impact of Mindfulness Meditation Training on the Default Network by Kilpatrick, LA, Suyenobu, BY, Smith, SR, Bueller, JA, Mayer, EA, Naliboff, BD

“…Most notably, MBSR-trained subjects, compared to wait list controls, showed significantly increased DMN connectivity with the left dorsal and inferior lateral…”
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Rage signalling promotes intestinal tumourigenesis by Heijmans, J, Büller, N V J A, Hoff, E, Dihal, A A, van der Poll, T, van Zoelen, M A D, Bierhaus, A, Biemond, I, Hardwick, J C H, Hommes, D W, Muncan, V, van den Brink, G R

“…Development of colon cancer is a multistep process that is regulated by intrinsic and extrinsic cellular signals. Extrinsic factors include molecular patterns…”
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Increased coupling within an emotional arousal circuit following threat conditioning in patients with Irritable Bowel Syndrome (IBS) by Bueller, JA, Labus, JS, Suyenobu, BY, Stains, J, Tillisch, K, Vianna, EP, Jarcho, J, Naliboff, BD, Mayer, EA

“…Introduction IBS is characterized by recurrent gastrointestinal pain/discomfort and is associated with significant decrements in health-related quality of…”
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Placebo Effects Mediated by Endogenous Opioid Activity on {micro}-Opioid Receptors by Zubieta, Jon-Kar, Bueller, Joshua A, Jackson, Lisa R, Scott, David J, Xu, Yanjun, Koeppe, Robert A, Nichols, Thomas E, Stohler, Christian S

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COMT val super(158)met Genotype Affects mu -Opioid Neurotransmitter Responses to a Pain Stressor by Zubieta, J-K, Heitzeg, M M, Smith, Y R, Bueller, JA, Xu, K, Xu, Y, Koeppe, R A, Stohler, C S, Goldman, D

“…Responses to pain and other stressors are regulated by interactions between multiple brain areas and neurochemical systems. We examined the influence of a…”
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COMT val158met genotype affects μ-opioid neurotransmitter responses to a pain stressor by ZUBIETA, Jon-Kar, HEITZEG, Mary M, SMITH, Yolanda R, BUELLER, Joshua A, KE XU, YANJUN XU, KOEPPE, Robert A, STOHLER, Christian S, GOLDMAN, David

“…Responses to pain and other stressors are regulated by interactions between multiple brain areas and neurochemical systems. We examined the influence of a…”
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Regulation of Human Affective Responses by Anterior Cingulate and Limbic µ-Opioid Neurotransmission by Zubieta, Jon-Kar, Ketter, Terence A, Bueller, Joshua A, Xu, Yanjun, Kilbourn, Michael R, Young, Elizabeth A, Koeppe, Robert A

“…BACKGROUND Human affective responses appear to be regulated by limbic and paralimbic circuits. However, much less is known about the neurochemical systems…”
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