Search Results - "Budzyn, K"

Mechanisms of augmented vasoconstriction induced by 5‐hydroxytryptamine in aortic rings from spontaneously hypertensive rats by Budzyn, K, Ravi, R M, Miller, A A, Sobey, C G

“…Background and purpose: To test whether development of enhanced vasoconstriction to 5‐hydroxytryptamine (5‐HT; serotonin) in SHR was temporally related to…”
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Targeting Rho and Rho-kinase in the treatment of cardiovascular disease by Budzyn, Klaudia, Marley, Philip D., Sobey, Christopher G.

“…The small GTPase Rho and its downstream effector Rho-kinase contribute to agonist-induced vascular contraction via Ca 2+ sensitization. Reasonably selective…”
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A microscopic view of false tendons in the left ventricle of the human heart by Lotkowski, D, Grzybiak, M, Kozłowski, D, Budzyn, K, Kuta, W

“…Research was conducted on material consisting of 45 fetal, newborn, infant and adult human hearts. False tendons in fetal, newborn and infant hearts were made…”
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Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo by CHRISSOBOLIS, Sophocles, BUDZYN, Klaudia, MARLEY, Philip D, SOBEY, Christopher G

“…Premenopausal women are less susceptible to cardiovascular diseases than men or postmenopausal women. Such disease states are often associated with increased…”
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Segmental differences in the roles of rho-kinase and protein kinase C in mediating vasoconstriction by Budzyn, Klaudia, Paull, Michelle, Marley, Philip D, Sobey, Christopher G

“…Rho-kinase and protein kinase C (PKC) have each been reported to mediate vasoconstriction via calcium sensitization. However, the relative contributions of…”
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Opposing roles of endothelial and smooth muscle phosphatidylinositol 3-kinase in vasoconstriction: effects of rho-kinase and hypertension by Budzyn, Klaudia, Marley, Philip D, Sobey, Christopher G

“…Phosphatidylinositol 3-kinase (PI3K) can activate endothelial nitric oxide synthase (eNOS), leading to production of the vasodilator NO. In contrast, vascular…”
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Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice by Budzyn, Klaudia, Marley, Philip D, Sobey, Christopher G

“…We tested the hypothesis that endothelial nitric oxide (NO) synthase (eNOS)-derived NO modulates rho-kinase-mediated vascular contraction. Because…”
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Abstract: 562 DIFFERENTIAL EFFECTS OF ANGIOTENSIN II ON INFLAMMATION IN THE PERIVASCULAR AND VISCERAL ADIPOSE TISSUE by Guzik, T, Mihulka, K, Budzyn, K, Korbut, R

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Vascular rho kinases and their potential therapeutic applications by Budzyn, Klaudia, Sobey, Christopher G

“…Over the last decade, numerous advances have been made in characterizing the various roles of rho kinase in vascular function. In light of extensive evidence…”
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