Search Results - "Budnick, James A."

Quantitative Variation in m.3243A > G Mutation Produce Discrete Changes in Energy Metabolism by McMillan, Ryan P., Stewart, Sidney, Budnick, James A., Caswell, Clayton C., Hulver, Matthew W., Mukherjee, Konark, Srivastava, Sarika

“…Mitochondrial DNA (mtDNA) 3243A > G tRNALeu (UUR) heteroplasmic mutation (m.3243A > G) exhibits clinically heterogeneous phenotypes. While the high mtDNA…”
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Characterizing the transport and utilization of the neurotransmitter GABA in the bacterial pathogen Brucella abortus by Budnick, James A, Sheehan, Lauren M, Benton, Angela H, Pitzer, Joshua E, Kang, Lin, Michalak, Pawel, Roop, R. Martin, Caswell, Clayton C

“…The neurotransmitter gamma-aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the human brain; however, it is becoming more evident…”
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Complete Genome Sequence of Klebsiella pneumoniae Strain ATCC 43816 by Budnick, James A, Bina, X Renee, Bina, James E

“…is a member of that causes a multitude of infections in compromised and healthy individuals. The rise of hypervirulent and multiple-drug-resistant strains has…”
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Enemy of My Enemy: A Novel Insect-Specific Flavivirus Offers a Promising Platform for a Zika Virus Vaccine by Porier, Danielle L, Wilson, Sarah N, Auguste, Dawn I, Leber, Andrew, Coutermarsh-Ott, Sheryl, Allen, Irving C, Caswell, Clayton C, Budnick, James A, Bassaganya-Riera, Josep, Hontecillas, Raquel, Weger-Lucarelli, James, Weaver, Scott C, Auguste, Albert J

“…Vaccination remains critical for viral disease outbreak prevention and control, but conventional vaccine development typically involves trade-offs between…”
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Finding Order in the Chaos: Outstanding Questions in Klebsiella pneumoniae Pathogenesis by Gonzalez-Ferrer, Shekina, Peñaloza, Hernán F, Budnick, James A, Bain, William G, Nordstrom, Hayley R, Lee, Janet S, Van Tyne, Daria

“…are Gram-negative facultative anaerobes that are found within host-associated commensal microbiomes, but they can also cause a wide range of infections that…”
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Defining the regulatory mechanism of NikR, a nickel-responsive transcriptional regulator, in Brucella abortus by Budnick, James A, Prado-Sanchez, Evymarie, Caswell, Clayton C

“…Metals are essential micronutrients for virtually all forms of life, but metal acquisition is a double-edged sword, because high concentrations of divalent…”
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Vibrio cholerae TolC Is Required for Expression of the ToxR Regulon by Weng, Yuding, Fields, Edith G, Bina, Thomas F, Budnick, James A, Kunkle, Dillon E, Bina, X Renee, Bina, James E

“…Vibrio cholerae is a Gram-negative bacterium that causes the enteric disease cholera. V. cholerae colonization of the human intestine is dependent on the…”
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Characterization of Three Small Proteins in Brucella abortus Linked to Fucose Utilization by Budnick, James A, Sheehan, Lauren M, Kang, Lin, Michalak, Pawel, Caswell, Clayton C

“…Elucidating the function of proteins <50 amino acids in length is no small task. Nevertheless, small proteins can play vital roles in the lifestyle of bacteria…”
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The Endoribonuclease RNase E Coordinates Expression of mRNAs and Small Regulatory RNAs and Is Critical for the Virulence of Brucella abortus by Sheehan, Lauren M, Budnick, James A, Fyffe-Blair, Jaquille, King, Kellie A, Settlage, Robert E, Caswell, Clayton C

“…RNases are key regulatory components in prokaryotes, responsible for the degradation and maturation of specific RNA molecules at precise times. Specifically,…”
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A LysR‐family transcriptional regulator required for virulence in Brucella abortus is highly conserved among the α‐proteobacteria by Sheehan, Lauren M., Budnick, James A., Blanchard, Catlyn, Dunman, Paul M., Caswell, Clayton C.

“…Summary Small RNAs are principal elements of bacterial gene regulation and physiology. Two small RNAs in Brucella abortus, AbcR1 and AbcR2, are required for…”
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Sinorhizobium meliloti YbeY is a zinc-dependent single-strand specific endoribonuclease that plays an important role in 16S ribosomal RNA processing by Babu, Vignesh M P, Sankari, Siva, Budnick, James A, Caswell, Clayton C, Walker, Graham C

“…Single-strand specific endoribonuclease YbeY has been shown to play an important role in the processing of the 3' end of the 16S rRNA in Escherichia coli. Lack…”
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Coordinated Zinc Homeostasis Is Essential for the Wild-Type Virulence of Brucella abortus by Sheehan, Lauren M, Budnick, James A, Roop, R. Martin, Caswell, Clayton C

“…Metal homeostasis in bacterial cells is a highly regulated process requiring intricately coordinated import and export, as well as precise sensing of…”
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A central role for the transcriptional regulator VtlR in small RNA-mediated gene regulation in Agrobacterium tumefaciens by Budnick, James A., Sheehan, Lauren M., Ginder, Miranda. J., Failor, Kevin C., Perkowski, Julia. M., Pinto, John. F., Kohl, Kirsten A., Kang, Lin, Michalak, Pawel, Luo, Li, Heindl, Jason E., Caswell, Clayton C.

“…LysR-type transcriptional regulators (LTTRs) are the most common type of transcriptional regulators in prokaryotes and function by altering gene expression in…”
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Proline utilization system is required for infection by the pathogenic α-proteobacterium Brucella abortus by Caudill, Mitchell T, Budnick, James A, Sheehan, Lauren M, Lehman, Christian R, Purwantini, Endang, Mukhopadhyay, Biswarup, Caswell, Clayton C

“…Proline utilization (Put) systems have been described in a number of bacteria; however, the importance and functionality of the Put system in the intracellular…”
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Endoribonuclease YbeY Is Linked to Proper Cellular Morphology and Virulence in Brucella abortus by Budnick, James A, Sheehan, Lauren M, Colquhoun, Jennifer M, Dunman, Paul M, Walker, Graham C, Roop, 2nd, R Martin, Caswell, Clayton C

“…The YbeY endoribonuclease is one of the best-conserved proteins across the kingdoms of life. In the present study, we demonstrated that YbeY in is linked to a…”
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Complete Genome Sequence of Klebsiella pneumoniae Strain ATCC 43816 by Budnick, James A., Bina, X. Renee, Bina, James E.

“…Klebsiella pneumoniae is a member of Enterobacteriaceae that causes a multitude of infections in compromised and healthy individuals. The rise of hypervirulent…”
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A LysR ‐family transcriptional regulator required for virulence in B rucella abortus is highly conserved among the α‐proteobacteria by Sheehan, Lauren M., Budnick, James A., Blanchard, Catlyn, Dunman, Paul M., Caswell, Clayton C.

“…Small RNAs are principal elements of bacterial gene regulation and physiology. Two small RNAs in B rucella abortus , Abc R 1 and Abc R 2, are required for…”
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A LysR-family transcriptional regulator required for virulence in Brucella abortus is highly conserved among the a-proteobacteria by Sheehan, Lauren M, Budnick, James A, Blanchard, Catlyn, Dunman, Paul M, Caswell, Clayton C

“…Small RNAs are principal elements of bacterial gene regulation and physiology. Two small RNAs in Brucella abortus, AbcR1 and AbcR2, are required for wild-type…”
Get full text