Search Results - "Buechter, D D"

Calcium phosphate/thermoresponsive hyaluronan hydrogel composite delivering hydrophilic and hydrophobic drugs by Petta, Dalila, Fussell, Garland, Hughes, Lisa, Buechter, Douglas D., Sprecher, Christoph M., Alini, Mauro, Eglin, David, D'Este, Matteo

“…Advanced synthetic biomaterials that are able to reduce or replace the need for autologous bone transplantation are still a major clinical need in…”
Get full text

Co-translational incorporation of trans-4-hydroxyproline into recombinant proteins in bacteria by Buechter, Douglas D, Paolella, David N, Leslie, Bridget S, Brown, Melissa S, Mehos, Karen A, Gruskin, Elliott A

“…Trans-4-hydroxyproline (Hyp) in eukaryotic proteins arises from post-translational modification of proline residues. Because the modification enzyme is not…”
Get full text

In Vitro and In Vivo Antibacterial Activities of Heteroaryl Isothiazolones against Resistant Gram-Positive Pathogens by PUCCI, Michael J, JIJUN CHENG, PODOS, Steven D, THOMA, Christy L, THANASSI, Jane A, BUECHTER, Douglas D, MUSHTAQ, Gohar, VIGLIOTTI, Gerald A, BRADBURY, Barton J, DESHPANDE, Milind

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Oxidation of γ-irradiated microbial cellulose results in bioresorbable, highly conformable biomaterial by Czaja, Wojciech, Kyryliouk, Dmytro, DePaula, C. Alex, Buechter, Douglas D.

“…ABSTRACT Conformability to tissues and adequate mechanical strength are clinically useful properties of resorbable biomaterials used in soft tissue repair…”
Get full text

Lactoferricin mediates anti-inflammatory and anti-catabolic effects via inhibition of IL-1 and LPS activity in the intervertebral disc by Kim, Jae-Sung, Ellman, Michael B., Yan, Dongyao, An, Howard S., KC, Ranjan, Li, Xin, Chen, Di, Xiao, Guozhi, Cs-Szabo, Gabriella, Hoskin, David W., Buechter, Doug D., Van Wijnen, Andre J., Im, Hee-Jeong

“…The catabolic cytokine interleukin‐1 (IL‐1) and endotoxin lipopolysaccharide (LPS) are well‐known inflammatory mediators involved in degenerative disc disease,…”
Get full text

Mandelate pathway of Pseudomonas putida: sequence relationships involving mandelate racemase, (S)-mandelate dehydrogenase, and benzoylformate decarboxylase and expression of benzoylformate decarboxylase in Escherichia coli by Tsou, Amy Y, Ransom, Stephen C, Gerlt, John A, Buechter, Douglas D, Babbitt, Patricia C, Kenyon, George L

“…The genes that encode the five known enzymes of the mandelate pathway of Pseudomonas putida (ATCC 12633), mandelate racemase (mdlA), (S)-mandelate…”
Get full text

The active site of creatine kinase. Affinity labeling of cysteine 282 with N-(2,3-epoxypropyl)-N-amidinoglycine by Buechter, D D, Medzihradszky, K F, Burlingame, A L, Kenyon, G L

“…Epoxycreatine (N-(2,3-epoxypropyl)-N-amidinoglycine) is an affinity label of creatine kinase that irreversibly and completely inactivates the enzyme (Marletta,…”
Get full text

Dissection of a class II tRNA synthetase: Determinants for minihelix recognition are tightly associated with domain for amino acid activation by Buechter, Douglas D, Schimmel, Paul

“…The ten class II aminoacyl-tRNA synthetases are large homo- and hetero-oligomeric proteins that share three conserved sequence motifs. Within this class,…”
Get full text

Functional Dissection of a Predicted Class-Defining Motif in a Class II tRNA Synthetase of Unknown Structure by Davis, Matthew W, Buechter, Douglas D, Schimmel, Paul

“…A core of eight beta-strands and three alpha-helices was recently predicted for the active site domain of Escherichia coli alanyl-tRNA synthetase, an enzyme of…”
Get full text

Minor groove recognition of the critical acceptor helix base pair by an appended module of a class II tRNA synthetase by Buechter, Douglas D, Schimmel, Paul

“…The class-defining active site domain of the 10 class II tRNA synthetases is well conserved and, based on the crystal structure of aspartyl-tRNA synthetase,…”
Get full text

Removal of a Proteolytic Activity Associated with Aggregates Formed from Expression of Creatine Kinase in Escherichia coli Leads to Improved Recovery of Active Enzyme by Babbitt, Patricia C, West, Brian L, Buechter, Douglas D, Kuntz, Irwin D, Kenyon, George L

“…Expression of creatine kinase (CK) from a Torpedo californica electric organ cDNA in Escherichia coli results in an insoluble protein product with no…”
Get full text

Aminoacylation of RNA minihelices: implications for tRNA synthetase structural design and evolution by Buechter, D D, Schimmel, P

“…The genetic code is based on the aminoacylation of tRNA with amino acids catalyzed by the aminoacyl-tRNA synthetases. The synthetases are constructed from…”
Get more information

Free radicals and oxygen toxicity by BUECHTER, D. D

“…Most organisms are constantly exposed to molecular oxygen, and this has become a requirement of life for many of them. Oxygen is not totally innocuous,…”
Get full text

Isothiazoloquinolones with Enhanced Antistaphylococcal Activities against Multidrug-Resistant Strains:  Effects of Structural Modifications at the 6-, 7-, and 8-Positions by Wang, Qiuping, Lucien, Edlaine, Hashimoto, Akihiro, Pais, Godwin C. G., Nelson, David M., Song, Yongsheng, Thanassi, Jane A., Marlor, Christopher W., Thoma, Christy L., Cheng, Jijun, Podos, Steven D., Ou, Yangsi, Deshpande, Milind, Pucci, Michael J., Buechter, Douglas D., Bradbury, Barton J., Wiles, Jason A.

“…We describe the biological evaluation of isothiazoloquinolones (ITQs) having structural modifications at the 6-, 7-, and 8-positions. Addition of a methoxy…”
Get full text

Idiographic representation of conserved domain of a class II tRNA synthetase of unknown structure by Pouplana, Lluis Ribasde, Buechter, Douglas D., Davis, Matthew W., Schimmel, Paul

Get full text

Minor Groove Recognition of the Critical Acceptor Helix Base Pair by an Appended Module of a Class II tRNA Synthetase. [Erratum to document cited in CA122:285491] by Buechter, Douglas D, Schimmel, Paul

Get full text

Co-translational Incorporation ofTrans-4-Hydroxyproline into Recombinant Proteins in Bacteria by Buechter, Douglas D., Paolella, David N., Leslie, Bridget S., Brown, Melissa S., Mehos, Karen A., Gruskin, Elliott A.

“…Trans-4-hydroxyproline (Hyp) in eukaryotic proteins arises from post-translational modification of proline residues. Because the modification enzyme is not…”
Get full text

Studies on the Pyrrolizidine Antitumor Agent, Clazamycin: Interconversion of Clazamycins A and B by Buechter, Douglas D, Thurston, David E

“…Clazamycin, a novel pyrrolizidine antitumor antibiotic, exists in aqueous solution as a mixture of two epimers, clazamycins A and B [1A, 1B], the ratio of…”
Get full text

Studies on the stability of vinblastine sulfate in aqueous solution by Black, J, Buechter, D D, Chinn, J W, Gard, J, Thurston, D E

“…A stability study on vinblastine sulfate (1) in aqueous solution at several different temperatures (in the absence of light) has been undertaken…”
Get more information

The principal islet of the Coho salmon (Oncorhyncus kisutch) contains the BB isoenzyme of creatine kinase by White, K C, Babbitt, P C, Buechter, D D, Kenyon, G L

“…The importance of creatine kinase (E.C. 2.7.3.2) in endocrine tissues has been generally overlooked. Using a specific radiometric assay, we have demonstrated…”
Get more information